Epidemiology of Candidemia and Antifungal Susceptibility in Invasive Candida Species in the Asia-Pacific Region

• Published in: Future microbiology Vol. 11; no. 11; pp. 1461 - 1477
• Main Authors: Wang, He, Xu, Ying-Chun, Hsueh, Po-Ren
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.10.2016
• Subjects: Antifungal agents; Antifungal Agents - therapeutic use; Asia - epidemiology; Azoles - therapeutic use; Candida; Candida - drug effects; Candida - isolation & purification; Candida - pathogenicity; Candida albicans; Candida albicans - drug effects; Candida albicans - pathogenicity; Candida glabrata - drug effects; Candida glabrata - isolation & purification; Candida glabrata - pathogenicity; Candida tropicalis - drug effects; Candida tropicalis - isolation & purification; Candida tropicalis - pathogenicity; Candidemia; Candidemia - drug therapy; Candidemia - epidemiology; Candidemia - microbiology; Candidiasis; Candidiasis, Invasive - drug therapy; Candidiasis, Invasive - epidemiology; Candidiasis, Invasive - microbiology; Drug Resistance, Fungal - drug effects; Echinocandins; Echinocandins - therapeutic use; Epidemiology; Etiology; Fluconazole; Fluconazole - therapeutic use; Hematology; Hospitals; Humans; Incidence; Infections; Intensive care; Itraconazole; Itraconazole - therapeutic use; Lipopeptides - therapeutic use; Micafungin; Microbial Sensitivity Tests; Mortality; Patients; Phenotype; Phenotypes; Prevalence; Species; Trends; Voriconazole; Voriconazole - therapeutic use; Singapore; Asia; Asia-Pacific region; China; Taiwan; Thailand; India; invasive candidiasis; Asia-Pacific region; candidemia; antifungal susceptibility

In the Asia-Pacific region, Candida albicans is the predominant Candida species causing invasive candidiasis/candidemia in Australia, Japan, Korea, Hong Kong, Malaysia, Singapore and Thailand whereas C. tropicalis is the most frequently encountered Candida species in Pakistan and India. Invasive iso...