Emerging roles for hypothalamic microglia as regulators of physiological homeostasis

• Published in: Frontiers in neuroendocrinology Vol. 54; p. 100748
• Main Authors: Rosin, Jessica M., Kurrasch, Deborah M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2019
• Subjects: Animals; Anorexia; Homeostasis; Homeostasis - physiology; Humans; Hypothalamus; Hypothalamus - growth & development; Hypothalamus - immunology; Hypothalamus - metabolism; Hypothalamus - physiology; Inflammation; Inflammation - immunology; Inflammation - metabolism; Microglia; Microglia - immunology; Microglia - metabolism; Microglia - physiology; Neuroendocrine; Obesity; Obesity - immunology; Obesity - metabolism; Sex Characteristics; Sexual dimorphism; Stress; Stress, Psychological - immunology; Stress, Psychological - metabolism; Obesity; Anorexia; Neuroendocrine; Homeostasis; Inflammation; Hypothalamus; Sexual dimorphism; Stress; Microglia

•Microglia play important roles in both the development and continued function of the hypothalamus throughout life.•Microglia could be key regulators of homeostasis by sensing cues external to the CNS and acting through the hypothalamus.•Microglial dysfunction can result in neuroendocrine diseases w...