Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history
Cannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies in Asia. Over the course of time different parts of the plant have been utilized for therapeutic and recreational purposes, for instance, extraction of h...
Saved in:
| Published in | Journal of ethnopharmacology Vol. 227; pp. 300 - 315 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Ireland
Elsevier B.V
05.12.2018
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Cannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies in Asia. Over the course of time different parts of the plant have been utilized for therapeutic and recreational purposes, for instance, extraction of healing oils from seed, or the use of inflorescences for their psychoactive effects. The key psychoactive constituent in C. sativa is called Δ-9-tetrahydrocannabinol (D9-THC). The endocannabinoid system seems to be phylogenetically ancient, as it was present in the most primitive vertebrates with a neuronal network. N-arachidonoylethanolamine (AEA) and 2-arachidonoyl glycerol (2-AG) are the main endocannabinoids ligands present in the animal kingdom, and the main endocannabinoid receptors are cannabinoid type-1 (CB1) receptor and cannabinoid type-2 (CB2) receptor.
The review aims to provide a critical and comprehensive evaluation, from the ancient times to our days, of the ethnological, botanical, chemical and pharmacological aspects of C. sativa, with a vision for promoting further pharmaceutical research to explore its complete potential as a therapeutic agent.
This study was performed by reviewing in extensive details the studies on historical significance and ethnopharmacological applications of C. sativa by using international scientific databases, books, Master’s and Ph.D. dissertations and government reports. In addition, we also try to gather relevant information from large regional as well as global unpublished resources. In addition, the plant taxonomy was validated using certified databases such as Medicinal Plant Names Services (MPNS) and The Plant List.
A detailed comparative analysis of the available resources for C. sativa confirmed its origin and traditional spiritual, household and therapeutic uses and most importantly its popularity as a recreational drug. The result of several studies suggested a deeper involvement of phytocannabinoids (the key compounds in C. sativa) in several others central and peripheral pathophysiological mechanisms such as food intake, inflammation, pain, colitis, sleep disorders, neurological and psychiatric illness. However, despite their numerous medicinal benefits, they are still considered as a menace to the society and banned throughout the world, except for few countries. We believe that this review will help lay the foundation for promoting exhaustive pharmacological and pharmaceutical studies in order to better understand the clinical relevance and applications of non-psychoactive cannabinoids in the prevention and treatment of life-threatening diseases and help to improve the legal status of C. sativa.
[Display omitted] |
|---|---|
| AbstractList | Cannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies in Asia. Over the course of time different parts of the plant have been utilized for therapeutic and recreational purposes, for instance, extraction of healing oils from seed, or the use of inflorescences for their psychoactive effects. The key psychoactive constituent in C. sativa is called Δ-9-tetrahydrocannabinol (D9-THC). The endocannabinoid system seems to be phylogenetically ancient, as it was present in the most primitive vertebrates with a neuronal network. N-arachidonoylethanolamine (AEA) and 2-arachidonoyl glycerol (2-AG) are the main endocannabinoids ligands present in the animal kingdom, and the main endocannabinoid receptors are cannabinoid type-1 (CB1) receptor and cannabinoid type-2 (CB2) receptor.
The review aims to provide a critical and comprehensive evaluation, from the ancient times to our days, of the ethnological, botanical, chemical and pharmacological aspects of C. sativa, with a vision for promoting further pharmaceutical research to explore its complete potential as a therapeutic agent.
This study was performed by reviewing in extensive details the studies on historical significance and ethnopharmacological applications of C. sativa by using international scientific databases, books, Master's and Ph.D. dissertations and government reports. In addition, we also try to gather relevant information from large regional as well as global unpublished resources. In addition, the plant taxonomy was validated using certified databases such as Medicinal Plant Names Services (MPNS) and The Plant List.
A detailed comparative analysis of the available resources for C. sativa confirmed its origin and traditional spiritual, household and therapeutic uses and most importantly its popularity as a recreational drug. The result of several studies suggested a deeper involvement of phytocannabinoids (the key compounds in C. sativa) in several others central and peripheral pathophysiological mechanisms such as food intake, inflammation, pain, colitis, sleep disorders, neurological and psychiatric illness. However, despite their numerous medicinal benefits, they are still considered as a menace to the society and banned throughout the world, except for few countries. We believe that this review will help lay the foundation for promoting exhaustive pharmacological and pharmaceutical studies in order to better understand the clinical relevance and applications of non-psychoactive cannabinoids in the prevention and treatment of life-threatening diseases and help to improve the legal status of C. sativa. Cannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies in Asia. Over the course of time different parts of the plant have been utilized for therapeutic and recreational purposes, for instance, extraction of healing oils from seed, or the use of inflorescences for their psychoactive effects. The key psychoactive constituent in C. sativa is called Δ-9-tetrahydrocannabinol (D9-THC). The endocannabinoid system seems to be phylogenetically ancient, as it was present in the most primitive vertebrates with a neuronal network. N-arachidonoylethanolamine (AEA) and 2-arachidonoyl glycerol (2-AG) are the main endocannabinoids ligands present in the animal kingdom, and the main endocannabinoid receptors are cannabinoid type-1 (CB1) receptor and cannabinoid type-2 (CB2) receptor.The review aims to provide a critical and comprehensive evaluation, from the ancient times to our days, of the ethnological, botanical, chemical and pharmacological aspects of C. sativa, with a vision for promoting further pharmaceutical research to explore its complete potential as a therapeutic agent.This study was performed by reviewing in extensive details the studies on historical significance and ethnopharmacological applications of C. sativa by using international scientific databases, books, Master’s and Ph.D. dissertations and government reports. In addition, we also try to gather relevant information from large regional as well as global unpublished resources. In addition, the plant taxonomy was validated using certified databases such as Medicinal Plant Names Services (MPNS) and The Plant List.A detailed comparative analysis of the available resources for C. sativa confirmed its origin and traditional spiritual, household and therapeutic uses and most importantly its popularity as a recreational drug. The result of several studies suggested a deeper involvement of phytocannabinoids (the key compounds in C. sativa) in several others central and peripheral pathophysiological mechanisms such as food intake, inflammation, pain, colitis, sleep disorders, neurological and psychiatric illness. However, despite their numerous medicinal benefits, they are still considered as a menace to the society and banned throughout the world, except for few countries. We believe that this review will help lay the foundation for promoting exhaustive pharmacological and pharmaceutical studies in order to better understand the clinical relevance and applications of non-psychoactive cannabinoids in the prevention and treatment of life-threatening diseases and help to improve the legal status of C. sativa. Cannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies in Asia. Over the course of time different parts of the plant have been utilized for therapeutic and recreational purposes, for instance, extraction of healing oils from seed, or the use of inflorescences for their psychoactive effects. The key psychoactive constituent in C. sativa is called Δ-9-tetrahydrocannabinol (D9-THC). The endocannabinoid system seems to be phylogenetically ancient, as it was present in the most primitive vertebrates with a neuronal network. N-arachidonoylethanolamine (AEA) and 2-arachidonoyl glycerol (2-AG) are the main endocannabinoids ligands present in the animal kingdom, and the main endocannabinoid receptors are cannabinoid type-1 (CB1) receptor and cannabinoid type-2 (CB2) receptor.ETHNOPHARMACOLOGICAL RELEVANCECannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies in Asia. Over the course of time different parts of the plant have been utilized for therapeutic and recreational purposes, for instance, extraction of healing oils from seed, or the use of inflorescences for their psychoactive effects. The key psychoactive constituent in C. sativa is called Δ-9-tetrahydrocannabinol (D9-THC). The endocannabinoid system seems to be phylogenetically ancient, as it was present in the most primitive vertebrates with a neuronal network. N-arachidonoylethanolamine (AEA) and 2-arachidonoyl glycerol (2-AG) are the main endocannabinoids ligands present in the animal kingdom, and the main endocannabinoid receptors are cannabinoid type-1 (CB1) receptor and cannabinoid type-2 (CB2) receptor.The review aims to provide a critical and comprehensive evaluation, from the ancient times to our days, of the ethnological, botanical, chemical and pharmacological aspects of C. sativa, with a vision for promoting further pharmaceutical research to explore its complete potential as a therapeutic agent.AIM OF THE STUDYThe review aims to provide a critical and comprehensive evaluation, from the ancient times to our days, of the ethnological, botanical, chemical and pharmacological aspects of C. sativa, with a vision for promoting further pharmaceutical research to explore its complete potential as a therapeutic agent.This study was performed by reviewing in extensive details the studies on historical significance and ethnopharmacological applications of C. sativa by using international scientific databases, books, Master's and Ph.D. dissertations and government reports. In addition, we also try to gather relevant information from large regional as well as global unpublished resources. In addition, the plant taxonomy was validated using certified databases such as Medicinal Plant Names Services (MPNS) and The Plant List.MATERIALS AND METHODSThis study was performed by reviewing in extensive details the studies on historical significance and ethnopharmacological applications of C. sativa by using international scientific databases, books, Master's and Ph.D. dissertations and government reports. In addition, we also try to gather relevant information from large regional as well as global unpublished resources. In addition, the plant taxonomy was validated using certified databases such as Medicinal Plant Names Services (MPNS) and The Plant List.A detailed comparative analysis of the available resources for C. sativa confirmed its origin and traditional spiritual, household and therapeutic uses and most importantly its popularity as a recreational drug. The result of several studies suggested a deeper involvement of phytocannabinoids (the key compounds in C. sativa) in several others central and peripheral pathophysiological mechanisms such as food intake, inflammation, pain, colitis, sleep disorders, neurological and psychiatric illness. However, despite their numerous medicinal benefits, they are still considered as a menace to the society and banned throughout the world, except for few countries. We believe that this review will help lay the foundation for promoting exhaustive pharmacological and pharmaceutical studies in order to better understand the clinical relevance and applications of non-psychoactive cannabinoids in the prevention and treatment of life-threatening diseases and help to improve the legal status of C. sativa.RESULTS AND CONCLUSIONSA detailed comparative analysis of the available resources for C. sativa confirmed its origin and traditional spiritual, household and therapeutic uses and most importantly its popularity as a recreational drug. The result of several studies suggested a deeper involvement of phytocannabinoids (the key compounds in C. sativa) in several others central and peripheral pathophysiological mechanisms such as food intake, inflammation, pain, colitis, sleep disorders, neurological and psychiatric illness. However, despite their numerous medicinal benefits, they are still considered as a menace to the society and banned throughout the world, except for few countries. We believe that this review will help lay the foundation for promoting exhaustive pharmacological and pharmaceutical studies in order to better understand the clinical relevance and applications of non-psychoactive cannabinoids in the prevention and treatment of life-threatening diseases and help to improve the legal status of C. sativa. Cannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies in Asia. Over the course of time different parts of the plant have been utilized for therapeutic and recreational purposes, for instance, extraction of healing oils from seed, or the use of inflorescences for their psychoactive effects. The key psychoactive constituent in C. sativa is called Δ-9-tetrahydrocannabinol (D9-THC). The endocannabinoid system seems to be phylogenetically ancient, as it was present in the most primitive vertebrates with a neuronal network. N-arachidonoylethanolamine (AEA) and 2-arachidonoyl glycerol (2-AG) are the main endocannabinoids ligands present in the animal kingdom, and the main endocannabinoid receptors are cannabinoid type-1 (CB1) receptor and cannabinoid type-2 (CB2) receptor. The review aims to provide a critical and comprehensive evaluation, from the ancient times to our days, of the ethnological, botanical, chemical and pharmacological aspects of C. sativa, with a vision for promoting further pharmaceutical research to explore its complete potential as a therapeutic agent. This study was performed by reviewing in extensive details the studies on historical significance and ethnopharmacological applications of C. sativa by using international scientific databases, books, Master’s and Ph.D. dissertations and government reports. In addition, we also try to gather relevant information from large regional as well as global unpublished resources. In addition, the plant taxonomy was validated using certified databases such as Medicinal Plant Names Services (MPNS) and The Plant List. A detailed comparative analysis of the available resources for C. sativa confirmed its origin and traditional spiritual, household and therapeutic uses and most importantly its popularity as a recreational drug. The result of several studies suggested a deeper involvement of phytocannabinoids (the key compounds in C. sativa) in several others central and peripheral pathophysiological mechanisms such as food intake, inflammation, pain, colitis, sleep disorders, neurological and psychiatric illness. However, despite their numerous medicinal benefits, they are still considered as a menace to the society and banned throughout the world, except for few countries. We believe that this review will help lay the foundation for promoting exhaustive pharmacological and pharmaceutical studies in order to better understand the clinical relevance and applications of non-psychoactive cannabinoids in the prevention and treatment of life-threatening diseases and help to improve the legal status of C. sativa. [Display omitted] |
| Author | Memo, Maurizio Maccarinelli, Giuseppina Premoli, Marika Kumar, Amit Bonini, Sara Anna Tambaro, Simone Mastinu, Andrea |
| Author_xml | – sequence: 1 givenname: Sara Anna surname: Bonini fullname: Bonini, Sara Anna organization: Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Brescia, Italy – sequence: 2 givenname: Marika surname: Premoli fullname: Premoli, Marika organization: Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Brescia, Italy – sequence: 3 givenname: Simone surname: Tambaro fullname: Tambaro, Simone organization: Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden – sequence: 4 givenname: Amit surname: Kumar fullname: Kumar, Amit organization: Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Clinical Geriatrics, Karolinska Institutet, Huddinge, Sweden – sequence: 5 givenname: Giuseppina surname: Maccarinelli fullname: Maccarinelli, Giuseppina organization: Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Brescia, Italy – sequence: 6 givenname: Maurizio surname: Memo fullname: Memo, Maurizio organization: Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Brescia, Italy – sequence: 7 givenname: Andrea surname: Mastinu fullname: Mastinu, Andrea email: andrea.mastinu@unibs.it organization: Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Brescia, Italy |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30205181$$D View this record in MEDLINE/PubMed http://kipublications.ki.se/Default.aspx?queryparsed=id:139374840$$DView record from Swedish Publication Index |
| BookMark | eNqNkc1u3CAUhVGVqpmkfYBuKpbd2LlgbHC7ikb9iRSpm3aNMLmOmXrABWZGefsQzaSLLqKuQEffuVzOuSBnPngk5D2DmgHrrjb1BpeaA1M19DWAeEVWTEleyVY2Z2QFjVSVkoKdk4uUNgAgmYA35LwBDi1TbEVwbbw3g0s0mez25hO9pjZsl4gT-uT2SDFPPiyTiVtjwxzunTUzjbh3eKBhpIZu8c5Z54u6zMZnenB5KvIc_D2dXMohPrwlr0czJ3x3Oi_Jr69ffq6_V7c_vt2sr28rK7jIleGoOEgrQTFQI2fSCNYKFF2rjLKNHBG7dhhQKAsosG-bDiWTQgi0SjbNJamOc9MBl92gl-i2Jj7oYJw-Sb_LDbVQbSfbwn888ksMf3aYst66ZHEu_8CwS5qz8gKTXd_8Bwq859C3UNAPJ3Q3lHD-bvGcegHkEbAxpBRx1NblEn_wORo3awb6qV-90aVf_dSvhl6XfouT_eN8Hv6S5_PRgyX5UlvUyTr0ttQW0WZ9F9wL7kc-Nb03 |
