Bordetella Pertussis Infections in Vaccinated and Unvaccinated Adolescents and Adults, as Assessed in a National Prospective Randomized Acellular Pertussis Vaccine Trial (APERT)

• Published in: Clinical infectious diseases Vol. 43; no. 2; pp. 151 - 157
• Main Authors: Ward, Joel I., Cherry, James D., Chang, Swei-Ju, Partridge, Susan, Keitel, Wendy, Edwards, Kathryn, Lee, Martin, Treanor, John, Greenberg, David P., Barenkamp, Stephen, Bernstein, David I., Edelman, Robert
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 15.07.2006; University of Chicago Press; Oxford University Press
• Subjects: Adolescent; Adolescents; Adult; Aged; Antibodies; Antigens; Bacterial diseases; Biological and medical sciences; Bordetella pertussis; Conflicts of interest; Cough; Disease; Diseases; Double-Blind Method; Ent and stomatologic bacterial diseases; Health; Human bacterial diseases; Humans; Illnesses; Immunization; Immunization, Secondary; Infections; Infectious diseases; Major Articles; Medical sciences; Middle Aged; Pertussis Vaccine - administration & dosage; Prospective Studies; Rates; Sensitivity analysis; Vaccination; Vaccines; Vaccines, Acellular; Whooping cough; Whooping Cough - prevention & control; Human; Infection; Respiratory disease; Adolescent; Bacteriosis; Acellular vaccine; Bacteria; Adult; Bordetella pertussis; Whooping cough
• ISSN: 1058-4838; 1537-6591; 1537-6591
• DOI: 10.1086/504803

Background. Acellular pertussis (aP) booster immunizations have been recommended for adolescents and older persons to enhance long-term protection and to possibly reduce community transmission of infections. Methods. This was a multicenter, randomized, double-blind vaccine trial in which one-half of...