Broadening the Scope of Biocatalysis Engineering by Tailoring Enzyme Microenvironment: A Review

• Published in: Catalysis letters Vol. 153; no. 5; pp. 1227 - 1239
• Main Authors: Li, Wenqian, Bilal, Muhammad, Singh, Anil Kumar, Sher, Farooq, Ashraf, S. Salman, Franco, Marcelo, Américo-Pinheiro, Juliana Heloisa Pinê, Iqbal, Hafiz M. N.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.05.2023; Springer; Springer Nature B.V
• Subjects: biocatalysis; biocatalysts; Catalysis; Catalysts; Chemical reaction, Rate of; Chemistry; Chemistry and Materials Science; dissociation; Engineering; Enzymes; immobilized enzymes; Industrial Chemistry/Chemical Engineering; Organometallic Chemistry; Physical Chemistry; Proteins; Reaction kinetics; State-of-the-art reviews; substrate specificity; Substrates; Vapor phases; Protein engineering; Yield enhancement strategies; Bio-catalysis; Microenvironment engineering; Computational modeling; Enzyme engineering

The rational design of catalysts that fine-tune/mimics the enzyme microenvironment remains the subject of supreme interest. Several strategies moving from traditional to technologically advanced methods have been proposed and deployed to develop high efficacy enzymes. There is a plethora of literatu...