| CitedBy_id | crossref_primary_10_1142_S2737416523500242 crossref_primary_10_1089_can_2022_0076 crossref_primary_10_3390_brainsci12111582 crossref_primary_10_1016_j_indcrop_2023_116562 crossref_primary_10_1093_jpp_rgae101 crossref_primary_10_1016_j_jep_2018_11_025 crossref_primary_10_1371_journal_pone_0260660 crossref_primary_10_3390_nu11051010 crossref_primary_10_3390_separations11040106 crossref_primary_10_1021_acs_jnatprod_4c00212 crossref_primary_10_3390_antibiotics13111023 crossref_primary_10_3390_molecules28020638 crossref_primary_10_3390_ph15070836 crossref_primary_10_3389_fpls_2020_580621 crossref_primary_10_2478_amb_2021_0005 crossref_primary_10_3389_fvets_2022_977457 crossref_primary_10_1371_journal_pone_0272893 crossref_primary_10_1016_j_jpsychires_2021_02_048 crossref_primary_10_1016_j_phyplu_2024_100573 crossref_primary_10_3390_ph16081149 crossref_primary_10_48022_mbl_2303_03012 crossref_primary_10_3390_molecules25245792 crossref_primary_10_3390_molecules27103171 crossref_primary_10_54751_revistafoco_v17n9_146 crossref_primary_10_1016_j_leukres_2020_106389 crossref_primary_10_1016_j_supflu_2020_104898 crossref_primary_10_3390_agriengineering7010001 crossref_primary_10_1016_j_aca_2021_339020 crossref_primary_10_1007_s11101_021_09794_w crossref_primary_10_3390_plants11182364 crossref_primary_10_3389_fpls_2019_01265 crossref_primary_10_1089_can_2021_0237 crossref_primary_10_3390_ph17121644 crossref_primary_10_24017_Science_2022_1_12 crossref_primary_10_1089_can_2021_0110 crossref_primary_10_3390_ph15080976 crossref_primary_10_3390_molecules25184078 crossref_primary_10_3390_w14233842 crossref_primary_10_3390_molecules24152726 crossref_primary_10_1124_pharmrev_120_000046 crossref_primary_10_3390_separations8120231 crossref_primary_10_1016_j_bcab_2022_102327 crossref_primary_10_1016_j_jarmap_2023_100476 crossref_primary_10_1002_jat_4646 crossref_primary_10_3390_molecules24081517 crossref_primary_10_3390_ijms22052454 crossref_primary_10_1021_acs_jafc_4c01286 crossref_primary_10_1016_j_jpba_2022_115037 crossref_primary_10_31015_jaefs_2021_4_32 crossref_primary_10_2174_1389201024666230508142114 crossref_primary_10_1016_j_phrs_2020_105302 crossref_primary_10_3390_molecules26144113 crossref_primary_10_3390_medicina60060954 crossref_primary_10_1002_jat_4409 crossref_primary_10_1007_s11419_022_00625_x crossref_primary_10_52711_0974_360X_2024_00065 crossref_primary_10_1016_j_fsigss_2022_10_004 crossref_primary_10_1089_can_2021_0017 crossref_primary_10_3390_biom12101462 crossref_primary_10_3390_molecules28237686 crossref_primary_10_3390_medicina56050237 crossref_primary_10_3390_ph17111549 crossref_primary_10_1007_s13399_021_01751_z crossref_primary_10_1002_slct_202204079 crossref_primary_10_3390_biomedicines13020520 crossref_primary_10_3390_molecules25061381 crossref_primary_10_1126_sciadv_abg2286 crossref_primary_10_3390_molecules26237216 crossref_primary_10_1016_j_indcrop_2024_119090 crossref_primary_10_3390_life12091394 crossref_primary_10_3390_molecules28093806 crossref_primary_10_1042_NS20200080 crossref_primary_10_3390_molecules27072339 crossref_primary_10_13005_ojc_390604 crossref_primary_10_3390_molecules24050918 crossref_primary_10_1016_j_aca_2022_340452 crossref_primary_10_1089_can_2022_0125 crossref_primary_10_1016_j_jddst_2023_104282 crossref_primary_10_1080_1061186X_2022_2056188 crossref_primary_10_1186_s42238_025_00270_2 crossref_primary_10_3390_molecules24183353 crossref_primary_10_3390_agronomy13030931 crossref_primary_10_1016_j_hermed_2023_100798 crossref_primary_10_3390_molecules23123320 crossref_primary_10_1016_j_bioorg_2024_107775 crossref_primary_10_3389_fpsyt_2022_837946 crossref_primary_10_1007_s00425_019_03138_x crossref_primary_10_1016_j_indcrop_2023_117860 crossref_primary_10_1016_j_indcrop_2023_117861 crossref_primary_10_1007_s42823_023_00519_x crossref_primary_10_2174_1389203724666230830125423 crossref_primary_10_1111_bcpt_13997 crossref_primary_10_3390_tropicalmed9020035 crossref_primary_10_1016_j_arr_2020_101209 crossref_primary_10_1038_s41598_024_80857_6 crossref_primary_10_1021_acs_jnatprod_4c00608 crossref_primary_10_1007_s00580_021_03200_9 crossref_primary_10_3390_plants10102078 crossref_primary_10_1016_j_molliq_2021_118318 crossref_primary_10_1007_s44395_025_00003_7 crossref_primary_10_3390_v12080875 crossref_primary_10_1016_j_jep_2023_116839 crossref_primary_10_2174_1389201020666190618111252 crossref_primary_10_3390_ph17121702 crossref_primary_10_1515_chem_2023_0214 crossref_primary_10_1080_07352689_2024_2410145 crossref_primary_10_1177_10781552241239006 crossref_primary_10_3390_molecules24071227 crossref_primary_10_1016_j_phrs_2020_104822 crossref_primary_10_1007_s42535_024_01077_x crossref_primary_10_1016_j_jsps_2023_101881 crossref_primary_10_3390_molecules27092797 crossref_primary_10_57582_IJBF_220203_084 crossref_primary_10_1371_journal_pone_0261900 crossref_primary_10_52965_001c_35848 crossref_primary_10_1016_j_envres_2023_117763 crossref_primary_10_1016_j_heliyon_2023_e22679 crossref_primary_10_1016_j_indcrop_2023_117031 crossref_primary_10_1021_acschemneuro_3c00176 crossref_primary_10_1016_j_bmcl_2021_128442 crossref_primary_10_3389_fpls_2025_1495779 crossref_primary_10_3390_molecules27154794 crossref_primary_10_3390_molecules24142533 crossref_primary_10_1021_acssynbio_4c00239 crossref_primary_10_3390_horticulturae10111165 crossref_primary_10_3390_molecules27092781 crossref_primary_10_3390_ph13110328 crossref_primary_10_3390_ijms23147929 crossref_primary_10_3390_molecules27175506 crossref_primary_10_3390_molecules27175503 crossref_primary_10_3390_molecules26216723 crossref_primary_10_1016_j_chroma_2021_462608 crossref_primary_10_1016_j_gtc_2021_03_009 crossref_primary_10_1007_s11926_022_01077_3 crossref_primary_10_1016_j_rvsc_2024_105483 crossref_primary_10_1016_j_indcrop_2023_117143 crossref_primary_10_3390_nano11092227 crossref_primary_10_1016_j_microc_2025_113062 crossref_primary_10_1016_j_jep_2022_115312 crossref_primary_10_3390_plants12213756 crossref_primary_10_1016_j_lwt_2024_115807 crossref_primary_10_1016_j_jep_2024_118141 crossref_primary_10_38001_ijlsb_1198033 crossref_primary_10_1038_s42003_025_07509_x crossref_primary_10_1186_s42238_021_00063_3 crossref_primary_10_2174_1381612826666201202125807 crossref_primary_10_1016_j_clinthera_2023_04_011 crossref_primary_10_1186_s13643_024_02657_3 crossref_primary_10_3390_ijms222111989 crossref_primary_10_1021_acs_jnatprod_3c00831 crossref_primary_10_3390_nu17010059 crossref_primary_10_1097_FTD_0000000000000667 crossref_primary_10_1016_j_nbd_2023_106235 crossref_primary_10_1080_14786419_2020_1781111 crossref_primary_10_2174_0929867327666200210144847 crossref_primary_10_3389_fphar_2023_1053680 crossref_primary_10_2174_1386207326666230210141218 crossref_primary_10_3390_plants11131749 crossref_primary_10_1016_j_jpba_2021_114346 crossref_primary_10_1111_ajco_14149 crossref_primary_10_3390_biomedicines10081820 crossref_primary_10_47836_mjmhs_19_s9_43 crossref_primary_10_1089_can_2022_0305 crossref_primary_10_3390_biom11040582 crossref_primary_10_1016_j_indcrop_2019_112042 crossref_primary_10_1016_j_jep_2021_114362 crossref_primary_10_1016_j_bcp_2024_116082 crossref_primary_10_2174_2666779701666210408111006 crossref_primary_10_3390_plants12213731 crossref_primary_10_1039_C9AN00890J crossref_primary_10_1016_j_colsurfb_2022_113020 crossref_primary_10_1016_j_heliyon_2023_e16913 crossref_primary_10_1016_j_fsisyn_2020_01_019 crossref_primary_10_1177_1074248420935743 crossref_primary_10_3390_tropicalmed7120400 crossref_primary_10_1038_s41598_024_66420_3 crossref_primary_10_1016_j_jpba_2021_114125 crossref_primary_10_1016_j_indcrop_2020_112238 crossref_primary_10_1016_j_chroma_2024_465225 crossref_primary_10_1016_j_focha_2024_100719 crossref_primary_10_3390_horticulturae10101060 crossref_primary_10_3390_fermentation7010006 crossref_primary_10_1016_j_jep_2020_113565 crossref_primary_10_1080_10643389_2020_1819730 crossref_primary_10_29058_mjwbs_928899 crossref_primary_10_1002_ptr_7213 crossref_primary_10_1016_j_lfs_2019_03_053 crossref_primary_10_3390_ijms20071673 crossref_primary_10_1007_s43450_023_00360_3 crossref_primary_10_3390_metabo13030442 crossref_primary_10_3390_molecules28083552 crossref_primary_10_1016_j_pestbp_2022_105117 crossref_primary_10_3390_app11209414 crossref_primary_10_2147_ITT_S267905 crossref_primary_10_3390_foods10050916 crossref_primary_10_3390_plants11131671 crossref_primary_10_1089_can_2023_0113 crossref_primary_10_3389_fphar_2021_736511 crossref_primary_10_3389_fphar_2022_923063 crossref_primary_10_3390_life10060086 crossref_primary_10_3390_foods13162584 crossref_primary_10_3390_ijms20235905 crossref_primary_10_3390_ijms20174308 crossref_primary_10_1002_mar_21730 crossref_primary_10_2174_0115734129347983241023100539 crossref_primary_10_3390_ijms24065251 crossref_primary_10_1097_CNQ_0000000000000303 crossref_primary_10_1007_s13596_021_00607_1 crossref_primary_10_3390_antiox11040660 crossref_primary_10_32345_2664_4738_2_2023_17 crossref_primary_10_1016_j_toxrep_2024_101685 crossref_primary_10_3390_agronomy15030564 crossref_primary_10_1097_CU9_0000000000000023 crossref_primary_10_1007_s10493_020_00540_z crossref_primary_10_3390_ijerph20095663 crossref_primary_10_22159_ajpcr_2023_v16i3_47462 crossref_primary_10_1016_j_maturitas_2018_10_010 crossref_primary_10_3390_foods10010029 crossref_primary_10_3389_fphar_2020_592981 crossref_primary_10_1007_s13258_023_01466_7 crossref_primary_10_1016_j_chroma_2020_461864 crossref_primary_10_3390_molecules25051091 crossref_primary_10_3390_molecules25163710 crossref_primary_10_1111_plb_13149 crossref_primary_10_3390_life12050682 crossref_primary_10_1016_j_compag_2023_108551 crossref_primary_10_19053_01217488_v15_n1_2024_15214 crossref_primary_10_47485_2767_5416_1039 crossref_primary_10_1002_fsn3_1976 crossref_primary_10_2174_1389201021666191210114127 crossref_primary_10_1002_jcph_2400 crossref_primary_10_3390_biomedicines10123142 crossref_primary_10_1089_can_2023_0200 crossref_primary_10_4049_jimmunol_2000213 crossref_primary_10_1107_S2052252525001009 crossref_primary_10_1016_j_scienta_2024_113299 crossref_primary_10_31887_DCNS_2020_22_3_mcrocq crossref_primary_10_1002_epi4_13081 crossref_primary_10_3390_app10238519 crossref_primary_10_1080_15440478_2021_1904482 crossref_primary_10_20935_AcadBiol7344 crossref_primary_10_3390_biom9110732 crossref_primary_10_1016_j_pnpbp_2020_109873 crossref_primary_10_3390_analytica5010006 crossref_primary_10_1016_j_indcrop_2020_112726 crossref_primary_10_1186_s10020_024_01013_4 crossref_primary_10_1016_j_jep_2025_119486 crossref_primary_10_1186_s42238_021_00105_w crossref_primary_10_3389_fphar_2023_1200269 crossref_primary_10_3390_molecules27020491 crossref_primary_10_31083_j_fbe1401001 crossref_primary_10_1007_s00011_023_01831_y crossref_primary_10_1080_10942912_2020_1797783 crossref_primary_10_3390_nu15204350 crossref_primary_10_1016_j_polgeo_2022_102781 crossref_primary_10_1177_2150132720946954 crossref_primary_10_1007_s10571_022_01263_y crossref_primary_10_3390_molecules25204682 crossref_primary_10_3390_cosmetics11010022 crossref_primary_10_3390_molecules27185856 crossref_primary_10_3390_molecules24122329 crossref_primary_10_1111_1541_4337_12730 crossref_primary_10_3389_fphys_2021_785176 crossref_primary_10_3390_ph14121224 crossref_primary_10_3390_molecules24193602 crossref_primary_10_1007_s00216_023_04782_9 crossref_primary_10_3389_fpls_2024_1381154 crossref_primary_10_1007_s10311_020_01029_2 crossref_primary_10_1002_ffj_3732 crossref_primary_10_1007_s00580_022_03374_w crossref_primary_10_3390_foods12224066 crossref_primary_10_3390_biomedicines13030530 crossref_primary_10_3390_molecules26061588 crossref_primary_10_3390_molecules27185746 crossref_primary_10_1016_j_fitote_2023_105467 crossref_primary_10_3390_ijms25084204 crossref_primary_10_1016_j_ejmech_2024_116164 crossref_primary_10_1128_MRA_00653_23 crossref_primary_10_3390_molecules28207005 crossref_primary_10_1016_j_neubiorev_2019_10_014 crossref_primary_10_3390_biology10060542 crossref_primary_10_1002_prp2_761 crossref_primary_10_3390_molecules26134080 crossref_primary_10_3390_agronomy13122865 crossref_primary_10_1177_1942602X19877561 crossref_primary_10_1016_j_lfs_2023_121838 crossref_primary_10_1186_s42238_023_00172_1 crossref_primary_10_3233_JAD_201045 crossref_primary_10_2174_1570159X18666200720172624 crossref_primary_10_3390_ijms20184512 crossref_primary_10_1177_2324709620947267 crossref_primary_10_1097_FBP_0000000000000627 crossref_primary_10_1590_s2175_97902022e20161 crossref_primary_10_17221_223_2022_PSE crossref_primary_10_1016_j_surfin_2024_104865 crossref_primary_10_3389_fpls_2021_753847 crossref_primary_10_1016_j_rvsc_2021_12_012 crossref_primary_10_3390_stresses5010007 crossref_primary_10_3390_molecules27051689 crossref_primary_10_3390_molecules28062791 crossref_primary_10_1007_s10123_024_00505_x crossref_primary_10_1055_a_1420_5780 crossref_primary_10_3390_cancers14040885 crossref_primary_10_3389_fpls_2024_1279738 crossref_primary_10_1007_s10389_021_01624_9 crossref_primary_10_1016_j_cdnut_2023_101972 crossref_primary_10_3390_medicines6010031 crossref_primary_10_1208_s12249_024_02836_4 crossref_primary_10_3390_agriculture14060940 crossref_primary_10_1016_j_pbb_2020_172982 crossref_primary_10_2174_1872210513666190308133429 crossref_primary_10_1016_j_rser_2021_110784 crossref_primary_10_1016_j_sajb_2023_08_008 crossref_primary_10_1146_annurev_food_032519_051834 crossref_primary_10_3390_plants11151900 crossref_primary_10_1016_j_jep_2020_113743 crossref_primary_10_3390_separations7020020 crossref_primary_10_55530_ijmbiosnepal_v5i2_37 crossref_primary_10_3390_ddc3010011 crossref_primary_10_1002_cbf_4100 crossref_primary_10_1002_jib_654 crossref_primary_10_3390_foods9081118 crossref_primary_10_1139_cjb_2021_0178 crossref_primary_10_3390_cancers16162909 crossref_primary_10_1016_j_foodchem_2020_126469 crossref_primary_10_3390_foods9081123 crossref_primary_10_3390_molecules24122256 crossref_primary_10_3390_ph18020202 crossref_primary_10_3390_app14052177 crossref_primary_10_3390_pharmaceutics11010033 crossref_primary_10_1007_s43630_024_00589_4 crossref_primary_10_2139_ssrn_4972616 crossref_primary_10_3390_plants12030510 crossref_primary_10_1111_bcp_14140 crossref_primary_10_15429_jkomor_2023_23_2_51 crossref_primary_10_3390_molecules26134041 crossref_primary_10_3389_fphar_2021_705402 crossref_primary_10_3390_molecules26113343 crossref_primary_10_3390_molecules23123149 crossref_primary_10_61186_phypha_27_2_100 crossref_primary_10_1021_acs_jafc_1c08235 crossref_primary_10_1007_s12098_024_05337_1 crossref_primary_10_1080_15440478_2021_1889443 crossref_primary_10_1186_s12906_019_2541_5 crossref_primary_10_3389_fncel_2022_917164 crossref_primary_10_3390_molecules29020410 crossref_primary_10_1038_s41429_024_00793_5 crossref_primary_10_3390_ijms24021329 crossref_primary_10_3389_fmicb_2021_714993 crossref_primary_10_3390_metabo12060480 crossref_primary_10_3390_su15129610 crossref_primary_10_1186_s12906_020_03046_8 crossref_primary_10_3390_molecules27041448 crossref_primary_10_3389_fpls_2021_657323 crossref_primary_10_1007_s00580_022_03339_z crossref_primary_10_1186_s42238_022_00142_z crossref_primary_10_32712_2446_4775_2022_1306 crossref_primary_10_32604_phyton_2022_021288 crossref_primary_10_3390_toxins13020117 crossref_primary_10_52326_jss_utm_2024_7_1__02 crossref_primary_10_1093_hr_uhad150 crossref_primary_10_1093_hr_uhae245 crossref_primary_10_1177_0022042620911367 crossref_primary_10_1016_j_jpba_2020_113633 crossref_primary_10_3390_biomedicines10040796 crossref_primary_10_3390_molecules26030570 crossref_primary_10_52711_0974_360X_2023_00361 crossref_primary_10_3390_medicines6010003 crossref_primary_10_1111_1750_3841_15614 crossref_primary_10_1016_j_jas_2023_105873 crossref_primary_10_61186_JCT_14_4_337 crossref_primary_10_1590_0004_282x_anp_2020_0432 crossref_primary_10_1038_s41477_021_01003_y crossref_primary_10_1089_can_2022_0096 crossref_primary_10_3390_ph15020210 crossref_primary_10_1016_j_indcrop_2025_120566 crossref_primary_10_3390_molecules28073271 crossref_primary_10_1007_s40429_025_00619_w crossref_primary_10_1186_s42238_020_00028_y crossref_primary_10_3390_proteomes8020013 crossref_primary_10_3390_biom10050803 crossref_primary_10_1016_j_fbio_2024_105344 crossref_primary_10_1016_j_smrv_2020_101339 crossref_primary_10_56083_RCV4N1_046 crossref_primary_10_3389_fvets_2021_645667 crossref_primary_10_1016_j_ces_2023_119279 crossref_primary_10_1080_14786419_2020_1869230 crossref_primary_10_1016_j_fsigen_2024_103123 crossref_primary_10_1016_j_toxlet_2024_08_012 crossref_primary_10_1002_agj2_70006 crossref_primary_10_1016_j_bone_2024_117035 crossref_primary_10_1016_j_phytol_2022_08_004 crossref_primary_10_1155_2020_6056373 |
| Cites_doi | 10.1089/can.2017.0027 10.3390/molecules191118781 10.1124/pr.115.011478 10.1089/rej.2013.1515 10.5962/p.168641 10.1016/j.tips.2009.07.006 10.1007/BF02863315 10.3322/canjclin.52.2.72 10.1007/s10722-003-4452-y 10.1001/jama.2015.6358 10.1016/bs.apha.2017.05.003 10.1016/j.jep.2014.04.052 10.1016/j.jep.2006.05.034 10.1016/0376-8716(82)90036-9 10.1111/bph.12120 10.1111/j.1467-9566.2012.01476.x 10.3390/agronomy6040058 10.1002/med.20135 10.1176/appi.neuropsych.16110310 10.1111/bph.13892 10.1016/j.indcrop.2016.04.026 10.2146/ajhp140523 10.1016/0378-8741(84)90036-9 10.1007/s00482-015-0092-3 10.3389/fneur.2017.00299 10.1016/j.ejfs.2014.07.008 10.3233/JAD-2012-111862 10.1016/j.pharmthera.2011.09.002 10.1093/jxb/ern260 10.1016/j.bcp.2010.02.015 10.1007/s00213-017-4766-7 10.1186/1746-4269-6-1 10.1080/02791072.1981.10471447 10.1093/ibd/izy014 10.1016/j.brainresrev.2003.11.005 10.1159/000358155 10.1007/s11910-018-0814-x 10.1016/j.yebeh.2018.07.020 10.1016/j.euroneuro.2017.03.010 10.1186/1746-4269-9-84 10.1021/ja01092a065 10.1016/j.jaa.2009.02.003 10.1017/S0003598X0008368X 10.1021/ml200313p 10.1080/17474124.2017.1292851 10.1007/s11746-006-1207-x 10.1093/cercor/bhw037 10.1038/bjp.2008.190 10.1517/13543784.2014.918603 10.1136/bmj.332.7534.175 10.1111/j.1476-5381.2011.01238.x 10.1186/1746-4269-9-25 10.1016/S0379-0738(02)00397-3 10.1007/s003340200039 10.1186/1746-4269-6-4 10.1002/eat.22173 10.1093/sleep/zsx112 10.1007/BF02862859 10.1016/j.bbr.2012.06.033 10.1038/372686a0 10.1663/0013-0001(2003)057[0295:AEFTTO]2.0.CO;2 10.1039/C6NP00074F 10.1023/A:1007178924408 10.1001/archgenpsychiatry.2008.519 10.1016/j.fitote.2018.02.002 10.5664/jcsm.7070 10.1016/j.jebo.2018.02.005 10.1515/hmbci-2018-0013 10.1016/j.phytochem.2012.11.001 10.1186/1746-4269-6-35 10.1186/1746-4269-10-9 10.1038/s41401-018-0031-9 10.1300/J175v02n02_04 10.1007/s00213-014-3749-1 10.1124/jpet.107.134809 10.1186/1746-4269-8-39 10.1016/j.phrs.2016.07.045 10.1212/WNL.0000000000000446 10.1002/cam4.816 10.3390/ph11020055 10.1007/s40265-017-0720-6 10.1016/j.ejphar.2014.02.013 10.1002/ptr.5975 10.1038/nm.4311 10.1007/s11910-018-0859-x 10.1016/0278-6915(83)90161-8 10.1155/2016/5962832 10.1016/j.bbr.2010.11.022 10.1016/j.phrs.2013.12.010 10.1002/cbdv.200790145 10.3892/or.2012.2093 10.1002/hup.1048 10.1073/pnas.1200662109 10.1007/BF00973103 10.1021/np500292g 10.9758/cpn.2017.15.4.301 10.3389/fphar.2016.00341 10.1007/s40273-017-0565-6 10.1097/FBP.0000000000000285 10.1142/S0192415X15500457 10.1002/cne.1078 10.1080/13880209.2016.1228682 10.1016/j.phymed.2013.12.004 10.3389/fphar.2018.00733 10.1016/j.neuint.2013.08.002 10.1016/S0014-2999(98)00649-9 10.1212/01.WNL.0000091868.28557.B8 10.1111/j.1476-5381.2009.00515.x 10.1016/j.toxrep.2015.05.003 10.1212/WNL.90.15_supplement.P3.318 10.1038/npjamd.2016.12 10.1007/s12229-015-9157-3 10.1016/j.ejphar.2013.09.068 10.1016/j.jep.2011.01.042 10.1111/ane.12202 10.1111/j.1360-0443.2008.02169.x 10.1177/0959683616650268 10.5962/p.168565 10.1111/ane.12712 10.1038/sj.bjp.0707442 10.1212/WNL.0000000000000363 10.1093/carcin/bgu205 10.1111/bph.14382 10.1007/s00213-006-0343-1 10.1016/j.biopsych.2011.05.010 10.1002/dta.1425 10.1525/ac.2006.17.2.78 10.3233/JAD-130137 10.1007/s11920-017-0775-9 10.1007/BF02976937 10.1089/can.2017.0028 10.1523/JNEUROSCI.16-24-08057.1996 10.1007/s00280-017-3387-5 10.1046/j.1432-1327.2000.01550.x 10.1371/journal.pone.0129618 10.3390/molecules22081369 10.1016/S0306-4522(97)00436-3 10.1016/j.neuropharm.2018.07.002 10.1136/bmj.325.7374.1195 10.1016/j.jagp.2012.11.022 10.1073/pnas.96.10.5780 10.1186/1746-4269-9-9 10.1016/j.neuro.2011.12.015 10.1016/j.ypmed.2017.01.024 10.1016/j.pbb.2011.08.029 10.1186/1746-4269-10-26 10.1186/s13002-016-0110-2 10.1007/s13311-015-0377-3 10.1007/BF02244601 10.3389/fpls.2016.00019 10.1104/pp.17.00727 10.1371/journal.pone.0173911 10.2337/db09-1482 10.1523/JNEUROSCI.0943-13.2013 10.1038/sj.bjp.0706406 10.1021/np8002673 10.1016/j.euroneuro.2013.10.008 10.1016/j.ejmech.2012.12.056 10.1007/s12640-017-9806-x 10.20882/adicciones.858 10.2174/1874473710801010081 10.3389/fnins.2017.00293 10.1186/1746-4269-7-31 10.1002/cbdv.200790144 10.1016/j.phrs.2013.06.001 10.1007/978-1-59259-947-9_2 10.3390/ijms18081739 10.1007/s10722-013-0001-5 10.1111/j.1476-5381.2010.00756.x 10.2174/187152412803760636 10.2307/1220524 |
