Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus - Webb, Ryan; Wren, Jonathan D.; Jeffries, Matlock; Kelly, Jennifer A.; Kaufman, Kenneth M.; Tang, Yuhong; Frank, Mark Barton; Merrill, Joan; Kimberly, Robert P.; Edberg, Jeffrey C.; Ramsey‐Goldman, Rosalind; Petri, Michelle; et al. (Arthritis and rheumatism, 2009)
Keywords: B-Lymphocytes - cytology; B-Lymphocytes - physiology; Biological and medical sciences; Cells, Cultured; Cohort Studies; Diseases of the osteoarticular system; Epigenesis, Genetic; Female; Gene Frequency; Genetic Predisposition to Disease - ethnology; Genetic Variation; Haplotypes; Humans; Lupus Erythematosus, Systemic - ethnology; Lupus Erythematosus, Systemic - genetics; Male; Medical sciences; MEDICIN; MEDICINE; Methyl-CpG-Binding Protein 2 - genetics; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; White People - statistics & numerical data; Human; Immunopathology; Connective tissue disease; Skin disease; Systemic lupus erythematosus; Transcription; Systemic disease; Rheumatology; Autoimmune disease; Gene expression