A window of vulnerability: Impaired fear extinction in adolescence

• Published in: Neurobiology of learning and memory Vol. 113; pp. 90 - 100
• Main Authors: Baker, Kathryn D., Den, Miriam L., Graham, Bronwyn M., Richardson, Rick
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2014; Elsevier BV
• Subjects: Adolescence; Adolescent; Adolescent Development - physiology; Amygdala - growth & development; Amygdala - physiology; Amygdala - physiopathology; Animals; Extinction; Extinction, Psychological - physiology; Fear; Fear & phobias; Fear - physiology; Functional connectivity; Humans; Neurobiology; Prefrontal Cortex - growth & development; Prefrontal Cortex - physiology; Prefrontal Cortex - physiopathology; Stress; Stress, Psychological - physiopathology; Teenagers; Functional connectivity; Fear; Adolescence; Extinction; Stress

There have been significant advances made towards understanding the processes mediating extinction of learned fear. However, despite being of clear theoretical and clinical significance, very few studies have examined fear extinction in adolescence, which is often described as a developmental window...