| ContentType | Journal Article |
| Copyright | 2018 Elsevier B.V. Copyright © 2018 Elsevier B.V. All rights reserved. |
| Copyright_xml | – notice: 2018 Elsevier B.V. – notice: Copyright © 2018 Elsevier B.V. All rights reserved. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 ADTPV AOWAS |
| DOI | 10.1016/j.jep.2018.09.004 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic AGRICOLA AGRICOLA - Academic SwePub SwePub Articles |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | MEDLINE AGRICOLA MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Pharmacy, Therapeutics, & Pharmacology |
| EISSN | 1872-7573 |
| EndPage | 315 |
| ExternalDocumentID | oai_swepub_ki_se_485675 30205181 10_1016_j_jep_2018_09_004 S0378874118316611 |
| Genre | Historical Article Journal Article Review |
| GeographicLocations | Asia |
| GeographicLocations_xml | – name: Asia |
| GroupedDBID | --- --K --M .~1 0R~ 1B1 1RT 1~. 1~5 4.4 457 4G. 5GY 7-5 71M 8P~ 9JM AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AATCM AAWTL AAXUO ABFNM ABFRF ABJNI ABMAC ABYKQ ABZDS ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE AEBSH AEFWE AEKER AENEX AFKWA AFTJW AFXIZ AGUBO AGYEJ AIEXJ AIKHN AITUG AJOXV ALCLG ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AXJTR BKOJK BLXMC CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FIRID FNPLU FYGXN G-Q GBLVA IHE J1W KOM M34 M41 MO0 N9A O-L O9- OAUVE OGGZJ OZT P-8 P-9 P2P PC. Q38 RIG ROL RPZ SCC SDF SDG SDP SES SPCBC SPT SSP SSZ T5K TN5 ~G- ~KM .GJ 29K 53G 5VS AAHBH AAQFI AAQXK AATTM AAXKI AAYWO AAYXX ABWVN ABXDB ACRPL ACVFH ADCNI ADMUD ADNMO ADVLN AEIPS AEUPX AFJKZ AFPUW AGCQF AGHFR AGQPQ AGRNS AHHHB AIGII AIIUN AKBMS AKRWK AKYEP ANKPU APXCP ASPBG AVWKF AZFZN BNPGV CITATION D-I FEDTE FGOYB G-2 HMT HVGLF HX~ HZ~ R2- SEW SSH WUQ ZGI CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 ADTPV AOWAS EFKBS |
| ID | FETCH-LOGICAL-c424t-a2e8207c708108f217a4154e4658a8c37fee65bbe48c0e4e9536e717444ec8733 |
| IEDL.DBID | .~1 |
| ISSN | 0378-8741 1872-7573 |
| IngestDate | Mon Aug 25 03:34:05 EDT 2025 Fri Jul 11 09:48:09 EDT 2025 Thu Jul 10 18:40:26 EDT 2025 Thu Apr 03 07:02:12 EDT 2025 Tue Jul 01 01:35:42 EDT 2025 Thu Apr 24 22:54:23 EDT 2025 Fri Feb 23 02:28:30 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | Phytocannabinoids Cannabis sativa L Ethnobotany Terpenoids Endocannabinoids |
| Language | English |
| License | Copyright © 2018 Elsevier B.V. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c424t-a2e8207c708108f217a4154e4658a8c37fee65bbe48c0e4e9536e717444ec8733 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| PMID | 30205181 |
| PQID | 2102920950 |
| PQPubID | 23479 |
| PageCount | 16 |
| ParticipantIDs | swepub_primary_oai_swepub_ki_se_485675 proquest_miscellaneous_2153617693 proquest_miscellaneous_2102920950 pubmed_primary_30205181 crossref_citationtrail_10_1016_j_jep_2018_09_004 crossref_primary_10_1016_j_jep_2018_09_004 elsevier_sciencedirect_doi_10_1016_j_jep_2018_09_004 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2018-12-05 |
| PublicationDateYYYYMMDD | 2018-12-05 |
| PublicationDate_xml | – month: 12 year: 2018 text: 2018-12-05 day: 05 |
| PublicationDecade | 2010 |
| PublicationPlace | Ireland |
| PublicationPlace_xml | – name: Ireland |
| PublicationTitle | Journal of ethnopharmacology |
| PublicationTitleAlternate | J Ethnopharmacol |
| PublicationYear | 2018 |
| Publisher | Elsevier B.V |
| Publisher_xml | – name: Elsevier B.V |
| References | Kors, Peters (bib101) 2000 Jauregui, Clavo, Jovel, Pardo-de-Santayana (bib91) 2011; 134 Fleischhauer (bib65) 1956; 9 Happyana, Agnolet, Muntendam, Van Dam, Schneider, Kayser (bib78) 2013; 87 Taura, Sirikantaramas, Shoyama, Shoyama, Morimoto (bib190) 2007; 4 Kunwar, Shrestha, Bussmann (bib103) 2010; 6 Badowski (bib21) 2017; 80 Koch (bib99) 2017; 11 Wilkins, S.J., 1999. Method for Treating Gastrointestinal Disorders. Patent Number: US6420435B1. Mastinu, Premoli, Ferrari-Toninelli, Tambaro, Maccarinelli, Memo, Bonini (bib119) 2018 Shinjyo, Di Marzo (bib173) 2013; 63 Giacoppo, Mandolino, Galuppo, Bramanti, Mazzon (bib72) 2014; 19 Tafelski, Häuser, Schäfer (bib187) 2016; 30 Hall (bib75) 2008; 103 Laun, Shrader, Brown, Song (bib105) 2018 Russo (bib159) 2007; 4 Herzog, Shanahan, Grimison, Tran, Wong, Lintzeris, Simes, Stockler, Morton (bib81) 2018; 36 McGinty, Niederdeppe, Heley, Barry (bib120) 2017; 99 Pagano, Montanaro, Di Girolamo, Pistone, Altieri, Zjawiony, Izzo, Capasso (bib141) 2015; 10 Savonenko, Melnikova, Wang, Ravert, Gao, Koppel, Lee, Pletnikova, Cho, Sayyida, Hiatt, Troncoso, Davies, Dannals, Pomper, Horti (bib166) 2015; 10 Bonnie, Whitebread (bib31) 1974 . Harvey, Ohlsson, Mååg, Musgrave, Smid (bib79) 2012; 33 Cherney, Small (bib44) 2016; 6 Jakubovski, Müller-Vahl (bib90) 2017; 18 Hasenoehrl, Storr, Schicho (bib80) 2017; 11 Calik, Carley (bib39) 2017; 40 Schussel, Kenzo, Santos, Bueno, Yoshimura, de Oliveira Cruz Latorraca, Pachito, Riera (bib171) 2018; 32 Clarke, Merlin (bib45) 2013 Brenneisen (bib35) 2007 Kowal, Hazekamp, Colzato, van Steenbergen, van der Wee, Durieux, Manai, Hommel (bib102) 2015; 232 Levinthal (bib111) 2012 Opdyke (bib138) 1983; 21 Bussmann, Paniagua Zambrana, Sikharulidze, Kikvidze, Kikodze, Tchelidze, Khutsishvili, Batsatsashvili, Hart (bib37) 2016; 12 Scherma, Satta, Collu, Boi, Usai, Fratta, Fadda (bib168) 2017; 174 Gérard, Pieters, Goffin, Bormans, Van Laere (bib71) 2011; 70 Ryz, Remillard, Russo (bib162) 2017; 2 Abel (bib2) 1980 Mechoulam, Gaoni (bib125) 1965; 87 Farag, Kayser (bib61) 2017 Nicolussi, Viveros-Paredes, Gachet, Rau, Flores-Soto, Blunder, Gertsch (bib136) 2014; 80 Sauer (bib164) 1952 Schenberg (bib167) 2018; 9 Brierley, Samuels, Duncan, Whalley, Williams (bib36) 2017; 28 Szaflarski, Bebin, Cutter, DeWolfe, Dure, Gaston, Kankirawatana, Liu, Singh, Standaert, Thomas, Ver Hoef, UAB CBD Program (bib186) 2018 Brecher, E.M., Editors of Consumer Reports Magazine, 1972. The Consumers Union Report on Licit and Illicit Drugs. Schaffer Library of Drug Policy. (ISBN 0316153400). Aso, Juvés, Maldonado, Ferrer (bib19) 2013; 35 Hill, Williams, Whalley, Stephens (bib82) 2012; 133 Gagliano (bib69) 2013; 5 Hanus (bib76) 2009; 29 Piluzza, Delogu, Cabras, Marceddu, Bullitta (bib150) 2013; 60 Souto-Maior, Fonsêca, Salgado, Monte, de Sousa, de Almeida (bib182) 2017; 55 Ramar, Rosen, Kirsch, Chervin, Carden, Aurora, Kristo, Malhotra, Martin, Olson, Rosen, Rowley (bib152) 2018; 14 Namsa, Mandal, Tangjang, Mandal (bib134) 2011; 7 VanPool (bib196) 2009; 28 Akhtar, Rashid, Murad, Bergmeier (bib6) 2013; 9 O'Shaughnessy (bib139) 1843; 5 Fernández-Ruiz (bib62) 2018 Rudroff, Honce (bib158) 2017; 8 Owokotomo, Ekundayo, Abayomi, Chukwuka (bib140) 2015; 2 Armijos, Cota, González (bib16) 2014; 10 Nielsen, Germanos, Weier, Pollard, Degenhardt, Hall, Buckley, Farrell (bib137) 2018; 18 Chait (bib43) 1990; 100 Tsuchiya (bib195) 2017; 22 Nichols (bib135) 2016; 68 Luna (bib114) 1984; 11 Babson, Sottile, Morabito (bib20) 2017; 19 Flachenecker, Henze, Zettl (bib64) 2014; 129 Tayyab, Shahwar (bib191) 2015; 5 Yang, Michel, Chaumont, Millet-Clerc (bib202) 1999; 148 Nabukenya, Rubaire-Akiiki, Olila, Ikwap, Höglund (bib131) 2014; 10 Walther, Mahlberg, Eichmann, Kunz (bib197) 2006; 185 De Petrocellis, Vellani, Schiano-Moriello, Marini, Magherini, Orlando, Di Marzo (bib53) 2008; 325 Thompson, Patterson, Hodges (bib192) 2003; 61 McPartland (bib123) 1997; 4 Suliman, Taib, Moklas, Basir (bib185) 2018; 33 Andre, Hausman, Guerriero (bib11) 2016; 7 Zimmer, Zimmer, Hohmann, Herkenham, Bonner (bib204) 1999; 96 Pedersen, Sandberg (bib147) 2013; 35 Leonti, Casu, Raduner, Cottiglia, Floris, Altmann, Gertsch (bib110) 2010; 79 Moreau (bib129) 1973 Soelberg Sorensen (bib179) 2017; 136 Hajdu, Nicolussi, Rau, Lorántfy, Forgo, Hohmann, Csupor, Gertsch (bib74) 2014; 77 Latta, Eaton (bib104) 1975; 29 Horn, Böhme, Dietrich, Koch (bib84) 2018; 11 Solowij, Battisti (bib180) 2008; 1 Betthauser, Pilz, Vollmer (bib27) 2015; 72 Aran, Cassuto, Lubotzky (bib15) 2018; 90 Crippa, Zuardi, Martín-Santos, Bhattacharyya, Atakan, McGuire, Fusar-Poli (bib48) 2009; 24 de Cássia da Silveira, Lima, da Nóbrega, de Brito, de Sousa (bib52) 2017; 9 Huchelmann, Boutry, Hachez (bib85) 2017; 175 McPartland (bib124) 2004; 45 Akerman, Holland, Lasalandra, Goadsby (bib5) 2013; 33 Aso, Palomer, Juvés, Maldonado, Muñoz, Ferrer (bib18) 2012; 30 Borrelli, Pagano, Romano, Panzera, Maiello, Coppola, De Petrocellis, Buono, Orlando, Izzo (bib33) 2014; 12 Lazzari, Pau, Tambaro, Asproni, Ruiu, Pinna, Mastinu, Curzu, Reali, Bottazzi, Pinna, Murineddu (bib107) 2012; 12 Anwara, F., Latifa, S., Ashrafb, M., 2006. Analytical Characterization of Hemp (Cannabis sativa) Seed Oil from Different Agro-Ecological Zones of Pakistan, 83, pp. 323–329. Bai, Zheng, Wang, Liu (bib22) 2016; 2016 Manca, Mastinu, Olimpieri, Falzoi, Sani, Ruiu, Loriga, Volonterio, Tambaro, Bottazzi, Zanda, Pinna, Lazzari (bib116) 2013; 62 Romano, Borrelli, Fasolino, Capasso, Piscitelli, Cascio, Pertwee, Coppola, Vassallo, Orlando, Di Marzo, Izzo (bib156) 2013; 169 Allan, Finley, Ton, Perry, Ramji, Crawford, Lindblad, Korownyk, Kolber (bib8) 2018; 64 d'Alessio, Bisson, Béné (bib50) 2014; 17 Schultes, Klein, Plowman, Lockwood (bib169) 1974; 23 Smeriglio, Giofrè, Galati, Monforte, Cicero, D'Angelo, Grassi, Circosta (bib178) 2018; 127 Koppel, Brust, Fife, Bronstein, Youssof, Gronseth, Gloss (bib100) 2014; 82 Abi-Jaoude, Chen, Cheung, Bhikram, Sandor (bib3) 2017; 29 Savo, La Rocca, Caneva, Rapallo, Cornara (bib165) 2013; 9 Russo (bib160) 2011; 163 Booth, Page, Bohlmann (bib32) 2017; 12 Pagano, Capasso, Piscitelli, Romano, Parisi, Finizio, Lauritano, Di Marzo, Izzo, Borrelli (bib142) 2016; 7 Adovasio, Soffer, Klima (bib4) 1996; 70 Casajuana Köguel, López-Pelayo, Balcells-Olivero, Colom, Gual (bib41) 2018; 30 Dennis, Whalley, Stephens (bib55) 2008; 154 Jeong, Cho, Shin, Jeon, Kim, Lee, Kim, Lee (bib92) 2014; 154 Deiana (bib54) 2013; 5 Rampa, Bartolini, Bisi, Belluti, Gobbi, Andrisano, Ligresti, Di Marzo (bib153) 2012; 3 Tang, Struik, Yin, Thouminot, Bjelková, Stramkale, Amaducci (bib189) 2016; 87 Aso, Ferrer (bib17) 2016; 31 Cascio, Gauson, Stevenson, Ross, Pertwee (bib42) 2010; 159 Fachner (bib60) 2008; 17 Bilkei-Gorzo, Albayram, Draffehn, Michel, Piyanova, Oppenheimer, Dvir-Ginzberg, Rácz, Ulas, Imbeault, Bab, Schultze, Zimmer (bib28) 2017; 23 Starowicz, Finn (bib183) 2017; 80 Yun (bib203) 2014; 21 Barratt, Beaver, White (bib24) 1974; 8 Lee, M.A., 2013. Smoke Signals: A Social History of Marijuana: Medical, Recreational and Scientific. Scribner Paperback Edition. New York. (ISBN 1439102600). Anderson, Scurlock (bib9) 2005 Touwn (bib193) 1981; 13 Jia, Xi, Zhang, Chen, Lei, Dong, Yang (bib93) 2013; 29 Whiting, Wolff, Deshpande, Di Nisio, Duffy, Hernandez, Keurentjes, Lang, Misso, Ryder, Schmidlkofer, Westwood, Kleijnen (bib199) 2015; 313 Woodward, Harper, Stolyar, Forester, Ellison (bib201) 2014; 22 Jiang, Li, Zhao, Ferguson, Hueber, Bera, Wang, Zhao, Liu, Li (bib94) 2006; 108 Gakuubi, Wanzala (bib70) 2012; 8 Jourdan, Djaouti, Demizieux, Gresti, Vergès, Degrace (bib95) 2010; 59 Klauke, Racz, Pradier, Markert, Zimmer, Gertsch, Zimmer (bib98) 2014; 24 Keating (bib96) 2017; 77 Mechoulam, Fride, Di Marzo (bib126) 1998; 359 Fusar-Poli, Crippa, Bhattacharyya, Borgwardt, Allen, Martin-Santos, Seal, Surguladze, O'Carrol, Atakan, Zuardi, McGuire (bib68) 2009; 66 Hudson, Rushlow, Laviolette (bib86) 2018; 235 Inui (bib88) 2002; 52 McKenna (bib121) 1992 Bennett, C., 2011. Early/Ancient History, in Julie Holland (Eds), The Pot Book: A Complete Guide to Cannabis, Its Role in Medicine, Politics, Science, and Culture, Rochester, Vermont, pp. 17-26. Gilmore, Peakall, Robertson (bib73) 2003; 131 Panghal, Arya, Yadav, Kumar, Yadav (bib143) 2010; 6 Appendino, Gibbons, Giana, Pagani, Grassi, Stavri, Smith, Rahman (bib14) 2008; 71 Aldrich (bib7) 1997 Hanus, Meyer, Muñoz, Taglialatela-Scafati, Appendino (bib77) 2016; 33 Sim, Hampson, Deadwyler, Childers (bib174) 1996; 16 Di Marzo, Fontana, Cadas, Schinelli, Cimino, Schwartz, Piomelli (bib56) 1994; 372 McPartland, Di Marzo, De Petrocellis, Mercer, Glass (bib122) 2001; 436 Mercuri, Accorsi, Bandini Mazzanti (bib127) 2002; 11 Lazzari, Serra, Marcello, Pira, Mastinu (bib108) 2017; 27 Elisabetsky, Marschner, Souza (bib58) 1995; 20 Hillig (bib83) 2005; 52 Li (bib112) 1974; 28 Watts (bib198) 2006; 332 Merlin (bib128) 2003; 57 Tambaro, Casu, Mastinu, Lazzari (bib188) 2014; 729 Couch, Maudslay, Doleman, Lund, O'Sullivan (bib47) 2018; 24 Bonini, Mastinu, Maccarinelli, Mitola, Premoli, La Rosa, Ferrari-Toninelli, Grilli, Memo (bib30) 2016; 26 Butrica (bib38) 2002; 2 Pate (bib144) 1994; 2 Carod-Artal (bib40) 2013; 1 Currais, Quehenberger, Armando, Daugherty, Maher, Schubert (bib49) 2016; 23 Romano, Pagano, Orlando, Capasso, Cascio, Pertwee, Marzo, Izzo, Borrelli (bib157) 2016; 113(Pt A) Naftali, Mechulam, Lev, Konikoff (bib132) 2014; 32 Stevens, Murphy, Roberts, Lucas, Silva, Fuller (bib184) 2016; 26 Tsou, Brown, Sañudo-Peña, Mackie, Walker (bib194) 1998; 83 Lim, See, Lee (bib113) 2017; 15 Mastinu, Pira, Pinna, Pisu, Casu, Reali, Marcello, Murineddu, Lazzari (bib118) 2013; 74 Bang, Choi, Jang, Kim, Kwon, Kang, Won, Park, Baek (bib23) 2002; 25 Epstein (bib59) 2010; 8 Sirikantaramas, Taura (bib175) 2017 Freemon (bib67) 1982; 10 Izzo, Borrelli, Capasso, Di Marzo, Mechoulam (bib89) 2009; 30 Patton, Coffey, Carlin, Degenhardt, Lynskey, Hall (bib145) 2002; 325 Abbasi, Khan, Ahmad, Khan, Quave, Pieroni (bib1) 2013; 9 Benet (bib25) 1975 Pertwee (bib148) 2006; 147 Kim, Lee, Jeon, Han, Kee, Kim, Shin, Kang, Lee, Kim, Kim, Park, Choi, Park, Um, Hong (bib97) 2015; 43 Salzet, Breton, Biso Bonini (10.1016/j.jep.2018.09.004_bib30) 2016; 26 Brierley (10.1016/j.jep.2018.09.004_bib36) 2017; 28 Stevens (10.1016/j.jep.2018.09.004_bib184) 2016; 26 Zimmer (10.1016/j.jep.2018.09.004_bib204) 1999; 96 Calik (10.1016/j.jep.2018.09.004_bib39) 2017; 40 Aso (10.1016/j.jep.2018.09.004_bib19) 2013; 35 Aldrich (10.1016/j.jep.2018.09.004_bib7) 1997 Pavisian (10.1016/j.jep.2018.09.004_bib146) 2014; 82 Herzog (10.1016/j.jep.2018.09.004_bib81) 2018; 36 Ryz (10.1016/j.jep.2018.09.004_bib162) 2017; 2 Bolognini (10.1016/j.jep.2018.09.004_bib29) 2010; 160 Pate (10.1016/j.jep.2018.09.004_bib144) 1994; 2 Crippa (10.1016/j.jep.2018.09.004_bib48) 2009; 24 Tang (10.1016/j.jep.2018.09.004_bib189) 2016; 87 Riddle (10.1016/j.jep.2018.09.004_bib155) 2011 Russo (10.1016/j.jep.2018.09.004_bib161) 2008; 59 Schenberg (10.1016/j.jep.2018.09.004_bib167) 2018; 9 Merlin (10.1016/j.jep.2018.09.004_bib128) 2003; 57 Betthauser (10.1016/j.jep.2018.09.004_bib27) 2015; 72 Currais (10.1016/j.jep.2018.09.004_bib49) 2016; 23 Patton (10.1016/j.jep.2018.09.004_bib145) 2002; 325 Izzo (10.1016/j.jep.2018.09.004_bib89) 2009; 30 Jauregui (10.1016/j.jep.2018.09.004_bib91) 2011; 134 Solowij (10.1016/j.jep.2018.09.004_bib180) 2008; 1 Kunwar (10.1016/j.jep.2018.09.004_bib103) 2010; 6 Mastinu (10.1016/j.jep.2018.09.004_bib117) 2012; 234 McPartland (10.1016/j.jep.2018.09.004_bib124) 2004; 45 Hill (10.1016/j.jep.2018.09.004_bib82) 2012; 133 Jiang (10.1016/j.jep.2018.09.004_bib94) 2006; 108 Hanus (10.1016/j.jep.2018.09.004_bib77) 2016; 33 de Cássia da Silveira (10.1016/j.jep.2018.09.004_bib52) 2017; 9 Fernández-Ruiz (10.1016/j.jep.2018.09.004_bib62) 2018 Rice (10.1016/j.jep.2018.09.004_bib154) 2018; 18 Raman (10.1016/j.jep.2018.09.004_bib151) 1998 Suliman (10.1016/j.jep.2018.09.004_bib185) 2018; 33 Horn (10.1016/j.jep.2018.09.004_bib84) 2018; 11 Andries (10.1016/j.jep.2018.09.004_bib12) 2014; 47 Jakubovski (10.1016/j.jep.2018.09.004_bib90) 2017; 18 Lazzari (10.1016/j.jep.2018.09.004_bib108) 2017; 27 Sirikantaramas (10.1016/j.jep.2018.09.004_bib175) 2017 Aran (10.1016/j.jep.2018.09.004_bib15) 2018; 90 Klauke (10.1016/j.jep.2018.09.004_bib98) 2014; 24 Thompson (10.1016/j.jep.2018.09.004_bib192) 2003; 61 Touwn (10.1016/j.jep.2018.09.004_bib193) 1981; 13 Akerman (10.1016/j.jep.2018.09.004_bib5) 2013; 33 Gagliano (10.1016/j.jep.2018.09.004_bib69) 2013; 5 Walther (10.1016/j.jep.2018.09.004_bib197) 2006; 185 Bonnie (10.1016/j.jep.2018.09.004_bib31) 1974 Hall (10.1016/j.jep.2018.09.004_bib75) 2008; 103 Inui (10.1016/j.jep.2018.09.004_bib88) 2002; 52 Romano (10.1016/j.jep.2018.09.004_bib156) 2013; 169 Cherney (10.1016/j.jep.2018.09.004_bib44) 2016; 6 Badowski (10.1016/j.jep.2018.09.004_bib21) 2017; 80 McKenna (10.1016/j.jep.2018.09.004_bib121) 1992 Andre (10.1016/j.jep.2018.09.004_bib11) 2016; 7 Kim (10.1016/j.jep.2018.09.004_bib97) 2015; 43 Pertwee (10.1016/j.jep.2018.09.004_bib149) 2008; 153 Kowal (10.1016/j.jep.2018.09.004_bib102) 2015; 232 Jourdan (10.1016/j.jep.2018.09.004_bib95) 2010; 59 Keating (10.1016/j.jep.2018.09.004_bib96) 2017; 77 Hudson (10.1016/j.jep.2018.09.004_bib86) 2018; 235 Abbasi (10.1016/j.jep.2018.09.004_bib1) 2013; 9 Aso (10.1016/j.jep.2018.09.004_bib17) 2016; 31 Casajuana Köguel (10.1016/j.jep.2018.09.004_bib41) 2018; 30 Hajdu (10.1016/j.jep.2018.09.004_bib74) 2014; 77 Rudroff (10.1016/j.jep.2018.09.004_bib158) 2017; 8 Flachenecker (10.1016/j.jep.2018.09.004_bib64) 2014; 129 Li (10.1016/j.jep.2018.09.004_bib112) 1974; 28 Akhtar (10.1016/j.jep.2018.09.004_bib6) 2013; 9 Mulpuri (10.1016/j.jep.2018.09.004_bib130) 2018; 139 Nichols (10.1016/j.jep.2018.09.004_bib135) 2016; 68 Giacoppo (10.1016/j.jep.2018.09.004_bib72) 2014; 19 Souto-Maior (10.1016/j.jep.2018.09.004_bib182) 2017; 55 Bussmann (10.1016/j.jep.2018.09.004_bib37) 2016; 12 Dennis (10.1016/j.jep.2018.09.004_bib55) 2008; 154 Fusar-Poli (10.1016/j.jep.2018.09.004_bib68) 2009; 66 Starowicz (10.1016/j.jep.2018.09.004_bib183) 2017; 80 Romano (10.1016/j.jep.2018.09.004_bib157) 2016; 113(Pt A) De Petrocellis (10.1016/j.jep.2018.09.004_bib53) 2008; 325 d'Alessio (10.1016/j.jep.2018.09.004_bib50) 2014; 17 Luna (10.1016/j.jep.2018.09.004_bib114) 1984; 11 Tambaro (10.1016/j.jep.2018.09.004_bib188) 2014; 729 Mechoulam (10.1016/j.jep.2018.09.004_bib125) 1965; 87 Savonenko (10.1016/j.jep.2018.09.004_bib166) 2015; 10 Soelberg Sorensen (10.1016/j.jep.2018.09.004_bib179) 2017; 136 Epstein (10.1016/j.jep.2018.09.004_bib59) 