Next-generation sequencing reveals differentially expressed small noncoding RNAs in uterine leiomyoma
To determine the expression profile of small noncoding RNAs (sncRNAs) in leiomyoma, which has not been investigated to date. Laboratory-based investigation. Academic center. Women undergoing hysterectomy for benign indications. Next-generation sequencing and screening of an sncRNA database with conf...
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Published in | Fertility and sterility Vol. 109; no. 5; pp. 919 - 929 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
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United States
Elsevier Inc
01.05.2018
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Abstract | To determine the expression profile of small noncoding RNAs (sncRNAs) in leiomyoma, which has not been investigated to date.
Laboratory-based investigation.
Academic center.
Women undergoing hysterectomy for benign indications.
Next-generation sequencing and screening of an sncRNA database with confirmatory analysis by quantitative reverse-transcription polymerase chain reaction (qRT-PCR).
Expression profile of sncRNAs in leiomyoma and matched myometrium.
Screening our previously determined RNA sequencing data with the sncRNA database resulted in identification of 15 small nuclear (sn) RNAs, 284 small nucleolar (sno) RNAs, 98 Piwi-interacting (pi) RNAs, 152 transfer (t) RNAs, and 45 ribosomal (r) RNAs, of which 15 snoRNAs, 24 piRNAs, 7 tRNAs, and 6 rRNAs were differentially expressed at a 1.5-fold change cutoff in leiomyoma compared with myometrium. We selected 5 snoRNAs, 4 piRNAs, 1 tRNA, and 1 rRNA that were differentially expressed and confirmed their expression in paired tissues (n = 20) from both phases of the menstrual cycle with the use of qRT-PCR. The results indicated up-regulation of the snoRNAs (SNORD30, SNORD27, SNORA16A, SNORD46, and SNORD56) and down-regulation of the piRNAs (piR-1311, piR-16677, piR-20365, piR-4153), tRNA (TRG-GCC5–1), and rRNA (RNA5SP202) expression in leiomyoma compared with myometrium (P<.05). The pattern of expression of these sncRNAs was similar to RNA sequencing analysis, with no menstrual cycle–dependent differences detected except for SNORD30. Because Argonaute 2 (AGO2) is required for sncRNA-mediated gene silencing, we determined its expression and found greater abundance in leiomyoma.
Our results provide the first evidence for the differential expression of additional classes of sncRNAs and AGO2 in leiomyoma, implicating their roles as a gene regulatory mechanism. |
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AbstractList | To determine the expression profile of small noncoding RNAs (sncRNAs) in leiomyoma, which has not been investigated to date.
Laboratory-based investigation.
Academic center.
Women undergoing hysterectomy for benign indications.
Next-generation sequencing and screening of an sncRNA database with confirmatory analysis by quantitative reverse-transcription polymerase chain reaction (qRT-PCR).
Expression profile of sncRNAs in leiomyoma and matched myometrium.
Screening our previously determined RNA sequencing data with the sncRNA database resulted in identification of 15 small nuclear (sn) RNAs, 284 small nucleolar (sno) RNAs, 98 Piwi-interacting (pi) RNAs, 152 transfer (t) RNAs, and 45 ribosomal (r) RNAs, of which 15 snoRNAs, 24 piRNAs, 7 tRNAs, and 6 rRNAs were differentially expressed at a 1.5-fold change cutoff in leiomyoma compared with myometrium. We selected 5 snoRNAs, 4 piRNAs, 1 tRNA, and 1 rRNA that were differentially expressed and confirmed their expression in paired tissues (n = 20) from both phases of the menstrual cycle with the use of qRT-PCR. The results indicated up-regulation of the snoRNAs (SNORD30, SNORD27, SNORA16A, SNORD46, and SNORD56) and down-regulation of the piRNAs (piR-1311, piR-16677, piR-20365, piR-4153), tRNA (TRG-GCC5-1), and rRNA (RNA5SP202) expression in leiomyoma compared with myometrium (P<.05). The pattern of expression of these sncRNAs was similar to RNA sequencing analysis, with no menstrual cycle-dependent differences detected except for SNORD30. Because Argonaute 2 (AGO2) is required for sncRNA-mediated gene silencing, we determined its expression and found greater abundance in leiomyoma.
