Gut feelings: the microbiota-gut-brain axis on steroids

• Published in: American journal of physiology: Gastrointestinal and liver physiology Vol. 322; no. 1; pp. G1 - G20
• Main Authors: So, Sik Yu, Savidge, Tor C.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.01.2022
• Series: Microbiome-Based Therapeutics and Their Physiological Effects
• Subjects: Animals; Brain - physiology; Brain-Gut Axis - physiology; Dementia disorders; Digestive system; Emotions - physiology; Enteric nervous system; Enteric Nervous System - physiology; Gastrointestinal Microbiome - physiology; Gastrointestinal tract; Gut-brain axis; Humans; Intestinal microflora; Intestine; Microbiota; Nervous system; Neurological diseases; Neurosteroids; Receptor mechanisms; Steroid hormones; Steroids; Steroids - metabolism; Theme; neuroactive steroids; steroids; nervous system; gut microbiota; gut-brain axis

The intricate connection between central and enteric nervous systems is well established with emerging evidence linking gut microbiota function as a significant new contributor to gut-brain axis signaling. Several microbial signals contribute to altered gut-brain communications, with steroids repres...