2010; 8 Booth (10.1016/j.jep.2018.09.004_bib32) 2017; 12 Woodward (10.1016/j.jep.2018.09.004_bib201) 2014; 22 Nallathambi (10.1016/j.jep.2018.09.004_bib133) 2017; 2 Mastinu (10.1016/j.jep.2018.09.004_bib119) 2018 Moreau (10.1016/j.jep.2018.09.004_bib129) 1973 Couch (10.1016/j.jep.2018.09.004_bib47) 2018; 24 Laun (10.1016/j.jep.2018.09.004_bib105) 2018 Leonti (10.1016/j.jep.2018.09.004_bib110) 2010; 79 Taura (10.1016/j.jep.2018.09.004_bib190) 2007; 4 Cascio (10.1016/j.jep.2018.09.004_bib42) 2010; 159 Freemon (10.1016/j.jep.2018.09.004_bib67) 1982; 10 10.1016/j.jep.2018.09.004_bib13 Gilmore (10.1016/j.jep.2018.09.004_bib73) 2003; 131 Small (10.1016/j.jep.2018.09.004_bib176) 2015; 81 Bai (10.1016/j.jep.2018.09.004_bib22) 2016; 2016 10.1016/j.jep.2018.09.004_bib200 Souto-Maior (10.1016/j.jep.2018.09.004_bib181) 2011; 100 Butrica (10.1016/j.jep.2018.09.004_bib38) 2002; 2 Gérard (10.1016/j.jep.2018.09.004_bib71) 2011; 70 Mafimisebi (10.1016/j.jep.2018.09.004_bib115) 2010; 6 Lazzari (10.1016/j.jep.2018.09.004_bib107) 2012; 12 Yun (10.1016/j.jep.2018.09.004_bib203) 2014; 21 Koppel (10.1016/j.jep.2018.09.004_bib100) 2014; 82 Carod-Artal (10.1016/j.jep.2018.09.004_bib40) 2013; 1 Elisabetsky (10.1016/j.jep.2018.09.004_bib58) 1995; 20 Owokotomo (10.1016/j.jep.2018.09.004_bib140) 2015; 2 Pertwee (10.1016/j.jep.2018.09.004_bib148) 2006; 147 10.1016/j.jep.2018.09.004_bib26 Hasenoehrl (10.1016/j.jep.2018.09.004_bib80) 2017; 11 Tayyab (10.1016/j.jep.2018.09.004_bib191) 2015; 5 Hillig (10.1016/j.jep.2018.09.004_bib83) 2005; 52 Koch (10.1016/j.jep.2018.09.004_bib99) 2017; 11 Tafelski (10.1016/j.jep.2018.09.004_bib187) 2016; 30 Schultes (10.1016/j.jep.2018.09.004_bib169) 1974; 23 Lazzari (10.1016/j.jep.2018.09.004_bib106) 2011; 217 Farag (10.1016/j.jep.2018.09.004_bib61) 2017 Abel (10.1016/j.jep.2018.09.004_bib2) 1980 Tsuchiya (10.1016/j.jep.2018.09.004_bib195) 2017; 22 10.1016/j.jep.2018.09.004_bib109 10.1016/j.jep.2018.09.004_bib34 Schussel (10.1016/j.jep.2018.09.004_bib171) 2018; 32 Scherma (10.1016/j.jep.2018.09.004_bib168) 2017; 174 Schultes (10.1016/j.jep.2018.09.004_bib170) 1992 Bang (10.1016/j.jep.2018.09.004_bib23) 2002; 25 Kors (10.1016/j.jep.2018.09.004_bib101) 2000 VanPool (10.1016/j.jep.2018.09.004_bib196) 2009; 28 Nielsen (10.1016/j.jep.2018.09.004_bib137) 2018; 18 Harvey (10.1016/j.jep.2018.09.004_bib79) 2012; 33 Sharkey (10.1016/j.jep.2018.09.004_bib172) 2014; 722 Fidyt (10.1016/j.jep.2018.09.004_bib63) 2016; 5 Panghal (10.1016/j.jep.2018.09.004_bib143) 2010; 6 Tsou (10.1016/j.jep.2018.09.004_bib194) 1998; 83 Namsa (10.1016/j.jep.2018.09.004_bib134) 2011; 7 Happyana (10.1016/j.jep.2018.09.004_bib78) 2013; 87 Allan (10.1016/j.jep.2018.09.004_bib8) 2018; 64 Clarke (10.1016/j.jep.2018.09.004_bib46) 2016; 110 Levinthal (10.1016/j.jep.2018.09.004_bib111) 2012 Nicolussi (10.1016/j.jep.2018.09.004_bib136) 2014; 80 Naftali (10.1016/j.jep.2018.09.004_bib132) 2014; 32 Russo (10.1016/j.jep.2018.09.004_bib159) 2007; 4 Bilkei-Gorzo (10.1016/j.jep.2018.09.004_bib28) 2017; 23 Ibeas Bih (10.1016/j.jep.2018.09.004_bib87) 2015; 12 Anderson (10.1016/j.jep.2018.09.004_bib9) 2005 Davis (10.1016/j.jep.2018.09.004_bib51) 2014; 23 Szaflarski (10.1016/j.jep.2018.09.004_bib186) 2018 Mastinu (10.1016/j.jep.2018.09.004_bib118) 2013; 74 Deiana (10.1016/j.jep.2018.09.004_bib54) 2013; 5 Jia (10.1016/j.jep.2018.09.004_bib93) 2013; 29 Sauer (10.1016/j.jep.2018.09.004_bib164) 1952 Fleischhauer (10.1016/j.jep.2018.09.004_bib65) 1956; 9 Pagano (10.1016/j.jep.2018.09.004_bib141) 2015; 10 Piluzza (10.1016/j.jep.2018.09.004_bib150) 2013; 60 Clarke (10.1016/j.jep.2018.09.004_bib45) 2013 Anderson (10.1016/j.jep.2018.09.004_bib10) 1980; 28 Huchelmann (10.1016/j.jep.2018.09.004_bib85) 2017; 175 Sim (10.1016/j.jep.2018.09.004_bib174) 1996; 16 Mechoulam (10.1016/j.jep.2018.09.004_bib126) 1998; 359 Jeong (10.1016/j.jep.2018.09.004_bib92) 2014; 154 McPartland (10.1016/j.jep.2018.09.004_bib123) 1997; 4 Mercuri (10.1016/j.jep.2018.09.004_bib127) 2002; 11 Di Marzo (10.1016/j.jep.2018.09.004_bib56) 1994; 372 Shinjyo (10.1016/j.jep.2018.09.004_bib173) 2013; 63 McPartland (10.1016/j.jep.2018.09.004_bib122) 2001; 436 Nabukenya (10.1016/j.jep.2018.09.004_bib131) 2014; 10 Chait (10.1016/j.jep.2018.09.004_bib43) 1990; 100 Whiting (10.1016/j.jep.2018.09.004_bib199) 2015; 313 Fort (10.1016/j.jep.2018.09.004_bib66) 2012; 109 Latta (10.1016/j.jep.2018.09.004_bib104) 1975; 29 Armijos (10.1016/j.jep.2018.09.004_bib16) 2014; 10 Gakuubi (10.1016/j.jep.2018.09.004_bib70) 2012; 8 Aso (10.1016/j.jep.2018.09.004_bib18) 2012; 30 Fachner (10.1016/j.jep.2018.09.004_bib60) 2008; 17 Watts (10.1016/j.jep.2018.09.004_bib198) 2006; 332 Savo (10.1016/j.jep.2018.09.004_bib165) 2013; 9 Small (10.1016/j.jep.2018.09.004_bib177) 1976; 25 Smeriglio (10.1016/j.jep.2018.09.004_bib178) 2018; 127 Benet (10.1016/j.jep.2018.09.004_bib25) 1975 Borrelli (10.1016/j.jep.2018.09.004_bib33) 2014; 12 Adovasio (10.1016/j.jep.2018.09.004_bib4) 1996; 70 Abi-Jaoude (10.1016/j.jep.2018.09.004_bib3) 2017; 29 Hanus (10.1016/j.jep.2018.09.004_bib76) 2009; 29 O'Shaughnessy (10.1016/j.jep.2018.09.004_bib139) 1843; 5 Dragone (10.1016/j.jep.2018.09.004_bib57) 2018 Pedersen (10.1016/j.jep.2018.09.004_bib147) 2013; 35 McGinty (10.1016/j.jep.2018.09.004_bib120) 2017; 99 Babson (10.1016/j.jep.2018.09.004_bib20) 2017; 19 Opdyke (10.1016/j.jep.2018.09.004_bib138) 1983; 21 Appendino (10.1016/j.jep.2018.09.004_bib14) 2008; 71 Manca (10.1016/j.jep.2018.09.004_bib116) 2013; 62 Yang (10.1016/j.jep.2018.09.004_bib202) 1999; 148 Lim (10.1016/j.jep.2018.09.004_bib113) 2017; 15 Brenneisen (10.1016/j.jep.2018.09.004_bib35) 2007 Barratt (10.1016/j.jep.2018.09.004_bib24) 1974; 8 Ramar (10.1016/j.jep.2018.09.004_bib152) 2018; 14 Russo (10.1016/j.jep.2018.09.004_bib160) 2011; 163 Pagano (10.1016/j.jep.2018.09.004_bi |
| References_xml | – volume: 12 start-page: 254 year: 2012 end-page: 276 ident: bib107 article-title: Synthesis and pharmacological evaluation of novel 4-alkyl-5-thien-2'-yl pyrazole carboxamides publication-title: Cent. Nerv. Syst. Agents Med. Chem. – volume: 29 start-page: 349 year: 2013 end-page: 354 ident: bib93 article-title: Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells publication-title: Oncol. Rep. – volume: 325 start-page: 1007 year: 2008 end-page: 1015 ident: bib53 article-title: Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8 publication-title: J. Pharmacol. Exp. Ther. – volume: 153 start-page: 199 year: 2008 end-page: 215 ident: bib149 article-title: The diverse CB publication-title: Br. J. Pharmacol. – volume: 33 start-page: 14869 year: 2013 end-page: 14877 ident: bib5 article-title: Endocannabinoids in the brainstem modulate dural trigeminovascular nociceptive traffic via CB1 and “triptan” receptors: implications in migraine publication-title: J. Neurosci. – volume: 2016 start-page: 5962832 year: 2016 ident: bib22 article-title: Protective effect of D-limonene against oxidative stress-induced cell damage in human lens epithelial cells via the p38 pathway publication-title: Oxid. Med. Cell. Longev. – volume: 23 start-page: 337 year: 1974 end-page: 367 ident: bib169 article-title: Cannabis: an example of taxonomic neglect publication-title: Bot. Mus. Leafl. Harv. Univ. – volume: 5 start-page: 3007 year: 2016 end-page: 3017 ident: bib63 article-title: β‐caryophyllene and β‐caryophyllene oxide—natural compounds of anticancer and analgesic properties publication-title: Cancer Med. – volume: 10 start-page: 1009 year: 2015 end-page: 1012 ident: bib141 article-title: Effect of non-psychotropic plant-derived cannabinoids on bladder contractility: focus on cannabigerol publication-title: Nat. Prod. Commun. – volume: 139 start-page: 85 year: 2018 end-page: 97 ident: bib130 article-title: Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation publication-title: Neuropharmacology – volume: 4 start-page: 1614 year: 2007 end-page: 1648 ident: bib159 article-title: History of cannabis and its preparations in saga, science, and sobriquet publication-title: Chem. Biodivers. – volume: 313 start-page: 2456 year: 2015 end-page: 2473 ident: bib199 article-title: Cannabinoids for medical use: a systematic review and meta-analysis publication-title: JAMA – volume: 131 start-page: 65 year: 2003 end-page: 74 ident: bib73 article-title: Short tandem repeat (STR) DNA markers are hypervariable and informative in Cannabis sativa: implications for forensic investigations publication-title: Forensic Sci. Int. – reference: Lee, M.A., 2013. Smoke Signals: A Social History of Marijuana: Medical, Recreational and Scientific. Scribner Paperback Edition. New York. (ISBN 1439102600). – reference: Anwara, F., Latifa, S., Ashrafb, M., 2006. Analytical Characterization of Hemp (Cannabis sativa) Seed Oil from Different Agro-Ecological Zones of Pakistan, 83, pp. 323–329. 〈 – volume: 28 start-page: 280 year: 2017 end-page: 284 ident: bib36 article-title: A cannabigerol-rich Cannabis sativa extract, devoid of [INCREMENT]9-tetrahydrocannabinol, elicits hyperphagia in rats publication-title: Behav. Pharmacol. – year: 2018 ident: bib57 article-title: Crime and the legalization of recreational marijuana publication-title: J. Econ. Behav. Organ. – volume: 2 start-page: 850 year: 2015 end-page: 857 ident: bib140 article-title: In-vitro anti-cholinesterase activity of essential oil from four tropical medicinal plants publication-title: Toxicol. Rep. – year: 2018 ident: bib105 article-title: GPR3, GPR6, and GPR12 as novel molecular targets: their biological functions and interaction with cannabidiol publication-title: Acta Pharmacol. Sin. – volume: 36 start-page: 67 year: 2018 end-page: 78 ident: bib81 article-title: Systematic review of the costs and benefits of prescribed cannabis-based medicines for the management of chronic illness: lessons from multiple sclerosis publication-title: Pharmacoeconomics – volume: 234 start-page: 192 year: 2012 end-page: 204 ident: bib117 article-title: NESS038C6, a novel selective CB1 antagonist agent with anti-obesity activity and improved molecular profile publication-title: Behav. Brain Res. – volume: 359 start-page: 1 year: 1998 end-page: 18 ident: bib126 article-title: Endocannabinoids publication-title: Eur. J. Pharmacol. – volume: 9 start-page: 79 year: 1956 end-page: 90 ident: bib65 article-title: The old man of the mountain: the growth of a legend publication-title: Symp.: Q. J. Mod. Lit. – volume: 147 start-page: S163 year: 2006 end-page: S171 ident: bib148 article-title: Cannabinoid pharmacology: the first 66 years publication-title: Br. J. Pharmacol. – volume: 12 start-page: 2787 year: 2014 end-page: 2797 ident: bib33 article-title: Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid publication-title: Carcinogenesis – volume: 7 start-page: 341 year: 2016 ident: bib142 article-title: An orally active cannabis extract with high content in cannabidiol attenuates chemically-induced intestinal inflammation and hypermotility in the mouse publication-title: Front. Pharmacol. – volume: 23 start-page: 1123 year: 2014 end-page: 1140 ident: bib51 article-title: Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands publication-title: Expert Opin. Investig. Drugs – volume: 70 start-page: 777 year: 2011 end-page: 784 ident: bib71 article-title: Brain type 1 cannabinoid receptor availability in patients with anorexia and bulimia nervosa publication-title: Biol. Psychiatry – year: 2012 ident: bib111 article-title: Drugs, Behavior, and Modern Society – year: 2017 ident: bib175 article-title: Cannabinoids: biosynthesis and biotechnological applications publication-title: Cannabis sativa L. – Botany and Biotechnology – volume: 77 start-page: 1663 year: 2014 end-page: 1669 ident: bib74 article-title: Identification of endocannabinoid system-modulating N-alkylamides from Heliopsis helianthoides var. scabra and Lepidium meyenii publication-title: J. Nat. Prod. – volume: 77 start-page: 563 year: 2017 end-page: 574 ident: bib96 article-title: Delta-9-tetrahydrocannabinol/cannabidiol oromucosal spray (Sativex(®)): a review in multiple sclerosis-related spasticity publication-title: Drugs – volume: 11 start-page: 293 year: 2017 ident: bib99 article-title: Cannabinoid receptor signaling in central regulation of feeding behavior: a mini-review publication-title: Front. Neurosci. – volume: 12 start-page: 699 year: 2015 end-page: 730 ident: bib87 article-title: Molecular targets of cannabidiol in neurological disorders publication-title: Neurotherapeutics – volume: 43 start-page: 731 year: 2015 end-page: 742 ident: bib97 article-title: Alpha-pinene exhibits anti-inflammatory activity through the suppression of MAPKs and the NF-κB pathway in mouse peritoneal macrophages publication-title: Am. J. Chin. Med. – volume: 27 start-page: 667 year: 2017 end-page: 678 ident: bib108 article-title: Metabolic side effects induced by olanzapine treatment are neutralized by CB1 receptor antagonist compounds co-administration in female rats publication-title: Eur. Neuropsychopharmacol. – volume: 134 start-page: 739 year: 2011 end-page: 752 ident: bib91 article-title: "Plantas con madre": plants that teach and guide in the shamanic initiation process in the East-Central Peruvian Amazon publication-title: J. Ethnopharmacol. – volume: 11 start-page: E55 year: 2018 ident: bib84 article-title: Endocannabinoids in body weight control publication-title: Pharmaceuticals – volume: 13 start-page: 23 year: 1981 end-page: 34 ident: bib193 article-title: The religious and medicinal uses of Cannabis in China, India and Tibet publication-title: J. Psychoact. Drugs – volume: 325 start-page: 1195 year: 2002 end-page: 1198 ident: bib145 article-title: Cannabis use and mental health in young people: cohort study publication-title: BMJ – year: 2000 ident: bib101 article-title: Witchcraft in Europe, 400–1700: A Documentary History – volume: 5 start-page: 363 year: 1843 end-page: 369 ident: bib139 article-title: On the preparations of the Indian hemp, or Gunjah publication-title: Prov. Med. J. Retrosp. Med. Sci. – volume: 100 start-page: 259 year: 2011 end-page: 263 ident: bib181 article-title: Anxiolytic-like effects of inhaled linalool oxide in experimental mouse anxiety models publication-title: Pharmacol. Biochem. Behav. – volume: 7 start-page: 31 year: 2011 ident: bib134 article-title: Ethnobotany of the Monpa ethnic group at Arunachal Pradesh, India publication-title: J. Ethnobiol. Ethnomed. – volume: 57 start-page: 295 year: 2003 end-page: 323 ident: bib128 article-title: Archaeological evidence for the tradition of psychoactive plant use in the old world publication-title: Econ. Bot. – volume: 82 start-page: 1879 year: 2014 end-page: 1887 ident: bib146 article-title: Effects of cannabis on cognition in patients with MS: a psychometric and MRI study publication-title: Neurology – volume: 21 start-page: 883 year: 2014 end-page: 887 ident: bib203 article-title: Limonene inhibits methamphetamine-induced locomotor activity via regulation of 5-HT neuronal function and dopamine release publication-title: Phytomedicine – volume: 8 start-page: 299 year: 2017 ident: bib158 article-title: Cannabis and multiple sclerosis-the way forward publication-title: Front. Neurol. – volume: 17 start-page: 78 year: 2008 end-page: 103 ident: bib60 article-title: An ethno‐methodological approach to Cannabis and music perception, with EEG brain mapping in a naturalistic setting publication-title: Anthropol. Conscious. – volume: 12 start-page: 43 year: 2016 ident: bib37 article-title: A comparative ethnobotany of Khevsureti, Samtskhe-Javakheti, Tusheti, Svaneti, and Racha-Lechkhumi, Republic of Georgia (Sakartvelo), Caucasus publication-title: J. Ethnobiol. Ethnomed. – reference: Bennett, C., 2011. Early/Ancient History, in Julie Holland (Eds), The Pot Book: A Complete Guide to Cannabis, Its Role in Medicine, Politics, Science, and Culture, Rochester, Vermont, pp. 17-26. – volume: 2 start-page: 51 year: 2002 end-page: 70 ident: bib38 article-title: The medical use of cannabis among the Greeks and Romans publication-title: J. Cannabis Ther. – volume: 136 start-page: 168 year: 2017 end-page: 186 ident: bib179 article-title: Safety concerns and risk management of multiple sclerosis therapies publication-title: Acta Neurol. Scand. – volume: 436 start-page: 423 year: 2001 end-page: 429 ident: bib122 article-title: Cannabinoid receptors are absent in insects publication-title: J. Comp. Neurol. – volume: 267 start-page: 4917 year: 2000 end-page: 4927 ident: bib163 article-title: Comparative biology of the endocannabinoid system possible role in the immune response publication-title: Eur. J. Biochem. – volume: 25 start-page: 405 year: 1976 end-page: 435 ident: bib177 article-title: A practical and natural taxonomy for cannabis publication-title: Taxon – volume: 10 start-page: 9 year: 2014 ident: bib131 article-title: Ethnopharmacological practices by livestock farmers in Uganda: survey experiences from Mpigi and Gulu districts publication-title: J. Ethnobiol. Ethnomed. – volume: 66 start-page: 95 year: 2009 end-page: 105 ident: bib68 article-title: Distinct effects of {delta}9- tetrahydrocannabinol and cannabidiol on neural activation during emotional processing publication-title: Arch. Gen. Psychiatry – volume: 33 start-page: 402 year: 2018 end-page: 411 ident: bib185 article-title: Delta-9-tetrahydrocannabinol (∆(9)-THC) induce neurogenesis and improve cognitive performances of male sprague dawley rats publication-title: Neurotox. Res. – volume: 9 start-page: 18 year: 2017 ident: bib52 article-title: Analgesic-like activity of essential oil constituents: an update publication-title: Int. J. Mol. Sci. – volume: 79 start-page: 1815 year: 2010 end-page: 1826 ident: bib110 article-title: Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin publication-title: Biochem. Pharmacol. – volume: 235 start-page: 447 year: 2018 end-page: 458 ident: bib86 article-title: Phytocannabinoids modulate emotional memory processing through interactions with the ventral hippocampus and mesolimbic dopamine system: implications for neuropsychiatric pathology publication-title: Psychopharmacology – volume: 8 start-page: 39 year: 2012 ident: bib70 article-title: A survey of plants and plant products traditionally used in livestock health management in Buuri district, Meru County, Kenya publication-title: J. Ethnobiol. Ethnomed. – volume: 33 start-page: 1357 year: 2016 end-page: 1392 ident: bib77 article-title: Phytocannabinoids: a unified critical inventory publication-title: Nat. Prod. Rep. – volume: 29 start-page: 153 year: 1975 ident: bib104 publication-title: Econ. Bot. – start-page: 17 year: 2007 end-page: 49 ident: bib35 article-title: Chemistry and analysis of phytocannabinoids and other Cannabis constituents publication-title: Marijuana and the Cannabinoids. Forensic Science and Medicine – volume: 59 start-page: 926 year: 2010 end-page: 934 ident: bib95 article-title: CB1 Antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice publication-title: Diabetes – volume: 10 start-page: 26 year: 2014 ident: bib16 article-title: Traditional medicine applied by the Saraguro yachakkuna: a preliminary approach to the use of sacred and psychoactive plant species in the southern region of Ecuador publication-title: J. Ethnobiol. Ethnomed. – volume: 4 year: 2007 ident: bib190 article-title: Phytocannabinoids in Cannabis sativa: recent studies on biosynthetic enzymes publication-title: Chem. Biodivers. – volume: 113(Pt A) start-page: 199 year: 2016 end-page: 208 ident: bib157 article-title: Pure ?