Decreased Serum Paraoxonase-1 Activity during Intestinal Nematode (Nippostrongylus brasiliensis) Infection in Rats

• Published in: The American journal of tropical medicine and hygiene Vol. 78; no. 5; pp. 770 - 776
• Main Authors: Farid, Ayman Samir, Nakahara, Keiko, Murakami, Noboru, Hayashi, Toshiharu, Horii, Yoichiro
• Format: Journal Article
• Language: English
• Published: Lawrence, KS ASTMH 01.05.2008; Allen Press
• Subjects: Animals; Aryldialkylphosphatase - blood; Biological and medical sciences; Carboxylic Ester Hydrolases - blood; Cytokines - blood; Feces - parasitology; Female; Infectious diseases; Inflammation - blood; Inflammation - parasitology; Larva; Male; Medical sciences; Nippostrongylus - growth & development; Oviposition; Rats; Rats, Wistar; Strongylida Infections - blood; Rat; Enzyme; Rodentia; Esterases; Parasitosis; Helminthiasis; Nippostrongylus brasiliensis; Infection; Phosphoric triester hydrolases; Vertebrata; Experimental disease; Mammalia; Animal; Nematode disease; Helmintha; Hydrolases; Tropical medicine; Serum; Nemathelminthia; Aryldialkylphosphatase; Invertebrata; Nematoda

Reduced paraoxonase-1 (PON1) activity has been observed in a number of pathological conditions; however, little is known about the effects of intestinal nematode infections, such as Nippostrongylus brasiliensis , on paraoxonase activity. We observed a significant reduction in serum paraoxonase and a...