Clinical and Radiological Evaluations of COVID-19 Patients With Anosmia: Preliminary Report

To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID-19). Prospective non controlled study. Sixteen COVID-19 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through th...

Full description

Saved in:
Bibliographic Details
Published inThe Laryngoscope Vol. 130; no. 11; p. 2526
Main Authors Lechien, Jerome R, Michel, Justin, Radulesco, Thomas, Chiesa-Estomba, Carlos M, Vaira, Luigi A, De Riu, Giacomo, Sowerby, Leigh, Hopkins, Claire, Saussez, Sven
Format Journal Article Web Resource
LanguageEnglish
Published United States John Wiley & Sons, Inc 01.11.2020
Subjects
Adult
Anosmia - diagnostic imaging
Anosmia - pathology
Anosmia - virology
COVID-19 - complications
COVID-19 - diagnostic imaging
COVID-19 - pathology
Female
Humans
Male
Middle Aged
Olfaction Disorders - diagnostic imaging
Olfaction Disorders - pathology
Olfaction Disorders - virology
Prospective Studies
SARS-CoV-2
Tomography, X-Ray Computed
COVID-19
evaluation
computed tomography scan
anosmia
taste
coronavirus
olfaction
olfactory
smell
imaging
Online AccessGet full text

Cover

More Information
Summary:To investigate clinical and radiological features of olfactory clefts of patients with mild coronavirus disease 2019 (COVID-19). Prospective non controlled study. Sixteen COVID-19 patients were recruited. The epidemiological and clinical data were extracted. Nasal complaints were assessed through the 22-item Sino-Nasal Outcome Test. Patients underwent psychophysical olfactory testing, olfactory cleft examination, and computed tomography (CT) scans. Sixteen anosmic patients were included. The mean Sniffin' Sticks score was 4.6 ± 1.7. The majority of patients had no endoscopical abnormality, with a mean olfactory cleft endoscopy score of 0.6 ± 0.9. The olfactory clefts were opacified in three patients on the CT scan. The mean radiological olfactory cleft score was 0.7 ± 0.8. There were no significant correlations between clinical, radiological, and psychophysical olfactory testing. The olfactory cleft of anosmic COVID-19 patients is free regarding endoscopic examination and imaging. The anosmia etiology is not related to edema of the olfactory cleft. 4 Laryngoscope, 130:2526-2531, 2020.
ISSN:1531-4995
DOI:10.1002/lary.28993