(9)-tetrahydrocannabivarin and a Cannabis sativa extract with high content in Δ(9)-tetrahydrocannabivarin inhibit nitrite production in murine peritoneal macrophages publication-title: Pharmacol. Res. – year: 2011 ident: bib155 article-title: Dioscorides on Pharmacy and Medicine – reference: Wilkins, S.J., 1999. Method for Treating Gastrointestinal Disorders. Patent Number: US6420435B1. 〈 – volume: 7 start-page: 19 year: 2016 ident: bib11 article-title: Cannabis sativa: the plant of the thousand and one molecules publication-title: Front. Plant Sci. – volume: 129 start-page: 154 year: 2014 end-page: 162 ident: bib64 article-title: Spasticity in patients with multiple sclerosis–clinical characteristics, treatment and quality of life publication-title: Acta Neurol. Scand. – volume: 61 start-page: 1196 year: 2003 end-page: 1203 ident: bib192 article-title: Left/right asymmetry of atrophy in semantic dementia: behavioral-cognitive implications publication-title: Neurology – volume: 175 start-page: 6 year: 2017 end-page: 22 ident: bib85 article-title: Plant glandular trichomes: natural cell factories of high biotechnological interest publication-title: Plant Physiol. – volume: 9 start-page: 9 year: 2013 ident: bib165 article-title: Plants used in artisanal fisheries on the Western Mediterranean coasts of Italy publication-title: J. Ethnobiol. Ethnomed. – volume: 6 start-page: 1 year: 2010 ident: bib115 article-title: Preparation and use of plant medicines for farmers' health in Southwest Nigeria: socio-cultural, magico-religious and economic aspects publication-title: J. Ethnobiol. Ethnomed. – volume: 47 start-page: 18 year: 2014 end-page: 23 ident: bib12 article-title: Dronabinol in severe, enduring anorexia nervosa: a randomized controlled trial publication-title: Int. J. Eat. Disord. – volume: 9 start-page: 733 year: 2018 ident: bib167 article-title: Psychedelic-assisted psychotherapy: a paradigm shift in psychiatric research and development publication-title: Front. Pharmacol. – volume: 24 start-page: 680 year: 2018 end-page: 697 ident: bib47 article-title: The use of cannabinoids in colitis: a systematic review and meta-analysis publication-title: Inflamm. Bowel Dis. – volume: 96 start-page: 5780 year: 1999 end-page: 5785 ident: bib204 article-title: Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice publication-title: Proc. Natl. Acad. Sci. – year: 2018 ident: bib186 article-title: Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study publication-title: Epilepsy Behav. – volume: 372 start-page: 686 year: 1994 end-page: 691 ident: bib56 article-title: Formation and inactivation of endogenous cannabinoid anandamide in central neurons publication-title: Nature – volume: 10 start-page: 345 year: 1982 end-page: 353 ident: bib67 article-title: The effect of chronically administered delta-9-tetrahydrocannabinol upon the polygraphically monitored sleep of normal volunteers publication-title: Drug Alcohol Depend. – year: 1980 ident: bib2 article-title: Marijuana: The First Twelve Thousand Years – volume: 18 start-page: E1739 year: 2017 ident: bib90 article-title: Speechlessness in Gilles de la Tourette syndrome: cannabis-based medicines improve severe vocal blocking tics in two patients publication-title: Int. J. Mol. Sci. – volume: 154 start-page: 1349 year: 2008 end-page: 1358 ident: bib55 article-title: Effects of delta9-tetrahydrocannabivarin on [35S]GTPgammaS binding in mouse brain cerebellum and piriform cortex membranes publication-title: Br. J. Pharmacol. – volume: 22 start-page: 415 year: 2014 end-page: 419 ident: bib201 article-title: Dronabinol for the treatment of agitation and aggressive behavior in acutely hospitalized severely demented patients with noncognitive behavioral symptoms publication-title: Am. J. Geriatr. Psychiatry – volume: 24 start-page: 515 year: 2009 end-page: 523 ident: bib48 article-title: Cannabis and anxiety: a critical review of the evidence publication-title: Hum. Psychopharmacol. – volume: 729 start-page: 67 year: 2014 end-page: 74 ident: bib188 article-title: Evaluation of selective cannabinoid CB(1) and CB(2) receptor agonists in a mouse model of lipopolysaccharide-induced interstitial cystitis publication-title: Eur. J. Pharmacol. – volume: 30 start-page: 140 year: 2018 end-page: 151 ident: bib41 article-title: Psychoactive constituents of cannabis and their clinical implications: a systematic review publication-title: Adicciones – volume: 30 start-page: 439 year: 2012 end-page: 459 ident: bib18 article-title: CB1 agonist ACEA protects neurons and reduces the cognitive impairment of AβPP/PS1 mice publication-title: J. Alzheimers Dis. – volume: 30 start-page: 14 year: 2016 end-page: 24 ident: bib187 article-title: Efficacy, tolerability, and safety of cannabinoids for chemotherapy-induced nausea and vomiting–a systematic review of systematic reviews publication-title: Schmerz – start-page: 39 year: 1975 end-page: 49 ident: bib25 article-title: Early diffusion and folk uses of hemp publication-title: Cannabis and Culture – volume: 23 start-page: 16012 year: 2016 ident: bib49 article-title: Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids publication-title: NPJ Aging Mech. Dis. – volume: 62 start-page: 256 year: 2013 end-page: 269 ident: bib116 article-title: Novel pyrazole derivatives as neutral CB₁ antagonists with significant activity towards food intake publication-title: Eur. J. Med. Chem. – volume: 68 start-page: 264 year: 2016 end-page: 355 ident: bib135 article-title: Psychedelics publication-title: Pharmacol. Rev. – volume: 2 start-page: 32 year: 1994 end-page: 37 ident: bib144 article-title: Chemical ecology of cannabis publication-title: J. Int. Hemp Assoc. – volume: 4 start-page: 87 year: 1997 end-page: 92 ident: bib123 article-title: Cannabis as repellent and pesticide publication-title: J. Int. Hemp Assoc. – volume: 8 start-page: 47 year: 1974 end-page: 54 ident: bib24 article-title: The effects of marijuana on human sleep patterns publication-title: Biol. Psychiatry – volume: 160 start-page: 677 year: 2010 end-page: 687 ident: bib29 article-title: The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice publication-title: Br. J. Pharmacol. – volume: 163 start-page: 1344 year: 2011 end-page: 1364 ident: bib160 article-title: Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects publication-title: Br. J. Pharmacol. – volume: 159 start-page: 129 year: 2010 end-page: 141 ident: bib42 article-title: Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist publication-title: Br. J. Pharmacol. – volume: 2 start-page: 167 year: 2017 end-page: 182 ident: bib133 article-title: Anti-inflammatory activity in colon models is derived from ?9-tetrahydrocannabinolic acid that interacts with additional compounds in cannabis extracts publication-title: Cannabis Cannabinoid Res. – volume: 12 start-page: e0173911 year: 2017 ident: bib32 article-title: Terpene synthases from Cannabis sativa publication-title: PLoS One – volume: 5 start-page: 46 year: 2013 end-page: 51 ident: bib54 article-title: Medical use of cannabis. Cannabidiol: a new light for schizophrenia? publication-title: Drug Test. Anal. – volume: 11 start-page: 263 year: 2002 end-page: 276 ident: bib127 article-title: The long history of Cannabis and its cultivation by the Romans in central Italy, shown by pollen records from Lago Albano and Lago di Nemi publication-title: Veget. Hist. Archaeobot. – volume: 29 start-page: 213 year: 2009 end-page: 271 ident: bib76 article-title: Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids publication-title: Med. Res. Rev. – volume: 52 start-page: 161 year: 2005 end-page: 180 ident: bib83 article-title: Genetic evidence for speciation in Cannabis (Cannabaceae) publication-title: Genet. Resour. Crop Evol. – volume: 16 start-page: 8057 year: 1996 end-page: 8066 ident: bib174 article-title: Effects of chronic treatment with delta9-tetrahydrocannabinol on cannabinoid-stimulated [35S]GTPgammaS autoradiography in rat brain publication-title: J. Neurosci. – volume: 80 start-page: 52 year: 2014 end-page: 65 ident: bib136 article-title: Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice publication-title: Pharmacol. Res. – volume: 14 start-page: 679 year: 2018 end-page: 681 ident: bib152 article-title: Medical cannabis and the treatment of obstructive sleep apnea: an American academy of sleep medicine position statement publication-title: J. Clin. Sleep. Med. – volume: 22 start-page: E1369 year: 2017 ident: bib195 article-title: Anesthetic agents of plant origin: a review of phytochemicals with anesthetic activity publication-title: Molecules – volume: 70 start-page: 526 year: 1996 end-page: 534 ident: bib4 article-title: Upper palaeolithic fibre technology: interlaced woven finds from Pavlov I, Czech Republic, c. 26,000 years ago publication-title: Antiquity – volume: 21 start-page: 661 year: 1983 end-page: 662 ident: bib138 article-title: Caryophyllene oxide publication-title: Food Chem. Toxicol. – year: 1952 ident: bib164 article-title: Agricultural Origins and Dispersals – volume: 9 start-page: 25 year: 2013 ident: bib6 article-title: Diversity and use of ethno-medicinal plants in the region of Swat, North Pakistan publication-title: J. Ethnobiol. Ethnomed. – volume: 31 start-page: 243 year: 2016 ident: bib17 article-title: CB2 cannabinoid receptor as potential target against Alzheimer's disease publication-title: Front. Neurosci. – volume: 332 start-page: 175 year: 2006 end-page: 176 ident: bib198 article-title: Cannabis confusions publication-title: BMJ: Br. Med. J. – year: 2018 ident: bib119 article-title: Cannabinoids in health and disease: pharmacological potential in metabolic syndrome and neuroinflammation publication-title: Horm. Mol. Biol. Clin. Investig. – volume: 26 start-page: 1541 year: 2016 end-page: 1555 ident: bib184 article-title: Between China and South Asia: a middle Asian corridor of crop dispersal and agricultural innovation in the bronze age publication-title: Holocene – volume: 80 start-page: 441 year: 2017 end-page: 449 ident: bib21 article-title: A review of oral cannabinoids and medical marijuana for the treatment of chemotherapy-induced nausea and vomiting: a focus on pharmacokinetic variability and pharmacodynamics publication-title: Cancer Chemother. Pharmacol. – volume: 133 start-page: 79 year: 2012 end-page: 97 ident: bib82 article-title: Phytocannabinoids as novel therapeutic agents in CNS disorders publication-title: Pharmacol. Ther. – volume: 109 start-page: 18669 year: 2012 end-page: 18673 ident: bib66 article-title: Demic and cultural neolithic diffusion publication-title: Proc. Natl. Acad. Sci. – volume: 59 start-page: 4171 year: 2008 end-page: 4182 ident: bib161 article-title: Phytochemical and genetic analyses of ancient cannabis from Central Asia publication-title: J. Exp. Bot. – volume: 2 start-page: 210 year: 2017 end-page: 216 ident: bib162 article-title: Cannabis roots: a traditional therapy with future potential for treating inflammation and pain publication-title: Cannabis Cannabinoid Res. – volume: 25 start-page: 643 year: 2002 end-page: 646 ident: bib23 article-title: Phytol, SSADH inhibitory diterpenoid of Lactuca sativa publication-title: Arch. Pharm. Res. – volume: 18 start-page: 50 year: 2018 ident: bib154 article-title: Cannabinoids for treatment of MS symptoms: state of the evidence publication-title: Curr. Neurol. Neurosci. Rep. – volume: 45 start-page: 18 year: 2004 end-page: 29 ident: bib124 article-title: Phylogenomic and chemotaxonomic analysis of the endocannabinoid system publication-title: Brain Res. Brain Res. Rev. – volume: 174 start-page: 2682 year: 2017 end-page: 2695 ident: bib168 article-title: Cannabinoid CB(1) /CB(2) receptor agonists attenuate hyperactivity and body weight loss in a rat model of activity-based anorexia publication-title: Br. J. Pharmacol. – volume: 33 start-page: 138 year: 2012 end-page: 146 ident: bib79 article-title: Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro publication-title: Neurotoxicology – volume: 32 start-page: 468 year: 2014 end-page: 474 ident: bib132 article-title: Cannabis for inflammatory bowel disease publication-title: Dig. Dis. – volume: 5 start-page: 114 year: 2015 end-page: 125 ident: bib191 article-title: GCMS analysis of Cannabis sativa L. from four different areas of Pakistan publication-title: Egypt. J. Forensic Sci. – volume: 74 start-page: 94 year: 2013 end-page: 108 ident: bib118 article-title: NESS06SM reduces body weight with an improved profile relative to SR141716A publication-title: Pharmacol. Res. – volume: 63 start-page: 432 year: 2013 end-page: 437 ident: bib173 article-title: The effect of cannabichromene on adult neural stem/progenitor cells publication-title: Neurochem. Int. – volume: 90 year: 2018 ident: bib15 article-title: Cannabidiol based medical cannabis in children with autism- a retrospective feasibility study (P3.318) publication-title: Neurology – volume: 60 start-page: 2331 year: 2013 end-page: 2342 ident: bib150 publication-title: Genet. Resour. Crop Evol. – volume: 87 start-page: 33 year: 2016 end-page: 44 ident: bib189 article-title: Comparing hemp (Cannabis sativa L.) cultivars for dual-purpose production under contrasting environments publication-title: Ind. Crops Prod. – volume: 28 start-page: 61 year: 1980 end-page: 69 ident: bib10 article-title: Leaf variation among cannabis species from a controlled garden publication-title: Harv. Univ. Bot. Mus. Leafl. – volume: 11 start-page: 329 year: 2017 end-page: 337 ident: bib80 article-title: Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go? publication-title: Expert Rev. Gastroenterol. Hepatol. – volume: 19 year: 2014 ident: bib72 article-title: Cannabinoids: new promising agents in the treatment of neurological diseases publication-title: Molecules – volume: 83 start-page: 393 year: 1998 end-page: 411 ident: bib194 article-title: Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system publication-title: Neuroscience – volume: 148 start-page: 79 year: 1999 end-page: 82 ident: bib202 article-title: Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis publication-title: Mycopathologia – volume: 30 start-page: 515 year: 2009 end-page: 527 ident: bib89 article-title: Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb publication-title: Trends Pharmacol. Sci. – volume: 100 start-page: 328 year: 1990 end-page: 333 ident: bib43 article-title: Subjective and behavioral effects of marijuana the morning after smoking publication-title: Psychopharmacology – volume: 103 start-page: 712 year: 2008 end-page: 720 ident: bib75 article-title: The contribution of research to the development of a national cannabis policy in Australia publication-title: Addiction – volume: 8 start-page: 95 year: 2010 end-page: 97 ident: bib59 article-title: A natural approach to soothing atopic skin publication-title: Skinmed – volume: 29 start-page: 391 year: 2017 end-page: 400 ident: bib3 article-title: Preliminary evidence on cannabis effectiveness and tolerability for adults with tourette syndrome publication-title: J. Neuropsychiatry Clin. Neurosci. – start-page: 3 year: 2017 end-page: 12 ident: bib61 article-title: The cannabis plant: botanical aspects publication-title: Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment – volume: 232 start-page: 1123 year: 2015 end-page: 1134 ident: bib102 article-title: Cannabis and creativity: highly potent cannabis impairs divergent thinking in regular cannabis users publication-title: Psychopharmacology – volume: 11 start-page: 135 year: 1984 end-page: 156 ident: bib114 article-title: The concept of plants as teachers among four mestizo shamans of Iquitos, northeastern Peru publication-title: J. Ethnopharmacol. – volume: 71 start-page: 1427 year: 2008 end-page: 1430 ident: bib14 article-title: Antibacterial cannabinoids from Cannabis sativa: a structure-activity study publication-title: J. Nat. Prod. – start-page: 29 year: 1998 end-page: 54 ident: bib151 article-title: The Cannabis plant: botany, cultivation, and processing for use publication-title: Cannabis: The Genus Cannabis – volume: 80 start-page: 437 year: 2017 end-page: 475 ident: bib183 article-title: Cannabinoids and pain: sites and mechanisms of action publication-title: Adv. Pharmacol. – volume: 1 start-page: 81 year: 2008 end-page: 98 ident: bib180 article-title: The chronic effects of cannabis on memory in humans: a review publication-title: Curr. Drug Abus. Rev. – volume: 23 start-page: 782 year: 2017 end-page: 787 ident: bib28 article-title: A chronic low dose of Δ(9)-tetrahydrocannabinol (THC) restores cognitive function in old mice publication-title: Nat. Med. – volume: 35 start-page: 17 year: 2013 end-page: 32 ident: bib147 article-title: The medicalisation of revolt: a sociological analysis of medical cannabis users publication-title: Sociol. Health Illn. – volume: 55 start-page: 63 year: 2017 end-page: 67 ident: bib182 article-title: Antinociceptive and anticonvulsant effects of the monoterpene linalool oxide publication-title: Pharm. Biol. – volume: 17 start-page: 145 year: 2014 end-page: 149 ident: bib50 article-title: Anti-stress effects of d-limonene and its metabolite perillyl alcohol publication-title: Rejuvenation Res. – start-page: 35 year: 1997 end-page: 55 ident: bib7 article-title: History of therapeutic cannabis publication-title: Cannabis in Medical Practice: A Legal, Historical and Pharmacological Overview of the Therapeutic use of Marijuana – volume: 35 start-page: 847 year: 2013 end-page: 858 ident: bib19 article-title: CB2 cannabinoid receptor agonist ameliorates Alzheimer-like phenotype in AβPP/PS1 mice publication-title: J. Alzheimers Dis. – reference: 〉. – volume: 185 start-page: 524 year: 2006 end-page: 528 ident: bib197 article-title: Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia publication-title: Psychopharmacology – volume: 1 start-page: 28 year: 2013 end-page: 38 ident: bib40 article-title: Psychoactive plants in ancient Greece publication-title: Neurosci. Hist. – year: 2018 ident: bib62 article-title: The biomedical challenge of neurodegenerative disorders: an opportunity for cannabinoid-based therapies to improve on the poor current therapeutic outcomes publication-title: Br. J. Pharmacol. – volume: 64 start-page: e78 year: 2018 end-page: e94 ident: bib8 article-title: Systematic review of systematic reviews for medical cannabinoids: pain, nausea and vomiting, spasticity, and harms publication-title: Can. Fam. Physician – volume: 217 start-page: 432 year: 2011 end-page: 438 ident: bib106 article-title: Weight loss induced by rimonabant is associated with an altered leptin expression and hypothalamic leptin signaling in diet-induced obese mice publication-title: Behav. Brain Res. – volume: 81 start-page: 189 year: 2015 end-page: 294 ident: bib176 article-title: Evolution and classification of Cannabis sativa (Marijuana, Hemp) in relation to human utilization publication-title: Bot. Rev. – volume: 6 start-page: 58 year: 2016 ident: bib44 article-title: Industrial hemp in North America: production, politics and potential publication-title: Agronomy – volume: 24 start-page: 608 year: 2014 end-page: 620 ident: bib98 article-title: The cannabinoid CB 2 receptor‐selective phytocannabinoid beta‐caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain publication-title: Eur. Neuropsychopharmacol. – volume: 3 start-page: 182 year: 2012 end-page: 186 ident: bib153 article-title: The first dual ChE/FAAH inhibitors: new perspectives for alzheimer's disease? publication-title: ACS Med. Chem. Lett. – year: 1992 ident: bib121 article-title: Food of the Gods: The Search for the Original Tree of Knowledge – A Radical History of Plants, Drugs, and Human Evolution – volume: 15 start-page: 301 year: 2017 end-page: 312 ident: bib113 article-title: A systematic review of the effectiveness of medical cannabis for psychiatric, movement and neurodegenerative disorders publication-title: Clin. Psychopharmacol. Neurosci. – volume: 722 start-page: 134 year: 2014 end-page: 146 ident: bib172 article-title: Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system publication-title: Eur. J. Pharmacol. – volume: 20 start-page: 461 year: 1995 end-page: 465 ident: bib58 article-title: Effects of linalool on glutamatergic system in the rat cerebral cortex publication-title: Neurochem. Res. – start-page: 92 year: 1992 end-page: 101 ident: bib170 article-title: Plants of the Gods – Their Sacred, Healing and Hallucinogenic Powers – volume: 108 start-page: 414 year: 2006 end-page: 422 ident: bib94 article-title: A new insight into Cannabis sativa (Cannabaceae) utilization from 2500-year-old Yanghai Tombs, Xinjiang, China publication-title: J. Ethnopharmacol. – reference: Brecher, E.M., Editors of Consumer Reports Magazine, 1972. The Consumers Union Report on Licit and Illicit Drugs. Schaffer Library of Drug Policy. (ISBN 0316153400). 