Investigation of anti-Toxoplasma gondii antibodies in patients with neoplasia

• Published in: Journal of medical microbiology Vol. 53; no. 12; pp. 1183 - 1186
• Main Authors: Yazar, Suleyman, Yaman, Ozan, Eser, Bulent, Altuntas, Fevzi, Kurnaz, Fatih, Sahin, Izzet
• Format: Journal Article
• Language: English
• Published: Reading Soc General Microbiol 01.12.2004; Society for General Microbiology
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibodies, Protozoan - blood; Antibodies, Protozoan - immunology; Biological and medical sciences; Female; Fundamental and applied biological sciences. Psychology; Humans; Immunocompromised Host; Immunoglobulin G - blood; Immunoglobulin G - immunology; Immunoglobulin M - blood; Immunoglobulin M - immunology; Infectious diseases; Male; Medical sciences; Microbiology; Middle Aged; Neoplasms - immunology; Toxoplasma - immunology; Toxoplasma gondii; Toxoplasmosis - epidemiology; Toxoplasmosis - immunology; Human; Protozoa; Apicomplexa; Toxoplasma gondii; Microbiology; Antibody
• ISSN: 0022-2615; 1473-5644
• DOI: 10.1099/jmm.0.45587-0

Departments of Parasitology 1 and Haematology 2 , Erciyes University Medical Faculty, 38039 Kayseri, Turkey Correspondence Süleyman Yazar syazar{at}erciyes.edu.tr Received January 9, 2004 Accepted August 10, 2004 This study aimed to determine the prevalence of anti- Toxoplasma gondii antibodies in patients with neoplasia. One hundred and eight patients with neoplasia and 108 healthy controls were studied for the presence of anti- T. gondii antibodies using a micro ELISA and peroxidase-labelled anti-human IgG (rabbit) and IgM (goat). Anti- T. gondii IgG antibodies were detected in 68 (63.0 %) patients and in 21 (19.4 %) of the controls, which was a statistically significant difference. In addition, anti- T. gondii IgM antibodies were detected in seven (6.5 %) patients and in one (0.9 %) control. A high percentage of positivity for Toxoplasma antibodies in patients with neoplasia was detected. Therefore, parasitological surveys of this patient group should be periodically performed.