Ferroptosis as an emerging target in inflammatory diseases

• Published in: Progress in biophysics and molecular biology Vol. 155; pp. 20 - 28
• Main Authors: Mao, Huimin, Zhao, Yunhe, Li, Houxuan, Lei, Lang
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2020
• Subjects: Cell death; Ferroptosis; Inflammation; Iron; Lipid peroxidation; Polyunsaturated fatty acids; Lipid peroxidation; Ferroptosis; Inflammation; Iron; Polyunsaturated fatty acids; Cell death

Cell survival or death is one critical issue in inflammatory responses. Ferroptosis, which is characterized by iron-dependent lethal lipid peroxidation, has been found to participate in the development of cancers, degenerative brain diseases and ischemia-reperfusion injuries. Incorporation of polyun...