〈 – volume: 28 start-page: 177 year: 2009 end-page: 190 ident: bib196 article-title: The signs of the sacred: identifying shamans using archaeological evidence publication-title: J. Anthropol. Archaeol. – volume: 6 start-page: 35 year: 2010 ident: bib103 article-title: Traditional herbal medicine in far-west Nepal: a pharmacological appraisal publication-title: J. Ethnobiol. Ethnomed. – volume: 82 start-page: 1556 year: 2014 end-page: 1563 ident: bib100 article-title: Systematic review: efficacy and safety of medical marijuana in selected neurologic disorders: report of the Guideline Development Subcommittee of the American Academy of Neurology publication-title: Neurology – volume: 40 year: 2017 ident: bib39 article-title: Effects of cannabinoid agonists and antagonists on sleep and breathing in Sprague-Dawley rats publication-title: Sleep – volume: 28 start-page: 437 year: 1974 end-page: 448 ident: bib112 article-title: An archaeological and historical account of Cannabis in China publication-title: Econ. Bot. – volume: 127 start-page: 101 year: 2018 end-page: 108 ident: bib178 article-title: Inhibition of aldose reductase activity by Cannabis sativa chemotypes extracts with high content of cannabidiol or cannabigerol publication-title: Fitoterapia – volume: 5 year: 2013 ident: bib69 article-title: Persons as plants: ecopsychology and the return to the dream of nature publication-title: Landsc.: J. Int. Cent. Landsc. Lang. – volume: 72 start-page: 1279 year: 2015 end-page: 1284 ident: bib27 article-title: Use and effects of cannabinoids in military veterans with posttraumatic stress disorder publication-title: Am. J. Health Syst. Pharm. – year: 1974 ident: bib31 article-title: The Marijuana Conviction: A History of Marijuana Prohibition in the United States – volume: 87 start-page: 3273 year: 1965 end-page: 3275 ident: bib125 article-title: A total synthesis of dl-delta-1-tetrahydrocannabinol, the active constituent of hashish publication-title: J. Am. Chem. Soc. – start-page: 60 year: 2013 end-page: 66 ident: bib45 article-title: Cannabis, Evolution and Ethnobotany – year: 1973 ident: bib129 article-title: Hashish and Mental Illness (1845) – volume: 10 start-page: e0129618 year: 2015 ident: bib166 article-title: Cannabinoid CB2 receptors in a mouse model of Aβ amyloidosis: immunohistochemical analysis and suitability as a PET biomarker of neuroinflammation publication-title: PLoS One – volume: 99 start-page: 80 year: 2017 end-page: 86 ident: bib120 article-title: Public perceptions of arguments supporting and opposing recreational marijuana legalization publication-title: Prev. Med. – volume: 18 start-page: 8 year: 2018 ident: bib137 article-title: The use of cannabis and cannabinoids in treating symptoms of multiple sclerosis: a systematic review of reviews publication-title: Curr. Neurol. Neurosci. Rep. – volume: 32 start-page: 567 year: 2018 end-page: 576 ident: bib171 article-title: Cannabinoids for nausea and vomiting related to chemotherapy: overview of systematic reviews publication-title: Phytother. Res. – year: 2005 ident: bib9 article-title: Diagnoses in Assyrian and Babylonian Medicine – volume: 110 start-page: 44 year: 2016 end-page: 49 ident: bib46 article-title: Cannabis taxonomy: the ‘Sativa’ Vs. ‘Indica’ debate publication-title: HerbalGram – volume: 154 start-page: 745 year: 2014 end-page: 752 ident: bib92 article-title: Hempseed oil induces reactive oxygen species- and C/EBP homologous protein-mediated apoptosis in MH7A human rheumatoid arthritis fibroblast-like synovial cells publication-title: J. Ethnopharmacol. – volume: 52 start-page: 72 year: 2002 end-page: 91 ident: bib88 article-title: Cancer anorexia-cachexia syndrome: current issues in research and management publication-title: CA Cancer J. Clin. – volume: 26 start-page: 2832 year: 2016 end-page: 2849 ident: bib30 article-title: Cortical structure alterations and social behavior impairment in p50-deficient mice publication-title: Cereb. Cortex – volume: 9 start-page: 84 year: 2013 ident: bib1 article-title: Botanical ethnoveterinary therapies in three districts of the Lesser Himalayas of Pakistan publication-title: J. Ethnobiol. Ethnomed. – volume: 169 start-page: 213 year: 2013 end-page: 229 ident: bib156 article-title: The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis publication-title: Br. J. Pharmacol. – volume: 6 start-page: 4 year: 2010 ident: bib143 article-title: Indigenous knowledge of medicinal plants used by Saperas community of Khetawas, Jhajjar District, Haryana, India publication-title: J. Ethnobiol. Ethnomed. – volume: 19 start-page: 23 year: 2017 ident: bib20 article-title: Cannabis, cannabinoids, and sleep: a review of the literature publication-title: Curr. Psychiatry Rep. – volume: 87 start-page: 51 year: 2013 end-page: 59 ident: bib78 article-title: Analysis of cannabinoids in laser-microdissected trichomes of medicinal publication-title: Phytochemistry – volume: 2 start-page: 167 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib133 article-title: Anti-inflammatory activity in colon models is derived from ?9-tetrahydrocannabinolic acid that interacts with additional compounds in cannabis extracts publication-title: Cannabis Cannabinoid Res. doi: 10.1089/can.2017.0027 – volume: 19 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib72 article-title: Cannabinoids: new promising agents in the treatment of neurological diseases publication-title: Molecules doi: 10.3390/molecules191118781 – volume: 4 start-page: 87 year: 1997 ident: 10.1016/j.jep.2018.09.004_bib123 article-title: Cannabis as repellent and pesticide publication-title: J. Int. Hemp Assoc. – volume: 68 start-page: 264 issue: 2 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib135 article-title: Psychedelics publication-title: Pharmacol. Rev. doi: 10.1124/pr.115.011478 – volume: 17 start-page: 145 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib50 article-title: Anti-stress effects of d-limonene and its metabolite perillyl alcohol publication-title: Rejuvenation Res. doi: 10.1089/rej.2013.1515 – volume: 28 start-page: 61 year: 1980 ident: 10.1016/j.jep.2018.09.004_bib10 article-title: Leaf variation among cannabis species from a controlled garden publication-title: Harv. Univ. Bot. Mus. Leafl. doi: 10.5962/p.168641 – volume: 30 start-page: 515 year: 2009 ident: 10.1016/j.jep.2018.09.004_bib89 article-title: Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb publication-title: Trends Pharmacol. Sci. doi: 10.1016/j.tips.2009.07.006 – volume: 29 start-page: 153 year: 1975 ident: 10.1016/j.jep.2018.09.004_bib104 publication-title: Econ. Bot. doi: 10.1007/BF02863315 – volume: 52 start-page: 72 year: 2002 ident: 10.1016/j.jep.2018.09.004_bib88 article-title: Cancer anorexia-cachexia syndrome: current issues in research and management publication-title: CA Cancer J. Clin. doi: 10.3322/canjclin.52.2.72 – volume: 52 start-page: 161 year: 2005 ident: 10.1016/j.jep.2018.09.004_bib83 article-title: Genetic evidence for speciation in Cannabis (Cannabaceae) publication-title: Genet. Resour. Crop Evol. doi: 10.1007/s10722-003-4452-y – volume: 313 start-page: 2456 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib199 article-title: Cannabinoids for medical use: a systematic review and meta-analysis publication-title: JAMA doi: 10.1001/jama.2015.6358 – volume: 80 start-page: 437 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib183 article-title: Cannabinoids and pain: sites and mechanisms of action publication-title: Adv. Pharmacol. doi: 10.1016/bs.apha.2017.05.003 – volume: 154 start-page: 745 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib92 article-title: Hempseed oil induces reactive oxygen species- and C/EBP homologous protein-mediated apoptosis in MH7A human rheumatoid arthritis fibroblast-like synovial cells publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2014.04.052 – volume: 108 start-page: 414 year: 2006 ident: 10.1016/j.jep.2018.09.004_bib94 article-title: A new insight into Cannabis sativa (Cannabaceae) utilization from 2500-year-old Yanghai Tombs, Xinjiang, China publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2006.05.034 – volume: 2 start-page: 32 issue: 29 year: 1994 ident: 10.1016/j.jep.2018.09.004_bib144 article-title: Chemical ecology of cannabis publication-title: J. Int. Hemp Assoc. – volume: 10 start-page: 345 year: 1982 ident: 10.1016/j.jep.2018.09.004_bib67 article-title: The effect of chronically administered delta-9-tetrahydrocannabinol upon the polygraphically monitored sleep of normal volunteers publication-title: Drug Alcohol Depend. doi: 10.1016/0376-8716(82)90036-9 – volume: 169 start-page: 213 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib156 article-title: The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis publication-title: Br. J. Pharmacol. doi: 10.1111/bph.12120 – volume: 35 start-page: 17 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib147 article-title: The medicalisation of revolt: a sociological analysis of medical cannabis users publication-title: Sociol. Health Illn. doi: 10.1111/j.1467-9566.2012.01476.x – volume: 6 start-page: 58 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib44 article-title: Industrial hemp in North America: production, politics and potential publication-title: Agronomy doi: 10.3390/agronomy6040058 – volume: 29 start-page: 213 year: 2009 ident: 10.1016/j.jep.2018.09.004_bib76 article-title: Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids publication-title: Med. Res. Rev. doi: 10.1002/med.20135 – volume: 29 start-page: 391 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib3 article-title: Preliminary evidence on cannabis effectiveness and tolerability for adults with tourette syndrome publication-title: J. Neuropsychiatry Clin. Neurosci. doi: 10.1176/appi.neuropsych.16110310 – volume: 174 start-page: 2682 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib168 article-title: Cannabinoid CB(1) /CB(2) receptor agonists attenuate hyperactivity and body weight loss in a rat model of activity-based anorexia publication-title: Br. J. Pharmacol. doi: 10.1111/bph.13892 – volume: 87 start-page: 33 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib189 article-title: Comparing hemp (Cannabis sativa L.) cultivars for dual-purpose production under contrasting environments publication-title: Ind. Crops Prod. doi: 10.1016/j.indcrop.2016.04.026 – volume: 72 start-page: 1279 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib27 article-title: Use and effects of cannabinoids in military veterans with posttraumatic stress disorder publication-title: Am. J. Health Syst. Pharm. doi: 10.2146/ajhp140523 – volume: 11 start-page: 135 year: 1984 ident: 10.1016/j.jep.2018.09.004_bib114 article-title: The concept of plants as teachers among four mestizo shamans of Iquitos, northeastern Peru publication-title: J. Ethnopharmacol. doi: 10.1016/0378-8741(84)90036-9 – volume: 30 start-page: 14 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib187 article-title: Efficacy, tolerability, and safety of cannabinoids for chemotherapy-induced nausea and vomiting–a systematic review of systematic reviews publication-title: Schmerz doi: 10.1007/s00482-015-0092-3 – volume: 8 start-page: 299 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib158 article-title: Cannabis and multiple sclerosis-the way forward publication-title: Front. Neurol. doi: 10.3389/fneur.2017.00299 – volume: 5 start-page: 114 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib191 article-title: GCMS analysis of Cannabis sativa L. from four different areas of Pakistan publication-title: Egypt. J. Forensic Sci. doi: 10.1016/j.ejfs.2014.07.008 – volume: 30 start-page: 439 year: 2012 ident: 10.1016/j.jep.2018.09.004_bib18 article-title: CB1 agonist ACEA protects neurons and reduces the cognitive impairment of AβPP/PS1 mice publication-title: J. Alzheimers Dis. doi: 10.3233/JAD-2012-111862 – volume: 133 start-page: 79 year: 2012 ident: 10.1016/j.jep.2018.09.004_bib82 article-title: Phytocannabinoids as novel therapeutic agents in CNS disorders publication-title: Pharmacol. Ther. doi: 10.1016/j.pharmthera.2011.09.002 – volume: 59 start-page: 4171 year: 2008 ident: 10.1016/j.jep.2018.09.004_bib161 article-title: Phytochemical and genetic analyses of ancient cannabis from Central Asia publication-title: J. Exp. Bot. doi: 10.1093/jxb/ern260 – volume: 79 start-page: 1815 year: 2010 ident: 10.1016/j.jep.2018.09.004_bib110 article-title: Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin publication-title: Biochem. Pharmacol. doi: 10.1016/j.bcp.2010.02.015 – volume: 9 start-page: 18 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib52 article-title: Analgesic-like activity of essential oil constituents: an update publication-title: Int. J. Mol. Sci. – volume: 235 start-page: 447 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib86 article-title: Phytocannabinoids modulate emotional memory processing through interactions with the ventral hippocampus and mesolimbic dopamine system: implications for neuropsychiatric pathology publication-title: Psychopharmacology doi: 10.1007/s00213-017-4766-7 – volume: 6 start-page: 1 year: 2010 ident: 10.1016/j.jep.2018.09.004_bib115 article-title: Preparation and use of plant medicines for farmers' health in Southwest Nigeria: socio-cultural, magico-religious and economic aspects publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-6-1 – volume: 13 start-page: 23 year: 1981 ident: 10.1016/j.jep.2018.09.004_bib193 article-title: The religious and medicinal uses of Cannabis in China, India and Tibet publication-title: J. Psychoact. Drugs doi: 10.1080/02791072.1981.10471447 – year: 1952 ident: 10.1016/j.jep.2018.09.004_bib164 – year: 2005 ident: 10.1016/j.jep.2018.09.004_bib9 – volume: 24 start-page: 680 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib47 article-title: The use of cannabinoids in colitis: a systematic review and meta-analysis publication-title: Inflamm. Bowel Dis. doi: 10.1093/ibd/izy014 – volume: 45 start-page: 18 year: 2004 ident: 10.1016/j.jep.2018.09.004_bib124 article-title: Phylogenomic and chemotaxonomic analysis of the endocannabinoid system publication-title: Brain Res. Brain Res. Rev. doi: 10.1016/j.brainresrev.2003.11.005 – volume: 32 start-page: 468 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib132 article-title: Cannabis for inflammatory bowel disease publication-title: Dig. Dis. doi: 10.1159/000358155 – volume: 18 start-page: 8 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib137 article-title: The use of cannabis and cannabinoids in treating symptoms of multiple sclerosis: a systematic review of reviews publication-title: Curr. Neurol. Neurosci. Rep. doi: 10.1007/s11910-018-0814-x – year: 2018 ident: 10.1016/j.jep.2018.09.004_bib186 article-title: Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study publication-title: Epilepsy Behav. doi: 10.1016/j.yebeh.2018.07.020 – year: 2000 ident: 10.1016/j.jep.2018.09.004_bib101 – volume: 27 start-page: 667 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib108 article-title: Metabolic side effects induced by olanzapine treatment are neutralized by CB1 receptor antagonist compounds co-administration in female rats publication-title: Eur. Neuropsychopharmacol. doi: 10.1016/j.euroneuro.2017.03.010 – volume: 9 start-page: 84 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib1 article-title: Botanical ethnoveterinary therapies in three districts of the Lesser Himalayas of Pakistan publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-9-84 – start-page: 60 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib45 – volume: 87 start-page: 3273 year: 1965 ident: 10.1016/j.jep.2018.09.004_bib125 article-title: A total synthesis of dl-delta-1-tetrahydrocannabinol, the active constituent of hashish publication-title: J. Am. Chem. Soc. doi: 10.1021/ja01092a065 – year: 2017 ident: 10.1016/j.jep.2018.09.004_bib175 article-title: Cannabinoids: biosynthesis and biotechnological applications – volume: 28 start-page: 177 year: 2009 ident: 10.1016/j.jep.2018.09.004_bib196 article-title: The signs of the sacred: identifying shamans using archaeological evidence publication-title: J. Anthropol. Archaeol. doi: 10.1016/j.jaa.2009.02.003 – volume: 70 start-page: 526 year: 1996 ident: 10.1016/j.jep.2018.09.004_bib4 article-title: Upper palaeolithic fibre technology: interlaced woven finds from Pavlov I, Czech Republic, c. 26,000 years ago publication-title: Antiquity doi: 10.1017/S0003598X0008368X – volume: 3 start-page: 182 year: 2012 ident: 10.1016/j.jep.2018.09.004_bib153 article-title: The first dual ChE/FAAH inhibitors: new perspectives for alzheimer's disease? publication-title: ACS Med. Chem. Lett. doi: 10.1021/ml200313p – volume: 11 start-page: 329 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib80 