Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells - Porichis, Filippos; Hart, Meghan G; Massa, Alexandra; Everett, Holly L; Morou, Antigoni; Richard, Jonathan; Brassard, Nathalie; Veillette, Maxime; Hassan, Muska; Ly, Ngoc Le; Routy, Jean-Pierre; Freeman, Gordon J; et al. (The Journal of immunology (1950), 2018)
Keywords: Adaptive immunity; Anti-Retroviral Agents - pharmacology; Antiretroviral therapy; Cancer; CD4 antigen; CD4-Positive T-Lymphocytes - drug effects; CD4-Positive T-Lymphocytes - immunology; Cell Line, Tumor; Cohort Studies; Cytokines; Degranulation; HIV; HIV Infections - drug therapy; HIV Infections - immunology; HIV-1 - drug effects; HIV-1 - immunology; Human immunodeficiency virus; Humans; Immune checkpoint; Immunomodulation; Infections; Innate immunity; Interferon-gamma - immunology; Interleukin 10; Interleukin 12; Interleukin 2; Interleukin-10 - immunology; Interleukin-2 - immunology; K562 Cells; Killer Cells, Natural - drug effects; Killer Cells, Natural - immunology; Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - immunology; Leukocytes, Mononuclear - virology; Lymphocytes; Lymphocytes T; Natural killer cells; PD-1 protein; Peripheral blood mononuclear cells; Programmed Cell Death 1 Receptor - immunology; Viral Load - drug effects; Viral Load - immunology; Viremia; γ-Interferon