Assessing the risk of antimicrobial resistance and potential environmental harm through national-scale surveillance of antimicrobials in hospital and community wastewater

• Published in: Environment international Vol. 202; p. 109606
• Main Authors: Byrnes, Neil Andrew, Silvester, Reshma, Cross, Gareth, Weightman, Andrew J., Jones, Davey L., Kasprzyk-Hordern, Barbara
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.08.2025; Elsevier
• Subjects: Anti-Infective Agents - analysis; Antibiotic; Antimicrobial resistance; Environmental Monitoring; Environmental risk assessment; Hospitals; One Health; Public health; Risk Assessment; Wales; Waste Disposal, Fluid; Wastewater - analysis; Wastewater - chemistry; Water Pollutants, Chemical - analysis; Wales; Environmental risk assessment; Antibiotic; Antimicrobial resistance; Public health; One Health

[Display omitted] •Ciprofloxacin and clarithromycin concentrations frequently above PNECs.•High concentrations of sulfamethoxazole and trimethoprim found in hospital effluent.•Hospital effluent wastewater is a hot spot for induction of antimicrobial resistance.•Direct disposal of antimicrobials was...