Next-generation sequencing reveals differentially expressed small noncoding RNAs in uterine leiomyoma

• Published in: Fertility and sterility Vol. 109; no. 5; pp. 919 - 929
• Main Authors: Chuang, Tsai-Der, Xie, Yeming, Yan, Wei, Khorram, Omid
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2018
• Subjects: Adult; AGO2; Female; Gene Expression; High-Throughput Nucleotide Sequencing - methods; High-Throughput Nucleotide Sequencing - trends; Humans; Hysterectomy - trends; leiomyoma; Leiomyoma - genetics; Leiomyoma - metabolism; Leiomyoma - surgery; Middle Aged; piRNA; RNA, Small Untranslated - biosynthesis; RNA, Small Untranslated - genetics; sncRNA; snoRNA; Uterine Neoplasms - genetics; Uterine Neoplasms - metabolism; Uterine Neoplasms - surgery; sncRNA; snoRNA; leiomyoma; piRNA; AGO2

To determine the expression profile of small noncoding RNAs (sncRNAs) in leiomyoma, which has not been investigated to date. Laboratory-based investigation. Academic center. Women undergoing hysterectomy for benign indications. Next-generation sequencing and screening of an sncRNA database with conf...