Aortic Valve Calcification: Determinants and Progression in the Population

• Published in: Arteriosclerosis, thrombosis, and vascular biology Vol. 27; no. 3; pp. 642 - 648
• Main Authors: Messika-Zeitoun, David, Bielak, Lawrence F., Peyser, Patricia A., Sheedy, Patrick F., Turner, Stephen T., Nkomo, Vuyisile T., Breen, Jerome F., Maalouf, Joseph, Scott, Christopher, Tajik, A Jamil, Enriquez-Sarano, Maurice
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA American Heart Association, Inc 01.03.2007; Hagerstown, MD Lippincott
• Subjects: Age Distribution; Aged; Aortic Valve; Atherosclerosis (general aspects, experimental research); Biological and medical sciences; Blood and lymphatic vessels; Calcinosis - diagnosis; Calcinosis - epidemiology; Cardiology. Vascular system; Cardiovascular system; Causality; Cohort Studies; Comorbidity; Disease Progression; Diseases of the aorta; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Echocardiography, Doppler; Female; Follow-Up Studies; Heart Valve Diseases - diagnosis; Heart Valve Diseases - epidemiology; Humans; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; Multivariate Analysis; Prevalence; Probability; Prospective Studies; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Risk Assessment; Severity of Illness Index; Sex Distribution; Tomography, X-Ray Computed; Vascular disease; computed tomography; Aortic valve calcification; Cardiac valvular disease; Atherosclerosis; Cardiovascular disease; Computerized axial tomography; calcification; Epidemiology; Aortic valve

BACKGROUND—Aortic valve calcification (AVC) is considered degenerative. Recent data suggested links to atherosclerosis or coronary disease (CAD). METHODS AND RESULTS—AVC and coronary artery calcifications (CAC) were prospectively assessed by Electron-Beam-Computed-Tomography in 262 population-based...