Effect of uncertainties in musculoskeletal modeling inputs on sensitivity of knee joint finite element simulations

• Published in: Medical engineering & physics Vol. 138; p. 104313
• Main Authors: Jahangir, Sana, Bosch, Will, Esrafilian, Amir, Mononen, Mika E., Tanska, Petri, Stenroth, Lauri, Henriksen, Marius, Alkjær, Tine, Korhonen, Rami K.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.04.2025
• Subjects: Adult; Biomechanical Phenomena; Finite Element Analysis; Finite element modeling; Gait; Humans; Knee joint; Knee Joint - physiology; Male; Mechanical Phenomena; Modeling assumptions; Models, Biological; Musculoskeletal modeling; Personalized gait data; Uncertainty; Knee joint; Musculoskeletal modeling; Finite element modeling; Modeling assumptions; Personalized gait data

•Analyzed the impact of various modeling assumptions on knee joint mechanics.•Constructed and tested five musculoskeletal models per subject plus a reference model.•Compared personalized gait inputs with literature-based non-personalized inputs.•Found up to 61% variation in finite element parameters...