Our results provide the first evidence for the differential expression of additional classes of sncRNAs and AGO2 in leiomyoma, implicating their roles as a gene regulatory mechanism. OBJECTIVETo determine the expression profile of small noncoding RNAs (sncRNAs) in leiomyoma, which has not been investigated to date. DESIGNLaboratory-based investigation. SETTINGAcademic center. PATIENT(S)Women undergoing hysterectomy for benign indications. INTERVENTION(S)Next-generation sequencing and screening of an sncRNA database with confirmatory analysis by quantitative reverse-transcription polymerase chain reaction (qRT-PCR). MAIN OUTCOME MEASURE(S)Expression profile of sncRNAs in leiomyoma and matched myometrium. RESULT(S)Screening our previously determined RNA sequencing data with the sncRNA database resulted in identification of 15 small nuclear (sn) RNAs, 284 small nucleolar (sno) RNAs, 98 Piwi-interacting (pi) RNAs, 152 transfer (t) RNAs, and 45 ribosomal (r) RNAs, of which 15 snoRNAs, 24 piRNAs, 7 tRNAs, and 6 rRNAs were differentially expressed at a 1.5-fold change cutoff in leiomyoma compared with myometrium. We selected 5 snoRNAs, 4 piRNAs, 1 tRNA, and 1 rRNA that were differentially expressed and confirmed their expression in paired tissues (n = 20) from both phases of the menstrual cycle with the use of qRT-PCR. The results indicated up-regulation of the snoRNAs (SNORD30, SNORD27, SNORA16A, SNORD46, and SNORD56) and down-regulation of the piRNAs (piR-1311, piR-16677, piR-20365, piR-4153), tRNA (TRG-GCC5-1), and rRNA (RNA5SP202) expression in leiomyoma compared with myometrium (P<.05). The pattern of expression of these sncRNAs was similar to RNA sequencing analysis, with no menstrual cycle-dependent differences detected except for SNORD30. Because Argonaute 2 (AGO2) is required for sncRNA-mediated gene silencing, we determined its expression and found greater abundance in leiomyoma. CONCLUSION(S)Our results provide the first evidence for the differential expression of additional classes of sncRNAs and AGO2 in leiomyoma, implicating their roles as a gene regulatory mechanism. |
Author | Xie, Yeming Chuang, Tsai-Der Yan, Wei Khorram, Omid |
Author_xml | – sequence: 1 givenname: Tsai-Der surname: Chuang fullname: Chuang, Tsai-Der organization: Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center and LA-Biomed Research Institute, Torrance, California – sequence: 2 givenname: Yeming surname: Xie fullname: Xie, Yeming organization: Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, Nevada – sequence: 3 givenname: Wei surname: Yan fullname: Yan, Wei organization: Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, Nevada – sequence: 4 givenname: Omid surname: Khorram fullname: Khorram, Omid email: okhorram@labiomed.org organization: Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center and LA-Biomed Research Institute, Torrance, California |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29778390$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/j.cub.2009.11.064 10.1016/S1071-55760300004-2 10.18632/oncotarget.2349 10.3892/etm.2016.3106 10.1016/j.canlet.2011.03.013 10.1002/ijc.29169 10.1002/gcc.20415 10.1093/humupd/dmt058 10.1371/journal.pone.0166920 10.1177/1933719114553450 10.1186/s13059-014-0550-8 10.1177/1933719117711265 10.1038/sj.bjc.6604653 10.1186/1755-8794-6-27 10.1007/s12094-012-0966-0 10.3892/or.2014.3401 10.18632/oncotarget.2911 10.1073/pnas.1519292113 10.1016/j.cell.2012.02.057 10.1136/gutjnl-2015-309359 10.1055/s-0030-1251476 10.1038/nature21374 10.1093/abbs/gmv018 10.1016/j.molcel.2010.01.032 10.1055/s-0028-1096130 10.1126/science.1118265 10.1038/srep10423 10.1371/journal.pone.0095370 10.1210/me.2012-1075 10.1093/nar/gkr298 10.1126/science.341.6147.732 10.1186/1476-4598-9-198 10.1016/j.ygeno.2012.03.003 10.1016/j.febslet.2014.09.001 10.1038/nrg2814 10.1038/nsmb.1712 10.5808/GI.2015.13.4.94 10.1371/journal.pone.0162622 10.1016/S0955-0674(02)00334-4 10.1016/j.molcel.2008.09.003 10.7314/APJCP.2014.15.18.7553 10.1152/ajpcell.00254.2014 10.1093/nar/gku1291 10.1186/1471-2407-9-426 10.1038/onc.2008.274 10.1186/s12943-016-0491-9 10.3324/haematol.2011.060780 10.1530/ERC-12-0007 10.1155/2015/383056 10.1093/nar/gkm696 10.1073/pnas.1706908114 10.1186/1471-2105-15-29 10.1242/dev.006486 10.1111/j.1742-4658.2010.07632.x 10.1016/j.lfs.2017.08.007 10.1261/rna.1528909 10.1017/S2040174415001208 10.1186/gb4154 10.1074/jbc.M111.286443 10.1038/nrm2321 10.1016/j.fertnstert.2015.09.020 10.1186/1476-4598-13-216 10.1002/bies.201200117 10.1016/j.molcel.2007.05.001 10.3892/mmr.2016.4842 10.1177/1933719116682878 |
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Keywords | sncRNA snoRNA leiomyoma piRNA AGO2 |
