Anticancer effect of celastrol on human triple negative breast cancer: Possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways - Shrivastava, Shweta; Jeengar, Manish Kumar; Reddy, V. Sudhakar; Reddy, G. Bhanuprakash; Naidu, V.G.M. (Experimental and molecular pathology, 2015)
Keywords: Apoptosis; Apoptosis - drug effects; Breast Neoplasms - metabolism; Celastrol; Cell Survival - drug effects; MCF-7 Cells; Mitochondria - drug effects; Mitochondria - metabolism; Mitochondrial dysfunction; Oxidative Stress; Phosphatidylinositol 3-Kinases - metabolism; PI3K/Akt; Proto-Oncogene Proteins c-akt - metabolism; Signal Transduction - drug effects; TNBC; Triterpenes - pharmacology; Triterpenes - toxicity; Oxidative stress; Mitochondrial dysfunction; TNBC; Celastrol; Apoptosis; PI3K/Akt