Methods in Lung Microbiome Research

• Published in: American journal of respiratory cell and molecular biology Vol. 62; no. 3; pp. 283 - 299
• Main Authors: Carney, Sharon M., Clemente, Jose C., Cox, Michael J., Dickson, Robert P., Huang, Yvonne J., Kitsios, Georgios D., Kloepfer, Kirsten M., Leung, Janice M., LeVan, Tricia D., Molyneaux, Philip L., Moore, Bethany B., O’Dwyer, David N., Segal, Leopoldo N., Garantziotis, Stavros
• Format: Journal Article
• Language: English
• Published: United States American Thoracic Society 01.03.2020
• Subjects: Animals; Anti-Infective Agents - pharmacology; Bacterial Typing Techniques; Body Fluids - microbiology; Breath Tests; Clinical trials; Dysbiosis - microbiology; Environmental Exposure; Epidemiologic Methods; Host Microbial Interactions; Humans; Immune response; Lung - microbiology; Lung cancer; Lungs; Metagenomics - methods; Microbiological Techniques; Microbiomes; Microbiota - drug effects; Models, Animal; Models, Biological; Reproducibility of Results; Research methodology; Respiratory System - microbiology; Specimen Handling - methods; Sputum - microbiology; Translational Research, Biomedical; Translational Review; Whole Genome Sequencing; lung; analysis; microbiome; methods; reporting

The lung microbiome is associated with host immune response and health outcomes in experimental models and patient cohorts. Lung microbiome research is increasing in volume and scope; however, there are no established guidelines for study design, conduct, and reporting of lung microbiome studies. St...