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References | Chegini, Verala, Luo, Xu, Williams (bib2) 2003; 10 Busk (bib31) 2014; 15 Anderson, Ivanov (bib19) 2014; 588 Love, Huber, Anders (bib26) 2014; 15 Ravo, Cordella, Rinaldi, Bruno, Alexandrova, Saggese (bib45) 2015; 6 Chuang, Khorram (bib4) 2018; 25 Lopez-Corral, Mateos, Corchete, Sarasquete, de la Rubia, de Arriba (bib34) 2012; 97 Beauchef, Bigot, Kypriotou, Renard, Poree, Widom (bib23) 2012; 287 Klattenhoff, Theurkauf (bib57) 2008; 135 Luo, Chegini (bib11) 2008; 26 Fu, Lee, Lee, Bao (bib18) 2015; 13 He, Wang, Wang, Fan, Shou, Wang (bib62) 2009; 9 Ng, Anderson, Marshall, Minatel, Enfield, Saprunoff (bib17) 2016; 15 Chuang, Khorram (bib12) 2014; 9 Martinez, Vucic, Thu, Hubaux, Enfield, Pikor (bib54) 2015; 5 Balatti, Nigita, Veneziano, Drusco, Stein, Messier (bib68) 2017; 114 Rajasethupathy, Antonov, Sheridan, Frey, Sander, Tuschl (bib55) 2012; 149 Chuang, Khorram (bib33) 2017; 186 Filipowicz, Pogacic (bib49) 2002; 14 Kishore, Stamm (bib50) 2006; 311 Hon, Ramilowski, Harshbarger, Bertin, Rackham, Gough (bib24) 2017; 543 Yan, Hu, Jiang, Maierhofer, Neb, He (bib53) 2011; 39 Tang, Xie, Yan (bib25) 2017 Cao, Xu, Lan, Huang, Tang, Tian (bib61) 2016; 13 Falaleeva, Stamm (bib16) 2013; 35 Mirisola, Mora, Esposito, Guastini, Tabacchiera, Paleari (bib38) 2011; 307 Schickel, Boyerinas, Park, Peter (bib9) 2008; 27 Sloan, Leisegang, Doebele, Ramirez, Simm, Safferthal (bib36) 2015; 43 Liu, Gao, Chen, Xue, Li, Chen (bib65) 2014; 32 Xu, Yang, Ding, Zhao, Ren, Zhao (bib44) 2014; 13 Tan, Liu, Liao, Zhang, Hu, Zou (bib59) 2015; 47 Chuang, Khorram (bib13) 2016; 105 Peters, Meister (bib41) 2007; 26 Huang, Hu, Xue, Shen, Gao, Guo (bib39) 2013; 15 Plestilova, Neidhart, Russo, Frank-Bertoncelj, Ospelt, Ciurea (bib40) 2016; 11 Aravin, Sachidanandam, Bourc’his, Schaefer, Pezic, Toth (bib56) 2008; 31 Falaleeva, Pages, Matuszek, Hidmi, Agranat-Tamir, Korotkov (bib35) 2016; 113 Chuang, Luo, Panda, Chegini (bib14) 2012; 26 Taft, Glazov, Lassmann, Hayashizaki, Carninci, Mattick (bib51) 2009; 15 Okugawa, Toiyama, Toden, Mitoma, Nagasaka, Tanaka (bib48) 2017; 66 Guo, Zhang, Dong, Liu, Li, Lu (bib5) 2014; 5 Le Thomas, Toth, Aravin (bib58) 2014; 15 Wang, Liu, Shen, Zhang, Chen, Yang (bib64) 2012; 5 Kiss, Fayet-Lebaron, Jady (bib8) 2010; 37 Jiang, Tsitsiou, Herrick, Lindsay (bib10) 2010; 277 Ronchetti, Mosca, Cutrona, Tuana, Gentile, Fabris (bib43) 2013; 6 Krishnan, Ghosh, Wang, Heyns, Graham, Mackey (bib37) 2016; 11 Segars, Parrott, Nagel, Guo, Gao, Birnbaum (bib1) 2014; 20 Khorram, Chuang, Pearce (bib32) 2015; 6 Chuang, Panda, Luo, Chegini (bib15) 2012; 19 Robine, Lau, Balla, Jin, Okamura, Kuramochi-Miyagawa (bib52) 2009; 19 Chuang, Pearce, Khorram (bib29) 2015; 309 Alexander, Fang, Rozowsky, Snyder, Gerstein (bib7) 2010; 11 Yang, Bi, Liu, Zhao, Cao, Li (bib67) 2015; 2015 Kupferschmidt (bib21) 2013; 341 Wang, Li, Qi, Chowdhury, Shi, Novina (bib22) 2009; 16 Chegini (bib3) 2010; 28 Sai Lakshmi, Agrawal (bib30) 2008; 36 Chuang, Khorram (bib27) 2017; 24 Wang, Wang, Wang, Song, Zhang (bib60) 2014; 15 Wang, Liu, Wu, Yang (bib66) 2016; 11 Grochola, Greither, Taubert, Moller, Knippschild, Udelnow (bib63) 2008; 99 Wang, Zhang, Obijuru, Laser, Aris, Lee (bib42) 2007; 46 Hutvagner, Simard (bib20) 2008; 9 Chuang, Ho, Khorram (bib28) 2015; 22 Georgieva, Milev, Minkov, Dimitrova, Bradford, Baev (bib6) 2012; 99 Liao, Yu, Mei, Guarnera, Shen, Li (bib46) 2010; 9 Gao, Ma, Mannoor, Guarnera, Shetty, Zhan (bib47) 2015; 136 29778379 - Fertil Steril. 2018 May;109(5):802-803 Chuang (10.1016/j.fertnstert.2018.01.034_bib13) 2016; 105 Kupferschmidt (10.1016/j.fertnstert.2018.01.034_bib21) 2013; 341 Kiss (10.1016/j.fertnstert.2018.01.034_bib8) 2010; 37 Tan (10.1016/j.fertnstert.2018.01.034_bib59) 2015; 47 Khorram (10.1016/j.fertnstert.2018.01.034_bib32) 2015; 6 Ravo (10.1016/j.fertnstert.2018.01.034_bib45) 2015; 6 Rajasethupathy (10.1016/j.fertnstert.2018.01.034_bib55) 2012; 149 Guo (10.1016/j.fertnstert.2018.01.034_bib5) 2014; 5 Peters (10.1016/j.fertnstert.2018.01.034_bib41) 2007; 26 Ng (10.1016/j.fertnstert.2018.01.034_bib17) 2016; 15 Yang (10.1016/j.fertnstert.2018.01.034_bib67) 2015; 2015 Hon (10.1016/j.fertnstert.2018.01.034_bib24) 2017; 543 Kishore (10.1016/j.fertnstert.2018.01.034_bib50) 2006; 311 Lopez-Corral (10.1016/j.fertnstert.2018.01.034_bib34) 2012; 97 Cao (10.1016/j.fertnstert.2018.01.034_bib61) 2016; 13 Love (10.1016/j.fertnstert.2018.01.034_bib26) 2014; 15 Wang (10.1016/j.fertnstert.2018.01.034_bib42) 2007; 46 Robine (10.1016/j.fertnstert.2018.01.034_bib52) 2009; 19 Liao (10.1016/j.fertnstert.2018.01.034_bib46) 2010; 9 Falaleeva (10.1016/j.fertnstert.2018.01.034_bib35) 2016; 113 Chuang (10.1016/j.fertnstert.2018.01.034_bib15) 2012; 19 Huang (10.1016/j.fertnstert.2018.01.034_bib39) 2013; 15 Alexander (10.1016/j.fertnstert.2018.01.034_bib7) 2010; 11 Chuang (10.1016/j.fertnstert.2018.01.034_bib33) 2017; 186 Wang (10.1016/j.fertnstert.2018.01.034_bib60) 2014; 15 Schickel (10.1016/j.fertnstert.2018.01.034_bib9) 2008; 27 Taft (10.1016/j.fertnstert.2018.01.034_bib51) 2009; 15 Chuang (10.1016/j.fertnstert.2018.01.034_bib4) 2018; 25 Wang (10.1016/j.fertnstert.2018.01.034_bib22) 2009; 16 Le Thomas (10.1016/j.fertnstert.2018.01.034_bib58) 2014; 15 Yan (10.1016/j.fertnstert.2018.01.034_bib53) 2011; 39 Wang (10.1016/j.fertnstert.2018.01.034_bib66) 2016; 11 Luo (10.1016/j.fertnstert.2018.01.034_bib11) 2008; 26 Grochola (10.1016/j.fertnstert.2018.01.034_bib63) 2008; 99 Aravin (10.1016/j.fertnstert.2018.01.034_bib56) 2008; 31 Chegini (10.1016/j.fertnstert.2018.01.034_bib2) 2003; 10 Sai Lakshmi (10.1016/j.fertnstert.2018.01.034_bib30) 2008; 36 Fu (10.1016/j.fertnstert.2018.01.034_bib18) 2015; 13 Martinez (10.1016/j.fertnstert.2018.01.034_bib54) 2015; 5 Klattenhoff (10.1016/j.fertnstert.2018.01.034_bib57) 2008; 135 Wang (10.1016/j.fertnstert.2018.01.034_bib64) 2012; 5 Gao (10.1016/j.fertnstert.2018.01.034_bib47) 2015; 136 Jiang (10.1016/j.fertnstert.2018.01.034_bib10) 2010; 277 Ronchetti (10.1016/j.fertnstert.2018.01.034_bib43) 2013; 6 Busk (10.1016/j.fertnstert.2018.01.034_bib31) 2014; 15 Falaleeva (10.1016/j.fertnstert.2018.01.034_bib16) 2013; 35 Hutvagner (10.1016/j.fertnstert.2018.01.034_bib20) 2008; 9 Chuang (10.1016/j.fertnstert.2018.01.034_bib14) 2012; 26 Krishnan (10.1016/j.fertnstert.2018.01.034_bib37) 2016; 11 Georgieva (10.1016/j.fertnstert.2018.01.034_bib6) 2012; 99 Plestilova (10.1016/j.fertnstert.2018.01.034_bib40) 2016; 11 Xu (10.1016/j.fertnstert.2018.01.034_bib44) 2014; 13 Balatti (10.1016/j.fertnstert.2018.01.034_bib68) 2017; 114 Chegini (10.1016/j.fertnstert.2018.01.034_bib3) 2010; 28 Chuang (10.1016/j.fertnstert.2018.01.034_bib28) 2015; 22 Sloan (10.1016/j.fertnstert.2018.01.034_bib36) 2015; 43 Tang (10.1016/j.fertnstert.2018.01.034_bib25) 2017 Okugawa (10.1016/j.fertnstert.2018.01.034_bib48) 2017; 66 Chuang (10.1016/j.fertnstert.2018.01.034_bib27) 2017; 24 Chuang (10.1016/j.fertnstert.2018.01.034_bib29) 2015; 309 Beauchef (10.1016/j.fertnstert.2018.01.034_bib23) 2012; 287 Liu (10.1016/j.fertnstert.2018.01.034_bib65) 2014; 32 Segars (10.1016/j.fertnstert.2018.01.034_bib1) 2014; 20 Anderson (10.1016/j.fertnstert.2018.01.034_bib19) 2014; 588 Mirisola (10.1016/j.fertnstert.2018.01.034_bib38) 2011; 307 Chuang (10.1016/j.fertnstert.2018.01.034_bib12) 2014; 9 Filipowicz (10.1016/j.fertnstert.2018.01.034_bib49) 2002; 14 He (10.1016/j.fertnstert.2018.01.034_bib62) 2009; 9 |
References_xml | – volume: 20 start-page: 309 year: 2014 end-page: 333 ident: bib1 article-title: Proceedings from the Third National Institutes of Health International Congress on Advances in Uterine Leiomyoma Research: comprehensive review, conference summary and future recommendations publication-title: Hum Reprod Update contributor: fullname: Birnbaum – volume: 15 start-page: 5 year: 2016 ident: bib17 article-title: Piwi-interacting RNAs in cancer: emerging functions and clinical utility publication-title: Mol Cancer contributor: fullname: Saprunoff – volume: 15 start-page: 563 year: 2013 end-page: 568 ident: bib39 article-title: Altered expression of piRNAs and their relation with clinicopathologic features of breast cancer publication-title: Cliin Transl Oncol contributor: fullname: Guo – volume: 43 start-page: 553 year: 2015 end-page: 564 ident: bib36 article-title: The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21 publication-title: Nucleic Acids Res contributor: fullname: Safferthal – volume: 11 start-page: 1971 year: 2016 end-page: 1976 ident: bib66 article-title: Manipulations in HIWI level exerts influence on the proliferation of human nonsmall cell lung cancer cells publication-title: Exp Ther Med contributor: fullname: Yang – volume: 309 start-page: C117 year: 2015 end-page: C125 ident: bib29 article-title: miR-29c induction contributes to downregulation of vascular extracellular matrix proteins by glucocorticoids publication-title: Am J Physiol Cell Physiol contributor: fullname: Khorram – volume: 32 start-page: 1853 year: 2014 end-page: 1860 ident: bib65 article-title: Hiwi facilitates chemoresistance as a cancer stem cell marker in cervical cancer publication-title: Oncol Rep contributor: fullname: Chen – volume: 287 start-page: 3462 year: 2012 end-page: 3478 ident: bib23 article-title: The p65 subunit of NF-kappaB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3) publication-title: J Biol Chem contributor: fullname: Widom – volume: 5 start-page: 315 year: 2012 end-page: 325 ident: bib64 article-title: The Piwi protein acts as a predictive marker for human gastric cancer publication-title: Int J Clin Exp Pathol contributor: fullname: Yang – volume: 19 start-page: 541 year: 2012 end-page: 556 ident: bib15 article-title: miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5 publication-title: Endocr Relat Cancer contributor: fullname: Chegini – volume: 135 start-page: 3 year: 2008 end-page: 9 ident: bib57 article-title: Biogenesis and germline functions of piRNAs publication-title: Development (Cambridge, England) contributor: fullname: Theurkauf – volume: 113 start-page: E1625 year: 2016 end-page: E1634 ident: bib35 article-title: Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing publication-title: Proc Natl Acad Sci U S A contributor: fullname: Korotkov – volume: 37 start-page: 597 year: 2010 end-page: 606 ident: bib8 article-title: Box H/ACA small ribonucleoproteins publication-title: Mol Cell contributor: fullname: Jady – volume: 22 start-page: 563 year: 2015 end-page: 571 ident: bib28 article-title: The regulatory function of miR-200c on inflammatory and cell-cycle associated genes in SK-LMS-1, a leiomyosarcoma cell line publication-title: Reprod Sci contributor: fullname: Khorram – volume: 9 start-page: 426 year: 2009 ident: bib62 article-title: Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis publication-title: BMC Cancer contributor: fullname: Wang – volume: 13 start-page: 94 year: 2015 end-page: 101 ident: bib18 article-title: Small noncoding transfer RNA–derived RNA fragments (tRFs): their biogenesis, function and implication in human diseases publication-title: Genomics Inform contributor: fullname: Bao – volume: 15 start-page: 204 year: 2014 ident: bib58 article-title: To be or not to be a piRNA: genomic origin and processing of piRNAs