Clinical and Radiological Evaluations of COVID-19 Patients With Anosmia: Preliminary Report
To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID-19). Prospective non controlled study. Sixteen COVID-19 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through th...
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| Published in | The Laryngoscope Vol. 130; no. 11; p. 2526 |
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| Main Authors | , , , , , , , , |
| Format | Journal Article Web Resource |
| Language | English |
| Published |
United States
John Wiley & Sons, Inc
01.11.2020
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| Abstract | To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID-19).
Prospective non controlled study.
Sixteen COVID-19 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through the 22-item Sino-Nasal Outcome Test. Patients underwent psychophysical olfactory testing, olfactory cleft examination, and computed tomography (CT) scans.
Sixteen anosmic patients were included. The mean Sniffin' Sticks score was 4.6 ± 1.7. The majority of patients had no endoscopical abnormality, with a mean olfactory cleft endoscopy score of 0.6 ± 0.9. The olfactory clefts were opacified in three patients on the CT scan. The mean radiological olfactory cleft score was 0.7 ± 0.8. There were no significant correlations between clinical, radiological, and psychophysical olfactory testing.
The olfactory cleft of anosmic COVID-19 patients is free regarding endoscopic examination and imaging. The anosmia etiology is not related to edema of the olfactory cleft.
4 Laryngoscope, 130:2526-2531, 2020. |
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| AbstractList | Objective To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID‐19). Methods Sixteen COVID‐19 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through the sino‐nasal outcome test 22 (SNOT‐22). Patients underwent psychophysical olfactory testing, olfactory cleft examination and CT‐scan. Results Sixteen anosmic patients were included. The mean Sniffin'Sticks score was 4.6±1.7. The majority of patients had no endoscopical abnormality, with a mean olfactory cleft endoscopy score of 0.6±0.9. The olfactory clefts were opacified in 3 patients on the CT‐scan. The mean radiological olfactory cleft score was 0.7±0.8. There were no significant correlations between clinical, radiological and psychophysical olfactory testing. Conclusion The olfactory cleft of anosmic COVID‐19 patients is free regarding endoscopic examination and imaging. The anosmia etiology would be not related to edema of the olfactory cleft. To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID-19). Prospective non controlled study. Sixteen COVID-19 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through the 22-item Sino-Nasal Outcome Test. Patients underwent psychophysical olfactory testing, olfactory cleft examination, and computed tomography (CT) scans. Sixteen anosmic patients were included. The mean Sniffin' Sticks score was 4.6 ± 1.7. The majority of patients had no endoscopical abnormality, with a mean olfactory cleft endoscopy score of 0.6 ± 0.9. The olfactory clefts were opacified in three patients on the CT scan. The mean radiological olfactory cleft score was 0.7 ± 0.8. There were no significant correlations between clinical, radiological, and psychophysical olfactory testing. The olfactory cleft of anosmic COVID-19 patients is free regarding endoscopic examination and imaging. The anosmia etiology is not related to edema of the olfactory cleft. 4 Laryngoscope, 130:2526-2531, 2020. |
| Author | Lechien, Jerome R Michel, Justin Radulesco, Thomas Vaira, Luigi A Saussez, Sven Hopkins, Claire Sowerby, Leigh Chiesa-Estomba, Carlos M De Riu, Giacomo |
| Author_xml | – sequence: 1 givenname: Jerome R orcidid: 0000-0002-0845-0845 surname: Lechien fullname: Lechien, Jerome R organization: Department of Otolaryngology-Head and Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), Paris, France – sequence: 2 givenname: Justin surname: Michel fullname: Michel, Justin organization: Department of Oto-Rhino-Laryngology-Head and Neck Surgery, Aix Marseille University, APHM, IUSTI, La Conception University Hospital, Marseille, France – sequence: 3 givenname: Thomas surname: Radulesco fullname: Radulesco, Thomas organization: Department of Oto-Rhino-Laryngology-Head and Neck Surgery, Aix Marseille University, APHM, IUSTI, La Conception University Hospital, Marseille, France – sequence: 4 givenname: Carlos M orcidid: 0000-0001-9454-9464 surname: Chiesa-Estomba fullname: Chiesa-Estomba, Carlos M organization: Department of Otorhinolaryngology-Head and Neck Surgery, Hospital Universitario Donostia, San Sebastian, Spain – sequence: 5 givenname: Luigi A orcidid: 0000-0002-7789-145X surname: Vaira fullname: Vaira, Luigi A organization: Maxillofacial Surgery Unit, University Hospital of Sassari, Sassari, Italy – sequence: 6 givenname: Giacomo surname: De Riu fullname: De Riu, Giacomo organization: Maxillofacial Surgery Unit, University Hospital of Sassari, Sassari, Italy – sequence: 7 givenname: Leigh surname: Sowerby fullname: Sowerby, Leigh organization: Department of Otolaryngology-Head and Neck Surgery, University of Western Ontario, London, Ontario, Canada – sequence: 8 givenname: Claire surname: Hopkins fullname: Hopkins, Claire organization: Department of Otolaryngology, King's College, London, United Kingdom – sequence: 9 givenname: Sven surname: Saussez fullname: Saussez, Sven organization: Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Bruxelles, CHU Saint-Pierre, School of Medicine, Université Libre de Bruxelles, Brussels, Belgium |
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| Keywords | COVID-19 evaluation computed tomography scan anosmia taste coronavirus olfaction olfactory smell imaging |
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| Snippet | To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID-19).
Prospective non controlled... Objective To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID‐19). Methods Sixteen... |
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| SubjectTerms | Adult Anosmia - diagnostic imaging Anosmia - pathology Anosmia - virology COVID-19 - complications COVID-19 - diagnostic imaging COVID-19 - pathology Female Humans Male Middle Aged Olfaction Disorders - diagnostic imaging Olfaction Disorders - pathology Olfaction Disorders - virology Prospective Studies SARS-CoV-2 Tomography, X-Ray Computed |
| Title | Clinical and Radiological Evaluations of COVID-19 Patients With Anosmia: Preliminary Report |
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