article-title: Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go? publication-title: Expert Rev. Gastroenterol. Hepatol. doi: 10.1080/17474124.2017.1292851 – ident: 10.1016/j.jep.2018.09.004_bib13 doi: 10.1007/s11746-006-1207-x – volume: 26 start-page: 2832 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib30 article-title: Cortical structure alterations and social behavior impairment in p50-deficient mice publication-title: Cereb. Cortex doi: 10.1093/cercor/bhw037 – volume: 154 start-page: 1349 year: 2008 ident: 10.1016/j.jep.2018.09.004_bib55 article-title: Effects of delta9-tetrahydrocannabivarin on [35S]GTPgammaS binding in mouse brain cerebellum and piriform cortex membranes publication-title: Br. J. Pharmacol. doi: 10.1038/bjp.2008.190 – volume: 23 start-page: 1123 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib51 article-title: Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands publication-title: Expert Opin. Investig. Drugs doi: 10.1517/13543784.2014.918603 – volume: 332 start-page: 175 year: 2006 ident: 10.1016/j.jep.2018.09.004_bib198 article-title: Cannabis confusions publication-title: BMJ: Br. Med. J. doi: 10.1136/bmj.332.7534.175 – volume: 163 start-page: 1344 year: 2011 ident: 10.1016/j.jep.2018.09.004_bib160 article-title: Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects publication-title: Br. J. Pharmacol. doi: 10.1111/j.1476-5381.2011.01238.x – volume: 9 start-page: 25 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib6 article-title: Diversity and use of ethno-medicinal plants in the region of Swat, North Pakistan publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-9-25 – volume: 1 start-page: 28 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib40 article-title: Psychoactive plants in ancient Greece publication-title: Neurosci. Hist. – volume: 131 start-page: 65 year: 2003 ident: 10.1016/j.jep.2018.09.004_bib73 article-title: Short tandem repeat (STR) DNA markers are hypervariable and informative in Cannabis sativa: implications for forensic investigations publication-title: Forensic Sci. Int. doi: 10.1016/S0379-0738(02)00397-3 – volume: 11 start-page: 263 year: 2002 ident: 10.1016/j.jep.2018.09.004_bib127 article-title: The long history of Cannabis and its cultivation by the Romans in central Italy, shown by pollen records from Lago Albano and Lago di Nemi publication-title: Veget. Hist. Archaeobot. doi: 10.1007/s003340200039 – volume: 6 start-page: 4 year: 2010 ident: 10.1016/j.jep.2018.09.004_bib143 article-title: Indigenous knowledge of medicinal plants used by Saperas community of Khetawas, Jhajjar District, Haryana, India publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-6-4 – volume: 47 start-page: 18 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib12 article-title: Dronabinol in severe, enduring anorexia nervosa: a randomized controlled trial publication-title: Int. J. Eat. Disord. doi: 10.1002/eat.22173 – volume: 40 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib39 article-title: Effects of cannabinoid agonists and antagonists on sleep and breathing in Sprague-Dawley rats publication-title: Sleep doi: 10.1093/sleep/zsx112 – volume: 28 start-page: 437 year: 1974 ident: 10.1016/j.jep.2018.09.004_bib112 article-title: An archaeological and historical account of Cannabis in China publication-title: Econ. Bot. doi: 10.1007/BF02862859 – volume: 234 start-page: 192 year: 2012 ident: 10.1016/j.jep.2018.09.004_bib117 article-title: NESS038C6, a novel selective CB1 antagonist agent with anti-obesity activity and improved molecular profile publication-title: Behav. Brain Res. doi: 10.1016/j.bbr.2012.06.033 – year: 2011 ident: 10.1016/j.jep.2018.09.004_bib155 – volume: 372 start-page: 686 year: 1994 ident: 10.1016/j.jep.2018.09.004_bib56 article-title: Formation and inactivation of endogenous cannabinoid anandamide in central neurons publication-title: Nature doi: 10.1038/372686a0 – volume: 57 start-page: 295 year: 2003 ident: 10.1016/j.jep.2018.09.004_bib128 article-title: Archaeological evidence for the tradition of psychoactive plant use in the old world publication-title: Econ. Bot. doi: 10.1663/0013-0001(2003)057[0295:AEFTTO]2.0.CO;2 – start-page: 92 year: 1992 ident: 10.1016/j.jep.2018.09.004_bib170 – volume: 33 start-page: 1357 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib77 article-title: Phytocannabinoids: a unified critical inventory publication-title: Nat. Prod. Rep. doi: 10.1039/C6NP00074F – volume: 148 start-page: 79 year: 1999 ident: 10.1016/j.jep.2018.09.004_bib202 article-title: Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis publication-title: Mycopathologia doi: 10.1023/A:1007178924408 – volume: 66 start-page: 95 year: 2009 ident: 10.1016/j.jep.2018.09.004_bib68 article-title: Distinct effects of {delta}9- tetrahydrocannabinol and cannabidiol on neural activation during emotional processing publication-title: Arch. Gen. Psychiatry doi: 10.1001/archgenpsychiatry.2008.519 – volume: 127 start-page: 101 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib178 article-title: Inhibition of aldose reductase activity by Cannabis sativa chemotypes extracts with high content of cannabidiol or cannabigerol publication-title: Fitoterapia doi: 10.1016/j.fitote.2018.02.002 – volume: 14 start-page: 679 issue: 4 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib152 article-title: Medical cannabis and the treatment of obstructive sleep apnea: an American academy of sleep medicine position statement publication-title: J. Clin. Sleep. Med. doi: 10.5664/jcsm.7070 – ident: 10.1016/j.jep.2018.09.004_bib26 – start-page: 35 year: 1997 ident: 10.1016/j.jep.2018.09.004_bib7 article-title: History of therapeutic cannabis – year: 2018 ident: 10.1016/j.jep.2018.09.004_bib57 article-title: Crime and the legalization of recreational marijuana publication-title: J. Econ. Behav. Organ. doi: 10.1016/j.jebo.2018.02.005 – year: 2018 ident: 10.1016/j.jep.2018.09.004_bib119 article-title: Cannabinoids in health and disease: pharmacological potential in metabolic syndrome and neuroinflammation publication-title: Horm. Mol. Biol. Clin. Investig. doi: 10.1515/hmbci-2018-0013 – volume: 87 start-page: 51 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib78 article-title: Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR publication-title: Phytochemistry doi: 10.1016/j.phytochem.2012.11.001 – volume: 6 start-page: 35 year: 2010 ident: 10.1016/j.jep.2018.09.004_bib103 article-title: Traditional herbal medicine in far-west Nepal: a pharmacological appraisal publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-6-35 – volume: 10 start-page: 9 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib131 article-title: Ethnopharmacological practices by livestock farmers in Uganda: survey experiences from Mpigi and Gulu districts publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-10-9 – year: 2018 ident: 10.1016/j.jep.2018.09.004_bib105 article-title: GPR3, GPR6, and GPR12 as novel molecular targets: their biological functions and interaction with cannabidiol publication-title: Acta Pharmacol. Sin. doi: 10.1038/s41401-018-0031-9 – volume: 2 start-page: 51 year: 2002 ident: 10.1016/j.jep.2018.09.004_bib38 article-title: The medical use of cannabis among the Greeks and Romans publication-title: J. Cannabis Ther. doi: 10.1300/J175v02n02_04 – year: 1992 ident: 10.1016/j.jep.2018.09.004_bib121 – volume: 232 start-page: 1123 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib102 article-title: Cannabis and creativity: highly potent cannabis impairs divergent thinking in regular cannabis users publication-title: Psychopharmacology doi: 10.1007/s00213-014-3749-1 – volume: 325 start-page: 1007 year: 2008 ident: 10.1016/j.jep.2018.09.004_bib53 article-title: Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8 publication-title: J. Pharmacol. Exp. Ther. doi: 10.1124/jpet.107.134809 – volume: 8 start-page: 39 year: 2012 ident: 10.1016/j.jep.2018.09.004_bib70 article-title: A survey of plants and plant products traditionally used in livestock health management in Buuri district, Meru County, Kenya publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-8-39 – volume: 113(Pt A) start-page: 199 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib157 article-title: Pure ?(9)-tetrahydrocannabivarin and a Cannabis sativa extract with high content in Δ(9)-tetrahydrocannabivarin inhibit nitrite production in murine peritoneal macrophages publication-title: Pharmacol. Res. doi: 10.1016/j.phrs.2016.07.045 – volume: 82 start-page: 1879 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib146 article-title: Effects of cannabis on cognition in patients with MS: a psychometric and MRI study publication-title: Neurology doi: 10.1212/WNL.0000000000000446 – volume: 5 start-page: 3007 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib63 article-title: β‐caryophyllene and β‐caryophyllene oxide—natural compounds of anticancer and analgesic properties publication-title: Cancer Med. doi: 10.1002/cam4.816 – volume: 11 start-page: E55 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib84 article-title: Endocannabinoids in body weight control publication-title: Pharmaceuticals doi: 10.3390/ph11020055 – volume: 77 start-page: 563 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib96 article-title: Delta-9-tetrahydrocannabinol/cannabidiol oromucosal spray (Sativex(®)): a review in multiple sclerosis-related spasticity publication-title: Drugs doi: 10.1007/s40265-017-0720-6 – volume: 729 start-page: 67 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib188 article-title: Evaluation of selective cannabinoid CB(1) and CB(2) receptor agonists in a mouse model of lipopolysaccharide-induced interstitial cystitis publication-title: Eur. J. Pharmacol. doi: 10.1016/j.ejphar.2014.02.013 – volume: 32 start-page: 567 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib171 article-title: Cannabinoids for nausea and vomiting related to chemotherapy: overview of systematic reviews publication-title: Phytother. Res. doi: 10.1002/ptr.5975 – volume: 23 start-page: 782 issue: 6 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib28 article-title: A chronic low dose of Δ(9)-tetrahydrocannabinol (THC) restores cognitive function in old mice publication-title: Nat. Med. doi: 10.1038/nm.4311 – volume: 18 start-page: 50 issue: 8 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib154 article-title: Cannabinoids for treatment of MS symptoms: state of the evidence publication-title: Curr. Neurol. Neurosci. Rep. doi: 10.1007/s11910-018-0859-x – volume: 21 start-page: 661 year: 1983 ident: 10.1016/j.jep.2018.09.004_bib138 article-title: Caryophyllene oxide publication-title: Food Chem. Toxicol. doi: 10.1016/0278-6915(83)90161-8 – volume: 2016 start-page: 5962832 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib22 article-title: Protective effect of D-limonene against oxidative stress-induced cell damage in human lens epithelial cells via the p38 pathway publication-title: Oxid. Med. Cell. Longev. doi: 10.1155/2016/5962832 – volume: 217 start-page: 432 year: 2011 ident: 10.1016/j.jep.2018.09.004_bib106 article-title: Weight loss induced by rimonabant is associated with an altered leptin expression and hypothalamic leptin signaling in diet-induced obese mice publication-title: Behav. Brain Res. doi: 10.1016/j.bbr.2010.11.022 – volume: 80 start-page: 52 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib136 article-title: Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice publication-title: Pharmacol. Res. doi: 10.1016/j.phrs.2013.12.010 – volume: 4 year: 2007 ident: 10.1016/j.jep.2018.09.004_bib190 article-title: Phytocannabinoids in Cannabis sativa: recent studies on biosynthetic enzymes publication-title: Chem. Biodivers. doi: 10.1002/cbdv.200790145 – volume: 29 start-page: 349 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib93 article-title: Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells publication-title: Oncol. Rep. doi: 10.3892/or.2012.2093 – volume: 24 start-page: 515 year: 2009 ident: 10.1016/j.jep.2018.09.004_bib48 article-title: Cannabis and anxiety: a critical review of the evidence publication-title: Hum. Psychopharmacol. doi: 10.1002/hup.1048 – volume: 109 start-page: 18669 year: 2012 ident: 10.1016/j.jep.2018.09.004_bib66 article-title: Demic and cultural neolithic diffusion publication-title: Proc. Natl. Acad. Sci. doi: 10.1073/pnas.1200662109 – volume: 20 start-page: 461 year: 1995 ident: 10.1016/j.jep.2018.09.004_bib58 article-title: Effects of linalool on glutamatergic system in the rat cerebral cortex publication-title: Neurochem. Res. doi: 10.1007/BF00973103 – volume: 8 start-page: 95 year: 2010 ident: 10.1016/j.jep.2018.09.004_bib59 article-title: A natural approach to soothing atopic skin publication-title: Skinmed – volume: 77 start-page: 1663 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib74 article-title: Identification of endocannabinoid system-modulating N-alkylamides from Heliopsis helianthoides var. scabra and Lepidium meyenii publication-title: J. Nat. Prod. doi: 10.1021/np500292g – volume: 15 start-page: 301 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib113 article-title: A systematic review of the effectiveness of medical cannabis for psychiatric, movement and neurodegenerative disorders publication-title: Clin. Psychopharmacol. Neurosci. doi: 10.9758/cpn.2017.15.4.301 – volume: 7 start-page: 341 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib142 article-title: An orally active cannabis extract with high content in cannabidiol attenuates chemically-induced intestinal inflammation and hypermotility in the mouse publication-title: Front. Pharmacol. doi: 10.3389/fphar.2016.00341 – volume: 36 start-page: 67 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib81 article-title: Systematic review of the costs and benefits of prescribed cannabis-based medicines for the management of chronic illness: lessons from multiple sclerosis publication-title: Pharmacoeconomics doi: 10.1007/s40273-017-0565-6 – ident: 10.1016/j.jep.2018.09.004_bib109 – volume: 28 start-page: 280 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib36 article-title: A cannabigerol-rich Cannabis sativa extract, devoid of [INCREMENT]9-tetrahydrocannabinol, elicits hyperphagia in rats publication-title: Behav. Pharmacol. doi: 10.1097/FBP.0000000000000285 – volume: 43 start-page: 731 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib97 article-title: Alpha-pinene exhibits anti-inflammatory activity through the suppression of MAPKs and the NF-κB pathway in mouse peritoneal macrophages publication-title: Am. J. Chin. Med. doi: 10.1142/S0192415X15500457 – volume: 436 start-page: 423 year: 2001 ident: 10.1016/j.jep.2018.09.004_bib122 article-title: Cannabinoid receptors are absent in insects publication-title: J. Comp. Neurol. doi: 10.1002/cne.1078 – volume: 55 start-page: 63 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib182 article-title: Antinociceptive and anticonvulsant effects of the monoterpene linalool oxide publication-title: Pharm. Biol. doi: 10.1080/13880209.2016.1228682 – volume: 21 start-page: 883 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib203 article-title: Limonene inhibits methamphetamine-induced locomotor activity via regulation of 5-HT neuronal function and dopamine release publication-title: Phytomedicine doi: 10.1016/j.phymed.2013.12.004 – volume: 9 start-page: 733 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib167 article-title: Psychedelic-assisted psychotherapy: a paradigm shift in psychiatric research and development publication-title: Front. Pharmacol. doi: 10.3389/fphar.2018.00733 – year: 1973 ident: 10.1016/j.jep.2018.09.004_bib129 – volume: 63 start-page: 432 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib173 article-title: The effect of cannabichromene on adult neural stem/progenitor cells publication-title: Neurochem. Int. doi: 10.1016/j.neuint.2013.08.002 – volume: 359 start-page: 1 year: 1998 ident: 10.1016/j.jep.2018.09.004_bib126 article-title: Endocannabinoids publication-title: Eur. J. Pharmacol. doi: 10.1016/S0014-2999(98)00649-9 – volume: 61 start-page: 1196 year: 2003 ident: 10.1016/j.jep.2018.09.004_bib192 article-title: Left/right asymmetry of atrophy in semantic dementia: behavioral-cognitive implications publication-title: Neurology doi: 10.1212/01.WNL.0000091868.28557.B8 – volume: 159 start-page: 129 year: 2010 ident: 10.1016/j.jep.2018.09.004_bib42 article-title: Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist publication-title: Br. J. Pharmacol. doi: 10.1111/j.1476-5381.2009.00515.x – volume: 2 start-page: 850 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib140 article-title: In-vitro anti-cholinesterase activity of essential oil from four tropical medicinal plants publication-title: Toxicol. Rep. doi: 10.1016/j.toxrep.2015.05.003 – volume: 90 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib15 article-title: Cannabidiol based medical cannabis in children with autism- a retrospective feasibility study (P3.318) publication-title: Neurology doi: 10.1212/WNL.90.15_supplement.P3.318 – ident: 10.1016/j.jep.2018.09.004_bib200 – volume: 23 start-page: 16012 issue: 2 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib49 article-title: Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids publication-title: NPJ Aging Mech. Dis. doi: 10.1038/npjamd.2016.12 – volume: 31 start-page: 243 issue: 10 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib17 article-title: CB2 cannabinoid receptor as potential target against Alzheimer's disease publication-title: Front. Neurosci. – volume: 81 start-page: 189 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib176 article-title: Evolution and classification of Cannabis sativa (Marijuana, Hemp) in relation to human utilization publication-title: Bot. Rev. doi: 10.1007/s12229-015-9157-3 – volume: 722 start-page: 134 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib172 article-title: Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system publication-title: Eur. J. Pharmacol. doi: 10.1016/j.ejphar.2013.09.068 – year: 2012 ident: 10.1016/j.jep.2018.09.004_bib111 – volume: 134 start-page: 739 year: 2011 ident: 10.1016/j.jep.2018.09.004_bib91 article-title: "Plantas con madre": plants that teach and guide in the shamanic initiation process in the East-Central Peruvian Amazon publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2011.01.042 – volume: 129 start-page: 154 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib64 article-title: Spasticity in patients with multiple sclerosis–clinical characteristics, treatment and quality of life publication-title: Acta Neurol. Scand. doi: 10.1111/ane.12202 – volume: 103 start-page: 712 year: 2008 ident: 10.1016/j.jep.2018.09.004_bib75 article-title: The contribution of research to the development of a national cannabis policy in Australia publication-title: Addiction doi: 10.1111/j.1360-0443.2008.02169.x – volume: 26 start-page: 1541 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib184 article-title: Between China and