publication-title: Genome Biol contributor: fullname: Aravin – volume: 9 start-page: e95370 year: 2014 ident: bib12 article-title: miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis publication-title: PLoS One contributor: fullname: Khorram – volume: 99 start-page: 1083 year: 2008 end-page: 1088 ident: bib63 article-title: The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death publication-title: Br J Cancer contributor: fullname: Udelnow – start-page: 132928 year: 2017 ident: bib25 article-title: AASRA: An Anchor Alignment-Based Small RNA Annotation Pipeline publication-title: bioRxiv contributor: fullname: Yan – volume: 16 start-page: 1259 year: 2009 end-page: 1266 ident: bib22 article-title: Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins publication-title: Nat Struct Mol Biol contributor: fullname: Novina – volume: 186 start-page: 87 year: 2017 end-page: 91 ident: bib33 article-title: Glucocorticoids regulate MiR-29c levels in vascular smooth muscle cells through transcriptional and epigenetic mechanisms publication-title: Life Sci contributor: fullname: Khorram – volume: 39 start-page: 6596 year: 2011 end-page: 6607 ident: bib53 article-title: Widespread expression of piRNA-like molecules in somatic tissues publication-title: Nucleic Acids Res contributor: fullname: He – volume: 6 start-page: 4677 year: 2015 end-page: 4691 ident: bib45 article-title: Small noncoding RNA deregulation in endometrial carcinogenesis publication-title: Oncotarget contributor: fullname: Saggese – volume: 35 start-page: 46 year: 2013 end-page: 54 ident: bib16 article-title: Processing of snoRNAs as a new source of regulatory noncoding RNAs: snoRNA fragments form a new class of functional RNAs publication-title: Bioessays contributor: fullname: Stamm – volume: 14 start-page: 319 year: 2002 end-page: 327 ident: bib49 article-title: Biogenesis of small nucleolar ribonucleoproteins publication-title: Curr Opin Cell Biol contributor: fullname: Pogacic – volume: 307 start-page: 37 year: 2011 end-page: 46 ident: bib38 article-title: A prognostic multigene classifier for squamous cell carcinomas of the larynx publication-title: Cancer Lett contributor: fullname: Paleari – volume: 15 start-page: 550 year: 2014 ident: bib26 article-title: Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 publication-title: Genome Biol contributor: fullname: Anders – volume: 2015 start-page: 383056 year: 2015 ident: bib67 article-title: Hiwi promotes the proliferation of colorectal cancer cells via upregulating global DNA methylation publication-title: Dis Markers contributor: fullname: Li – volume: 136 start-page: E623 year: 2015 end-page: E629 ident: bib47 article-title: Genome-wide small nucleolar RNA expression analysis of lung cancer by next-generation deep sequencing publication-title: Int J Cancer contributor: fullname: Zhan – volume: 5 start-page: 10423 year: 2015 ident: bib54 article-title: Unique somatic and malignant expression patterns implicate Piwi-interacting RNAs in cancer-type specific biology publication-title: Sci Rep contributor: fullname: Pikor – volume: 66 start-page: 107 year: 2017 end-page: 117 ident: bib48 article-title: Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer publication-title: Gut contributor: fullname: Tanaka – volume: 15 start-page: 7553 year: 2014 end-page: 7558 ident: bib60 article-title: Overexpression of hiwi promotes growth of human breast cancer cells publication-title: Asian Pac J Cancer Prev contributor: fullname: Zhang – volume: 27 start-page: 5959 year: 2008 end-page: 5974 ident: bib9 article-title: MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death publication-title: Oncogene contributor: fullname: Peter – volume: 47 start-page: 315 year: 2015 end-page: 324 ident: bib59 article-title: Emerging roles for Piwi proteins in cancer publication-title: Acta Biochim Biophys Sin (Shanghai) contributor: fullname: Zou – volume: 24 start-page: 1253 year: 2017 end-page: 1263 ident: bib27 article-title: Tranilast inhibits genes functionally involved in cell proliferation, fibrosis, and epigenetic regulation and epigenetically induces miR-29c expression in leiomyoma cells publication-title: Reprod Sci contributor: fullname: Khorram – volume: 149 start-page: 693 year: 2012 end-page: 707 ident: bib55 article-title: A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity publication-title: Cell contributor: fullname: Tuschl – volume: 105 start-page: 236 year: 2016 end-page: 245.e1 ident: bib13 article-title: Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma publication-title: Fertil Steril contributor: fullname: Khorram – volume: 588 start-page: 4297 year: 2014 end-page: 4304 ident: bib19 article-title: tRNA fragments in human health and disease publication-title: FEBS Lett contributor: fullname: Ivanov – volume: 9 start-page: 198 year: 2010 ident: bib46 article-title: Small nucleolar RNA signatures as biomarkers for nonsmall-cell lung cancer publication-title: Mol Cancer contributor: fullname: Li – volume: 6 start-page: 1 year: 2015 end-page: 8 ident: bib32 article-title: Long-term effects of maternal undernutrition on offspring carotid artery remodeling: role of miR-29c publication-title: J Dev Orig Health Dis contributor: fullname: Pearce – volume: 97 start-page: 1439 year: 2012 end-page: 1443 ident: