Distinguishing Laterality in Brain Injury in Rabbit Fetal Magnetic Resonance Imaging Using Novel Volume Rendering Techniques

• Published in: Developmental neuroscience Vol. 47; no. 1; p. 55
• Main Authors: Ambwani, Gaurav, Shi, Zhongjie, Luo, Kehuan, Jeong, Jeong-Won, Tan, Sidhartha
• Format: Journal Article
• Language: English
• Published: Switzerland 01.02.2025
• Subjects: Animals; Brain - diagnostic imaging; Brain - pathology; Brain Injuries - diagnostic imaging; Diffusion Magnetic Resonance Imaging - methods; Female; Fetus - diagnostic imaging; Functional Laterality - physiology; Hypoxia-Ischemia, Brain - diagnostic imaging; Magnetic Resonance Imaging - methods; Pregnancy; Rabbits; Developing brain; Animal models; Reperfusion-reoxygenation; Perinatal brain injury; Hypoxic-ischemic encephalopathy

Our laboratory has been exploring the MRI detection of fetal brain injury, which previously provided a prognostic biomarker for newborn hypertonia in an animal model of cerebral palsy (CP). The biomarker relies on distinct patterns of diffusion-weighted imaging-defined apparent diffusion coefficient...