South Asia: a middle Asian corridor of crop dispersal and agricultural innovation in the bronze age publication-title: Holocene doi: 10.1177/0959683616650268 – start-page: 39 year: 1975 ident: 10.1016/j.jep.2018.09.004_bib25 article-title: Early diffusion and folk uses of hemp – volume: 23 start-page: 337 year: 1974 ident: 10.1016/j.jep.2018.09.004_bib169 article-title: Cannabis: an example of taxonomic neglect publication-title: Bot. Mus. Leafl. Harv. Univ. doi: 10.5962/p.168565 – volume: 8 start-page: 47 year: 1974 ident: 10.1016/j.jep.2018.09.004_bib24 article-title: The effects of marijuana on human sleep patterns publication-title: Biol. Psychiatry – volume: 136 start-page: 168 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib179 article-title: Safety concerns and risk management of multiple sclerosis therapies publication-title: Acta Neurol. Scand. doi: 10.1111/ane.12712 – volume: 5 issue: 2 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib69 article-title: Persons as plants: ecopsychology and the return to the dream of nature publication-title: Landsc.: J. Int. Cent. Landsc. Lang. – volume: 153 start-page: 199 year: 2008 ident: 10.1016/j.jep.2018.09.004_bib149 article-title: The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin publication-title: Br. J. Pharmacol. doi: 10.1038/sj.bjp.0707442 – volume: 110 start-page: 44 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib46 article-title: Cannabis taxonomy: the ‘Sativa’ Vs. ‘Indica’ debate publication-title: HerbalGram – volume: 82 start-page: 1556 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib100 article-title: Systematic review: efficacy and safety of medical marijuana in selected neurologic disorders: report of the Guideline Development Subcommittee of the American Academy of Neurology publication-title: Neurology doi: 10.1212/WNL.0000000000000363 – year: 1980 ident: 10.1016/j.jep.2018.09.004_bib2 – volume: 12 start-page: 2787 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib33 article-title: Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid publication-title: Carcinogenesis doi: 10.1093/carcin/bgu205 – year: 2018 ident: 10.1016/j.jep.2018.09.004_bib62 article-title: The biomedical challenge of neurodegenerative disorders: an opportunity for cannabinoid-based therapies to improve on the poor current therapeutic outcomes publication-title: Br. J. Pharmacol. doi: 10.1111/bph.14382 – volume: 185 start-page: 524 year: 2006 ident: 10.1016/j.jep.2018.09.004_bib197 article-title: Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia publication-title: Psychopharmacology doi: 10.1007/s00213-006-0343-1 – volume: 70 start-page: 777 year: 2011 ident: 10.1016/j.jep.2018.09.004_bib71 article-title: Brain type 1 cannabinoid receptor availability in patients with anorexia and bulimia nervosa publication-title: Biol. Psychiatry doi: 10.1016/j.biopsych.2011.05.010 – volume: 5 start-page: 46 issue: 1 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib54 article-title: Medical use of cannabis. Cannabidiol: a new light for schizophrenia? publication-title: Drug Test. Anal. doi: 10.1002/dta.1425 – volume: 17 start-page: 78 year: 2008 ident: 10.1016/j.jep.2018.09.004_bib60 article-title: An ethno‐methodological approach to Cannabis and music perception, with EEG brain mapping in a naturalistic setting publication-title: Anthropol. Conscious. doi: 10.1525/ac.2006.17.2.78 – volume: 64 start-page: e78 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib8 article-title: Systematic review of systematic reviews for medical cannabinoids: pain, nausea and vomiting, spasticity, and harms publication-title: Can. Fam. Physician – volume: 35 start-page: 847 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib19 article-title: CB2 cannabinoid receptor agonist ameliorates Alzheimer-like phenotype in AβPP/PS1 mice publication-title: J. Alzheimers Dis. doi: 10.3233/JAD-130137 – volume: 19 start-page: 23 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib20 article-title: Cannabis, cannabinoids, and sleep: a review of the literature publication-title: Curr. Psychiatry Rep. doi: 10.1007/s11920-017-0775-9 – volume: 25 start-page: 643 year: 2002 ident: 10.1016/j.jep.2018.09.004_bib23 article-title: Phytol, SSADH inhibitory diterpenoid of Lactuca sativa publication-title: Arch. Pharm. Res. doi: 10.1007/BF02976937 – volume: 2 start-page: 210 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib162 article-title: Cannabis roots: a traditional therapy with future potential for treating inflammation and pain publication-title: Cannabis Cannabinoid Res. doi: 10.1089/can.2017.0028 – volume: 16 start-page: 8057 year: 1996 ident: 10.1016/j.jep.2018.09.004_bib174 article-title: Effects of chronic treatment with delta9-tetrahydrocannabinol on cannabinoid-stimulated [35S]GTPgammaS autoradiography in rat brain publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.16-24-08057.1996 – ident: 10.1016/j.jep.2018.09.004_bib34 – volume: 10 start-page: 1009 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib141 article-title: Effect of non-psychotropic plant-derived cannabinoids on bladder contractility: focus on cannabigerol publication-title: Nat. Prod. Commun. – volume: 80 start-page: 441 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib21 article-title: A review of oral cannabinoids and medical marijuana for the treatment of chemotherapy-induced nausea and vomiting: a focus on pharmacokinetic variability and pharmacodynamics publication-title: Cancer Chemother. Pharmacol. doi: 10.1007/s00280-017-3387-5 – volume: 267 start-page: 4917 year: 2000 ident: 10.1016/j.jep.2018.09.004_bib163 article-title: Comparative biology of the endocannabinoid system possible role in the immune response publication-title: Eur. J. Biochem. doi: 10.1046/j.1432-1327.2000.01550.x – volume: 10 start-page: e0129618 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib166 article-title: Cannabinoid CB2 receptors in a mouse model of Aβ amyloidosis: immunohistochemical analysis and suitability as a PET biomarker of neuroinflammation publication-title: PLoS One doi: 10.1371/journal.pone.0129618 – volume: 22 start-page: E1369 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib195 article-title: Anesthetic agents of plant origin: a review of phytochemicals with anesthetic activity publication-title: Molecules doi: 10.3390/molecules22081369 – volume: 83 start-page: 393 year: 1998 ident: 10.1016/j.jep.2018.09.004_bib194 article-title: Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system publication-title: Neuroscience doi: 10.1016/S0306-4522(97)00436-3 – volume: 139 start-page: 85 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib130 article-title: Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation publication-title: Neuropharmacology doi: 10.1016/j.neuropharm.2018.07.002 – volume: 325 start-page: 1195 year: 2002 ident: 10.1016/j.jep.2018.09.004_bib145 article-title: Cannabis use and mental health in young people: cohort study publication-title: BMJ doi: 10.1136/bmj.325.7374.1195 – volume: 22 start-page: 415 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib201 article-title: Dronabinol for the treatment of agitation and aggressive behavior in acutely hospitalized severely demented patients with noncognitive behavioral symptoms publication-title: Am. J. Geriatr. Psychiatry doi: 10.1016/j.jagp.2012.11.022 – volume: 96 start-page: 5780 year: 1999 ident: 10.1016/j.jep.2018.09.004_bib204 article-title: Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice publication-title: Proc. Natl. Acad. Sci. doi: 10.1073/pnas.96.10.5780 – volume: 9 start-page: 9 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib165 article-title: Plants used in artisanal fisheries on the Western Mediterranean coasts of Italy publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-9-9 – volume: 33 start-page: 138 year: 2012 ident: 10.1016/j.jep.2018.09.004_bib79 article-title: Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro publication-title: Neurotoxicology doi: 10.1016/j.neuro.2011.12.015 – volume: 99 start-page: 80 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib120 article-title: Public perceptions of arguments supporting and opposing recreational marijuana legalization publication-title: Prev. Med. doi: 10.1016/j.ypmed.2017.01.024 – volume: 100 start-page: 259 year: 2011 ident: 10.1016/j.jep.2018.09.004_bib181 article-title: Anxiolytic-like effects of inhaled linalool oxide in experimental mouse anxiety models publication-title: Pharmacol. Biochem. Behav. doi: 10.1016/j.pbb.2011.08.029 – volume: 10 start-page: 26 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib16 article-title: Traditional medicine applied by the Saraguro yachakkuna: a preliminary approach to the use of sacred and psychoactive plant species in the southern region of Ecuador publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-10-26 – volume: 12 start-page: 43 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib37 article-title: A comparative ethnobotany of Khevsureti, Samtskhe-Javakheti, Tusheti, Svaneti, and Racha-Lechkhumi, Republic of Georgia (Sakartvelo), Caucasus publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/s13002-016-0110-2 – volume: 12 start-page: 699 year: 2015 ident: 10.1016/j.jep.2018.09.004_bib87 article-title: Molecular targets of cannabidiol in neurological disorders publication-title: Neurotherapeutics doi: 10.1007/s13311-015-0377-3 – volume: 100 start-page: 328 year: 1990 ident: 10.1016/j.jep.2018.09.004_bib43 article-title: Subjective and behavioral effects of marijuana the morning after smoking publication-title: Psychopharmacology doi: 10.1007/BF02244601 – volume: 9 start-page: 79 year: 1956 ident: 10.1016/j.jep.2018.09.004_bib65 article-title: The old man of the mountain: the growth of a legend publication-title: Symp.: Q. J. Mod. Lit. – volume: 7 start-page: 19 year: 2016 ident: 10.1016/j.jep.2018.09.004_bib11 article-title: Cannabis sativa: the plant of the thousand and one molecules publication-title: Front. Plant Sci. doi: 10.3389/fpls.2016.00019 – volume: 175 start-page: 6 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib85 article-title: Plant glandular trichomes: natural cell factories of high biotechnological interest publication-title: Plant Physiol. doi: 10.1104/pp.17.00727 – volume: 12 start-page: e0173911 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib32 article-title: Terpene synthases from Cannabis sativa publication-title: PLoS One doi: 10.1371/journal.pone.0173911 – volume: 59 start-page: 926 year: 2010 ident: 10.1016/j.jep.2018.09.004_bib95 article-title: CB1 Antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice publication-title: Diabetes doi: 10.2337/db09-1482 – volume: 33 start-page: 14869 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib5 article-title: Endocannabinoids in the brainstem modulate dural trigeminovascular nociceptive traffic via CB1 and “triptan” receptors: implications in migraine publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.0943-13.2013 – volume: 147 start-page: S163 year: 2006 ident: 10.1016/j.jep.2018.09.004_bib148 article-title: Cannabinoid pharmacology: the first 66 years publication-title: Br. J. Pharmacol. doi: 10.1038/sj.bjp.0706406 – volume: 71 start-page: 1427 year: 2008 ident: 10.1016/j.jep.2018.09.004_bib14 article-title: Antibacterial cannabinoids from Cannabis sativa: a structure-activity study publication-title: J. Nat. Prod. doi: 10.1021/np8002673 – volume: 24 start-page: 608 year: 2014 ident: 10.1016/j.jep.2018.09.004_bib98 article-title: The cannabinoid CB 2 receptor‐selective phytocannabinoid beta‐caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain publication-title: Eur. Neuropsychopharmacol. doi: 10.1016/j.euroneuro.2013.10.008 – volume: 62 start-page: 256 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib116 article-title: Novel pyrazole derivatives as neutral CB₁ antagonists with significant activity towards food intake publication-title: Eur. J. Med. Chem. doi: 10.1016/j.ejmech.2012.12.056 – volume: 33 start-page: 402 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib185 article-title: Delta-9-tetrahydrocannabinol (∆(9)-THC) induce neurogenesis and improve cognitive performances of male sprague dawley rats publication-title: Neurotox. Res. doi: 10.1007/s12640-017-9806-x – volume: 30 start-page: 140 year: 2018 ident: 10.1016/j.jep.2018.09.004_bib41 article-title: Psychoactive constituents of cannabis and their clinical implications: a systematic review publication-title: Adicciones doi: 10.20882/adicciones.858 – volume: 1 start-page: 81 year: 2008 ident: 10.1016/j.jep.2018.09.004_bib180 article-title: The chronic effects of cannabis on memory in humans: a review publication-title: Curr. Drug Abus. Rev. doi: 10.2174/1874473710801010081 – volume: 11 start-page: 293 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib99 article-title: Cannabinoid receptor signaling in central regulation of feeding behavior: a mini-review publication-title: Front. Neurosci. doi: 10.3389/fnins.2017.00293 – volume: 7 start-page: 31 year: 2011 ident: 10.1016/j.jep.2018.09.004_bib134 article-title: Ethnobotany of the Monpa ethnic group at Arunachal Pradesh, India publication-title: J. Ethnobiol. Ethnomed. doi: 10.1186/1746-4269-7-31 – volume: 4 start-page: 1614 year: 2007 ident: 10.1016/j.jep.2018.09.004_bib159 article-title: History of cannabis and its preparations in saga, science, and sobriquet publication-title: Chem. Biodivers. doi: 10.1002/cbdv.200790144 – volume: 74 start-page: 94 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib118 article-title: NESS06SM reduces body weight with an improved profile relative to SR141716A publication-title: Pharmacol. Res. doi: 10.1016/j.phrs.2013.06.001 – start-page: 17 year: 2007 ident: 10.1016/j.jep.2018.09.004_bib35 article-title: Chemistry and analysis of phytocannabinoids and other Cannabis constituents doi: 10.1007/978-1-59259-947-9_2 – volume: 18 start-page: E1739 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib90 article-title: Speechlessness in Gilles de la Tourette syndrome: cannabis-based medicines improve severe vocal blocking tics in two patients publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms18081739 – start-page: 3 year: 2017 ident: 10.1016/j.jep.2018.09.004_bib61 article-title: The cannabis plant: botanical aspects – volume: 5 start-page: 363 year: 1843 ident: 10.1016/j.jep.2018.09.004_bib139 article-title: On the preparations of the Indian hemp, or Gunjah publication-title: Prov. Med. J. Retrosp. Med. Sci. – volume: 60 start-page: 2331 year: 2013 ident: 10.1016/j.jep.2018.09.004_bib150 publication-title: Genet. Resour. Crop Evol. doi: 10.1007/s10722-013-0001-5 – volume: 160 start-page: 677 year: 2010 ident: 10.1016/j.jep.2018.09.004_bib29 article-title: The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice publication-title: Br. J. Pharmacol. doi: 10.1111/j.1476-5381.2010.00756.x – start-page: 29 year: 1998 ident: 10.1016/j.jep.2018.09.004_bib151 article-title: The Cannabis plant: botany, cultivation, and processing for use – year: 1974 ident: 10.1016/j.jep.2018.09.004_bib31 – volume: 12 start-page: 254 year: 2012 ident: 10.1016/j.jep.2018.09.004_bib107 article-title: Synthesis and pharmacological evaluation of novel 4-alkyl-5-thien-2'-yl pyrazole carboxamides publication-title: Cent. Nerv. Syst. Agents Med. Chem. doi: 10.2174/187152412803760636 – volume: 25 start-page: 405 year: 1976 ident: 10.1016/j.jep.2018.09.004_bib177 article-title: A practical and natural taxonomy for cannabis publication-title: Taxon doi: 10.2307/1220524 |
| SSID | ssj0007140 |
| Score | 2.682157 |
| SecondaryResourceType | review_article |
| Snippet | Cannabis sativa L. (C. sativa) is an annual dioecious plant, which shares its origins with the inception of the first agricultural human societies in Asia.... |
| SourceID | swepub proquest pubmed crossref elsevier |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 300 |
| SubjectTerms | Animals Asia cannabinoids Cannabis Cannabis sativa Cannabis sativa L colitis dioecy Endocannabinoids Ethnobotany Ethnopharmacology - history food intake glycerol History, 15th Century History, 18th Century History, 19th Century History, 20th Century History, Ancient History, Medieval Humans illicit drugs inflammation inflorescences ligands medicinal plants neurons oils pain phylogeny Phytocannabinoids Phytochemicals - pharmacology plant taxonomy Plants, Medicinal receptors sleep disorders Terpenes - pharmacology Terpenoids therapeutics traditional medicine |
| Title | Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history |
| URI | https://dx.doi.org/10.1016/j.jep.2018.09.004 https://www.ncbi.nlm.nih.gov/pubmed/30205181 https://www.proquest.com/docview/2102920950 https://www.proquest.com/docview/2153617693 http://kipublications.ki.se/Default.aspx?queryparsed=id:139374840 |
| Volume | 227 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3da9swED9K-7KXse4za1c0GHkY9WJH56--hbCSbawU1kLfhOye13TBDk1ayMv-9t1ZcsI-yMMeDLYsgaw7636S7n4H8I5sglZfYxAXOQYYYRrkVWiDJC2yAtkeJyT7HV_Pksklfr6Kr3Zg3MXCiFuln_vdnN7O1r5k4EdzMJ9OB99CoUJng8hKGbGVaSPYMRUt__Bz4-aRuqBIqRxI7e5ks_XxuiWhrIyylurU52r7h236G3v-QSzaGqPTJ_DYo0g1ch3dhx2qn0L_3NFQr47VxSaqanGs-up8Q1C9egY0tnVti-lCiSvPgz1RIyWu5Xd049zZFS1v6ma-aSSSVC7KRTWVssofyXPpfMayUbKdy8Wzpv6uHIXx6jlcnn68GE8Cn24hKHGIy8AOieFAWqaMEsKs4rWKZeuOhAxSbFbqtCJK4qIgzMqQkOTgl3g1iIhUZqnWL2C3bmp6BUrHuSTevLY8D2OV6CKmPMlKviJKdKl7EHYDbUrPRS4pMWamczq7NSwbI7IxYW5YNj14v24yd0Qc2ypjJz3zmzYZNhTbmr3tJG34L5OjE1tTc78wsjDOhwxHw211eEAiyS3Zg5dOTdY91YzKYwZTPeg7vVm_EXpvX_SD78hgFvMi7vX_fcEBPJKn1t8mPoTd5d09vWHUtCyO2t_iCPZGn75Mzn4BNlIVzQ |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3da9swEBclfdhexr6Xrds0GHkYNbGjkz_2FsJKurahsBT6JmT33KYLdmjSQv773Vlywj7Iwx4MRh9g66S730mn3wnxGW0MVl1BoPMMAoggCbIytEGc5GkOZI9j5P2Os0k8voDvl_pyT4zauzAcVul1v9Ppjbb2JX0_mv3FbNb_ETIVOhlEmpQRWRlygfaZnUp3xP7w-GQ82SjkxN2L5PYBd2gPN5swr1tk1soobdhOfbq2f5inv-HnH9yijT06eiqeeCAph-5bn4k9rJ6L3rljol4fyun2YtXyUPbk-Zajev1C4MhWlc1nS8nRPA_2qxxKji6_wxsX0S5xdVPVi20nFqZ0F11kXUor_ak8lS7mJB7JO7pUPK-ra-lYjNcvxcXRt-loHPiMC0EBA1gFdoCECJIiIaAQpiW5K5YMPCAQTrFpoZISMdZ5jpAWIQLy2S-SQwgAWKSJUq9Ep6orfCOk0hnn3ryypIqhjFWuMYvTgp4IY1WorgjbgTaFpyPnrBhz08ad3RqSjWHZmDAzJJuu-LLpsnBcHLsaQys989uEMmQrdnX71Era0ELj0xNbYX2_NOwbZwNCpOGuNjQgEaeX7IrXbppsvlQRMNeEp7qi5-bNpoYZvn3RT3pDA6kmP-7t__3BR_FoPD07NafHk5N34jHXNOE3-kB0Vnf3-J5A1Cr_4BfJL60LGH4 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cannabis+sativa%3A+A+comprehensive+ethnopharmacological+review+of+a+medicinal+plant+with+a+long+history&rft.jtitle=Journal+of+ethnopharmacology&rft.au=Bonini%2C+Sara+Anna&rft.au=Premoli%2C+Marika&rft.au=Tambaro%2C+Simone&rft.au=Kumar%2C+Amit&rft.date=2018-12-05&rft.issn=0378-8741&rft.volume=227&rft.spage=300&rft.epage=315&rft_id=info:doi/10.1016%2Fj.jep.2018.09.004&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_jep_2018_09_004 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0378-8741&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0378-8741&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0378-8741&client=summon |