bib34 article-title: Genomic analysis of high-risk smoldering multiple myeloma publication-title: Haematologica contributor: fullname: de Arriba – volume: 6 start-page: 27 year: 2013 ident: bib43 article-title: Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia publication-title: BMC Med Genomics contributor: fullname: Fabris – volume: 28 start-page: 180 year: 2010 end-page: 203 ident: bib3 article-title: Proinflammatory and profibrotic mediators: principal effectors of leiomyoma development as a fibrotic disorder publication-title: Semin Reprod Med contributor: fullname: Chegini – volume: 15 start-page: 29 year: 2014 ident: bib31 article-title: A tool for design of primers for microRNA-specific quantitative RT-qPCR publication-title: BMC Bioinformatics contributor: fullname: Busk – volume: 543 start-page: 199 year: 2017 end-page: 204 ident: bib24 article-title: An atlas of human long noncoding RNAs with accurate 5′ ends publication-title: Nature contributor: fullname: Gough – volume: 99 start-page: 275 year: 2012 end-page: 281 ident: bib6 article-title: Characterization of the uterine leiomyoma microRNAome by deep sequencing publication-title: Genomics contributor: fullname: Baev – volume: 11 start-page: 559 year: 2010 end-page: 571 ident: bib7 article-title: Annotating noncoding regions of the genome publication-title: Nat Rev Genet contributor: fullname: Gerstein – volume: 11 start-page: e0166920 year: 2016 ident: bib40 article-title: Expression and regulation of PiwiL-proteins and Piwi-interacting RNAs in rheumatoid arthritis publication-title: PLoS One contributor: fullname: Ciurea – volume: 46 start-page: 336 year: 2007 end-page: 347 ident: bib42 article-title: A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas publication-title: Genes Chromosomes Cancer contributor: fullname: Lee – volume: 9 start-page: 22 year: 2008 end-page: 32 ident: bib20 article-title: Argonaute proteins: key players in RNA silencing publication-title: Nat Rev Mol Cell Biol contributor: fullname: Simard – volume: 31 start-page: 785 year: 2008 end-page: 799 ident: bib56 article-title: A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice publication-title: Mol Cell contributor: fullname: Toth – volume: 25 start-page: 246 year: 2018 end-page: 255 ident: bib4 article-title: Expression Profiling of lncRNAs, miRNAs, and mRNAs and their differential expression in leiomyoma using next-generation RNA sequencing publication-title: Reprod Sci contributor: fullname: Khorram – volume: 114 start-page: 8071 year: 2017 end-page: 8076 ident: bib68 article-title: tsRNA signatures in cancer publication-title: Proc Natl Acad Sci U S A contributor: fullname: Messier – volume: 5 start-page: 8625 year: 2014 end-page: 8636 ident: bib5 article-title: Integrated analysis of long noncoding RNAs and mRNAs reveals their potential roles in the pathogenesis of uterine leiomyomas publication-title: Oncotarget contributor: fullname: Lu – volume: 19 start-page: 2066 year: 2009 end-page: 2076 ident: bib52 article-title: A broadly conserved pathway generates 3′UTR-directed primary piRNAs publication-title: Curr Biol contributor: fullname: Kuramochi-Miyagawa – volume: 26 start-page: 1028 year: 2012 end-page: 1042 ident: bib14 article-title: miR-93/106b and their host gene, MCM7, are differentially expressed in leiomyomas and functionally target F3 and IL-8 publication-title: Mol Endocrinol contributor: fullname: Chegini – volume: 311 start-page: 230 year: 2006 end-page: 232 ident: bib50 article-title: The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C publication-title: Science contributor: fullname: Stamm – volume: 36 start-page: D173 year: 2008 end-page: D177 ident: bib30 article-title: piRNABank: a web resource on classified and clustered Piwi-interacting RNAs publication-title: Nucleic Acids Res contributor: fullname: Agrawal – volume: 11 start-page: e0162622 year: 2016 ident: bib37 article-title: Profiling of small nucleolar RNAs by next generation sequencing: potential new players for breast cancer prognosis publication-title: PLoS One contributor: fullname: Mackey – volume: 13 start-page: 216 year: 2014 ident: bib44 article-title: Small nucleolar RNA 113-1 suppresses tumorigenesis in hepatocellular carcinoma publication-title: Mol Cancer contributor: fullname: Zhao – volume: 277 start-page: 2015 year: 2010 end-page: 2021 ident: bib10 article-title: MicroRNAs and the regulation of fibrosis publication-title: FEBS J contributor: fullname: Lindsay – volume: 15 start-page: 1233 year: 2009 end-page: 1240 ident: bib51 article-title: Small RNAs derived from snoRNAs publication-title: RNA contributor: fullname: Mattick – volume: 10 start-page: 161 year: 2003 end-page: 171 ident: bib2 article-title: Gene expression profile of leiomyoma and myometrium and the effect of gonadotropin releasing hormone analogue therapy publication-title: J Soc Gynecol Invest contributor: fullname: Williams – volume: 341 start-page: 732 year: 2013 end-page: 733 ident: bib21 article-title: A lethal dose of RNA publication-title: Science contributor: fullname: Kupferschmidt – volume: 26 start-page: 611 year: 2007 end-page: 623 ident: bib41 article-title: Argonaute proteins: mediators of RNA silencing publication-title: Mol Cell contributor: fullname: Meister – volume: 26 start-page: 500 year: 