Gemin 6 and 7 Lend a Hand to snRNP Assembly

• Published in: Structure (London) Vol. 13; no. 6; pp. 833 - 834
• Main Authors: Leung, Adelaine K.W., Nagai, Kiyoshi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2005
• Subjects: Carrier Proteins - chemistry; Dimerization; Humans; Models, Chemical; Motor Neurons - chemistry; Nuclear Proteins - chemistry; Ribonucleoproteins, Small Nuclear; Ribonucleoproteins, Small Nucleolar - metabolism

A structure of the Gemin 6 and 7 heterodimer ( Ma et al., [2005], this issue of Structure) suggests how the survival of motor neuron (SMN) complex might facilitate the assembly of snRNPs that play important roles in pre-mRNA splicing.