Antibody durability is influenced by interleukin-2 production by undifferentiated memory T helper cells and extensive B cell clonal expansion - Isogawa, Masanori; Shinoda, Masahiro; Kotaki, Ryutaro; Terahara, Kazutaka; Onodera, Taishi; Kabasawa, Kiyomi; Toyama-Kousaka, Mio; Fujisawa, Mizuki; Watanabe, Mitsukaze; Tonouchi, Keisuke; Terooatea, Tommy; Kitano, Ayumi; et al. (Cell reports (Cambridge), 2025)
Keywords: Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; antibody durability; B-Lymphocytes - immunology; BACH2; CD4-Positive T-Lymphocytes - immunology; Cell Differentiation; COVID-19 - immunology; COVID-19 - prevention & control; CP: Immunology; helper T cells; Humans; Immunologic Memory; interleukin-2; Interleukin-2 - biosynthesis; Interleukin-2 - immunology; Interleukin-2 - metabolism; Interleukin-21; Memory T Cells - immunology; mRNA vaccine; SARS-CoV-2 - immunology; Spike Glycoprotein, Coronavirus - immunology; T-Lymphocytes, Helper-Inducer - immunology; CP: Immunology; interleukin-2; antibody durability; helper T cells; BACH2; mRNA vaccine