Nuclear magnetic resonance based metabolomics and liver diseases: Recent advances and future clinical applications

• Published in: World journal of gastroenterology : WJG Vol. 22; no. 1; pp. 417 - 426
• Main Author: Amathieu, Roland
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Co. Limited 07.01.2016; Baishideng Publishing Group Inc
• Subjects: Carcinoma, Hepatocellular - diagnosis; Carcinoma, Hepatocellular - metabolism; Chemical and Drug Induced Liver Injury - diagnosis; Chemical and Drug Induced Liver Injury - metabolism; Hepatitis C, Chronic - diagnosis; Hepatitis C, Chronic - metabolism; Hepatitis, Autoimmune - diagnosis; Hepatitis, Autoimmune - metabolism; Humans; Life Sciences; Liver Cirrhosis - diagnosis; Liver Cirrhosis - metabolism; Liver Diseases - diagnosis; Liver Diseases - metabolism; Liver Failure, Acute - diagnosis; Liver Failure, Acute - metabolism; Liver Neoplasms - diagnosis; Liver Neoplasms - metabolism; Liver Transplantation; Metabolomics - methods; Metabolomics - trends; Minireviews; Proton Magnetic Resonance Spectroscopy - methods; Cirrhosis; Metabolomics; Liver diseases; In vitro nuclear magnetic resonance spectroscopy

Metabolomics is defined as the quantitative measurement of the dynamic multiparametric metabolic response of living systems to pathophysiological stimuli or genetic modification. It is an "omics" technique that is situated downstream of genomics, transcriptomics and proteomics. Metabolomic...