2008 end-page: 514 ident: bib11 article-title: The expression and potential regulatory function of microRNAs in the pathogenesis of leiomyoma publication-title: Semin Reprod Med contributor: fullname: Chegini – volume: 13 start-page: 2829 year: 2016 end-page: 2835 ident: bib61 article-title: High expression of Piwi-like RNA-mediated gene silencing 1 is associated with poor prognosis via regulating transforming growth factor-beta receptors and cyclin-dependent kinases in breast cancer publication-title: Mol Med Rep contributor: fullname: Tian – volume: 19 start-page: 2066 year: 2009 ident: 10.1016/j.fertnstert.2018.01.034_bib52 article-title: A broadly conserved pathway generates 3′UTR-directed primary piRNAs publication-title: Curr Biol doi: 10.1016/j.cub.2009.11.064 contributor: fullname: Robine – volume: 10 start-page: 161 year: 2003 ident: 10.1016/j.fertnstert.2018.01.034_bib2 article-title: Gene expression profile of leiomyoma and myometrium and the effect of gonadotropin releasing hormone analogue therapy publication-title: J Soc Gynecol Invest doi: 10.1016/S1071-55760300004-2 contributor: fullname: Chegini – volume: 5 start-page: 8625 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib5 article-title: Integrated analysis of long noncoding RNAs and mRNAs reveals their potential roles in the pathogenesis of uterine leiomyomas publication-title: Oncotarget doi: 10.18632/oncotarget.2349 contributor: fullname: Guo – volume: 11 start-page: 1971 year: 2016 ident: 10.1016/j.fertnstert.2018.01.034_bib66 article-title: Manipulations in HIWI level exerts influence on the proliferation of human nonsmall cell lung cancer cells publication-title: Exp Ther Med doi: 10.3892/etm.2016.3106 contributor: fullname: Wang – volume: 307 start-page: 37 year: 2011 ident: 10.1016/j.fertnstert.2018.01.034_bib38 article-title: A prognostic multigene classifier for squamous cell carcinomas of the larynx publication-title: Cancer Lett doi: 10.1016/j.canlet.2011.03.013 contributor: fullname: Mirisola – volume: 136 start-page: E623 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib47 article-title: Genome-wide small nucleolar RNA expression analysis of lung cancer by next-generation deep sequencing publication-title: Int J Cancer doi: 10.1002/ijc.29169 contributor: fullname: Gao – volume: 46 start-page: 336 year: 2007 ident: 10.1016/j.fertnstert.2018.01.034_bib42 article-title: A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas publication-title: Genes Chromosomes Cancer doi: 10.1002/gcc.20415 contributor: fullname: Wang – volume: 20 start-page: 309 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib1 article-title: Proceedings from the Third National Institutes of Health International Congress on Advances in Uterine Leiomyoma Research: comprehensive review, conference summary and future recommendations publication-title: Hum Reprod Update doi: 10.1093/humupd/dmt058 contributor: fullname: Segars – volume: 11 start-page: e0166920 year: 2016 ident: 10.1016/j.fertnstert.2018.01.034_bib40 article-title: Expression and regulation of PiwiL-proteins and Piwi-interacting RNAs in rheumatoid arthritis publication-title: PLoS One doi: 10.1371/journal.pone.0166920 contributor: fullname: Plestilova – volume: 22 start-page: 563 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib28 article-title: The regulatory function of miR-200c on inflammatory and cell-cycle associated genes in SK-LMS-1, a leiomyosarcoma cell line publication-title: Reprod Sci doi: 10.1177/1933719114553450 contributor: fullname: Chuang – volume: 15 start-page: 550 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib26 article-title: Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 publication-title: Genome Biol doi: 10.1186/s13059-014-0550-8 contributor: fullname: Love – volume: 25 start-page: 246 year: 2018 ident: 10.1016/j.fertnstert.2018.01.034_bib4 article-title: Expression Profiling of lncRNAs, miRNAs, and mRNAs and their differential expression in leiomyoma using next-generation RNA sequencing publication-title: Reprod Sci doi: 10.1177/1933719117711265 contributor: fullname: Chuang – volume: 99 start-page: 1083 year: 2008 ident: 10.1016/j.fertnstert.2018.01.034_bib63 article-title: The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death publication-title: Br J Cancer doi: 10.1038/sj.bjc.6604653 contributor: fullname: Grochola – volume: 6 start-page: 27 year: 2013 ident: 10.1016/j.fertnstert.2018.01.034_bib43 article-title: Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia publication-title: BMC Med Genomics doi: 10.1186/1755-8794-6-27 contributor: fullname: Ronchetti – volume: 15 start-page: 563 year: 2013 ident: 10.1016/j.fertnstert.2018.01.034_bib39 article-title: Altered expression of piRNAs and their relation with clinicopathologic features of breast cancer publication-title: Cliin Transl Oncol doi: 10.1007/s12094-012-0966-0 contributor: fullname: Huang – volume: 32 start-page: 1853 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib65 article-title: Hiwi facilitates chemoresistance as a cancer stem cell marker in cervical cancer publication-title: Oncol Rep doi: 10.3892/or.2014.3401 contributor: fullname: Liu – volume: 6 start-page: 4677 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib45 article-title: Small noncoding RNA deregulation in