Characterization of the Proinflammatory Cytokine Profile during Acute SARS-CoV-2 Infection in People with Human Immunodeficiency Virus

• Published in: Japanese Journal of Infectious Diseases Vol. 77; no. 6; pp. 301 - 310
• Main Authors: Anzurez, Alitzel, Runtuwene, Lucky, Dang, Thi Thu Thao, Nakayama-Hosoya, Kaori, Koga, Michiko, Yoshimura, Yukihiro, Sasaki, Hiroaki, Miyata, Nobuyuki, Miyazaki, Kazuhito, Takahashi, Yoshimasa, Suzuki, Tadaki, Yotsuyanagi, Hiroshi, Tachikawa, Natsuo, Matano, Tetsuro, Kawana-Tachikawa, Ai
• Format: Journal Article
• Language: English
• Published: Japan National Institute of Infectious Diseases 29.11.2024; Japan Science and Technology Agency
• Subjects: Adult; Aged; Antiretroviral agents; Antiretroviral therapy; Chronic infection; Coronaviruses; COVID-19; COVID-19 - blood; COVID-19 - immunology; Cytokines; Cytokines - blood; Female; HIV; HIV Infections - blood; HIV Infections - complications; HIV Infections - immunology; Human immunodeficiency virus; Humans; Immune response; Immune system; Infections; Inflammation; Inflammation - blood; innate responses; Intercellular adhesion molecule 1; IP-10 protein; Lipopolysaccharides; Male; Middle Aged; Plasma levels; proinflammatory cytokines; Respiratory diseases; SARS-CoV-2; SARS-CoV-2 - immunology; Severe acute respiratory syndrome coronavirus 2; Tumor necrosis factor-α; Viral diseases; α-Interferon; SARS-CoV-2; proinflammatory cytokines; innate responses; HIV

Persistent inflammation during chronic human immunodeficiency virus (HIV) infection may affect the immune response against severe acute respiratory syndrome-coronavirus 2 (SARS- CoV-2) infection. Plasma levels of multiple proinflammatory cytokines during acute SARS-CoV-2 infection were measured in p...