Hemophilia A Resulting in Severe Hyperesthesia Due to Extraparenchymal Spinal Cord Hemorrhage in a Young Golden Retriever Puppy

• Published in: Veterinary sciences Vol. 9; no. 11; p. 638
• Main Authors: Lubbers, Charlotte, Beukers, Martijn, Bergknut, Niklas, Paes, Geert
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.11.2022; MDPI
• Subjects: Analgesia; Analgesics; Ataxia; Bleeding; Canals (anatomy); Case Report; Clotting; Coagulation factors; Computed tomography; Differential diagnosis; Dogs; Epidural; Fentanyl; Gene therapy; Hematoma; hematorrhachis; Hemophilia; hemophilia A; Hemorrhage; hyperesthesia; Intravenous administration; Magnetic resonance imaging; Muscles; Neurological diseases; Pain; Pain perception; Paralysis; Prothrombin; Quantitative genetics; Spinal cord; Thromboplastin; Ventilation; Vertebrae; Netherlands

A ten-week-old male Golden retriever puppy was presented with severe hyperesthesia, mild neurological deficits and episcleral bleeding. Clotting times showed a normal prothrombin time (PT) and prolonged activated partial thromboplastin time (aPPT). Computed tomography (CT) of the vertebral column sh...