endometrial carcinogenesis publication-title: Oncotarget doi: 10.18632/oncotarget.2911 contributor: fullname: Ravo – volume: 113 start-page: E1625 year: 2016 ident: 10.1016/j.fertnstert.2018.01.034_bib35 article-title: Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1519292113 contributor: fullname: Falaleeva – volume: 149 start-page: 693 year: 2012 ident: 10.1016/j.fertnstert.2018.01.034_bib55 article-title: A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity publication-title: Cell doi: 10.1016/j.cell.2012.02.057 contributor: fullname: Rajasethupathy – volume: 66 start-page: 107 year: 2017 ident: 10.1016/j.fertnstert.2018.01.034_bib48 article-title: Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer publication-title: Gut doi: 10.1136/gutjnl-2015-309359 contributor: fullname: Okugawa – volume: 28 start-page: 180 year: 2010 ident: 10.1016/j.fertnstert.2018.01.034_bib3 article-title: Proinflammatory and profibrotic mediators: principal effectors of leiomyoma development as a fibrotic disorder publication-title: Semin Reprod Med doi: 10.1055/s-0030-1251476 contributor: fullname: Chegini – volume: 543 start-page: 199 year: 2017 ident: 10.1016/j.fertnstert.2018.01.034_bib24 article-title: An atlas of human long noncoding RNAs with accurate 5′ ends publication-title: Nature doi: 10.1038/nature21374 contributor: fullname: Hon – volume: 47 start-page: 315 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib59 article-title: Emerging roles for Piwi proteins in cancer publication-title: Acta Biochim Biophys Sin (Shanghai) doi: 10.1093/abbs/gmv018 contributor: fullname: Tan – volume: 37 start-page: 597 year: 2010 ident: 10.1016/j.fertnstert.2018.01.034_bib8 article-title: Box H/ACA small ribonucleoproteins publication-title: Mol Cell doi: 10.1016/j.molcel.2010.01.032 contributor: fullname: Kiss – volume: 26 start-page: 500 year: 2008 ident: 10.1016/j.fertnstert.2018.01.034_bib11 article-title: The expression and potential regulatory function of microRNAs in the pathogenesis of leiomyoma publication-title: Semin Reprod Med doi: 10.1055/s-0028-1096130 contributor: fullname: Luo – volume: 311 start-page: 230 year: 2006 ident: 10.1016/j.fertnstert.2018.01.034_bib50 article-title: The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C publication-title: Science doi: 10.1126/science.1118265 contributor: fullname: Kishore – volume: 5 start-page: 10423 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib54 article-title: Unique somatic and malignant expression patterns implicate Piwi-interacting RNAs in cancer-type specific biology publication-title: Sci Rep doi: 10.1038/srep10423 contributor: fullname: Martinez – volume: 9 start-page: e95370 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib12 article-title: miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis publication-title: PLoS One doi: 10.1371/journal.pone.0095370 contributor: fullname: Chuang – volume: 26 start-page: 1028 year: 2012 ident: 10.1016/j.fertnstert.2018.01.034_bib14 article-title: miR-93/106b and their host gene, MCM7, are differentially expressed in leiomyomas and functionally target F3 and IL-8 publication-title: Mol Endocrinol doi: 10.1210/me.2012-1075 contributor: fullname: Chuang – volume: 5 start-page: 315 year: 2012 ident: 10.1016/j.fertnstert.2018.01.034_bib64 article-title: The Piwi protein acts as a predictive marker for human gastric cancer publication-title: Int J Clin Exp Pathol contributor: fullname: Wang – volume: 39 start-page: 6596 year: 2011 ident: 10.1016/j.fertnstert.2018.01.034_bib53 article-title: Widespread expression of piRNA-like molecules in somatic tissues publication-title: Nucleic Acids Res doi: 10.1093/nar/gkr298 contributor: fullname: Yan – volume: 341 start-page: 732 year: 2013 ident: 10.1016/j.fertnstert.2018.01.034_bib21 article-title: A lethal dose of RNA publication-title: Science doi: 10.1126/science.341.6147.732 contributor: fullname: Kupferschmidt – volume: 9 start-page: 198 year: 2010 ident: 10.1016/j.fertnstert.2018.01.034_bib46 article-title: Small nucleolar RNA signatures as biomarkers for nonsmall-cell lung cancer publication-title: Mol Cancer doi: 10.1186/1476-4598-9-198 contributor: fullname: Liao – volume: 99 start-page: 275 year: 2012 ident: 10.1016/j.fertnstert.2018.01.034_bib6 article-title: Characterization of the uterine leiomyoma microRNAome by deep sequencing publication-title: Genomics doi: 10.1016/j.ygeno.2012.03.003 contributor: fullname: Georgieva – volume: 588 start-page: 4297 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib19 article-title: tRNA fragments in human health and disease publication-title: FEBS Lett doi: 10.1016/j.febslet.2014.09.001 contributor: fullname: Anderson – volume: 11 start-page: 559 year: 2010 ident: 10.1016/j.fertnstert.2018.01.034_bib7 article-title: Annotating noncoding regions of the genome publication-title: Nat Rev Genet doi: 10.1038/nrg2814 contributor: fullname: Alexander – volume: 16 start-page: 1259 year: 2009 ident: 10.1016/j.fertnstert.2018.01.034_bib22 article-title: Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins publication-title: Nat Struct Mol Biol doi: 10.1038/nsmb.1712 contributor: fullname: Wang – volume: 13 start-page: 94 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib18 article-title: Small noncoding transfer RNA–derived RNA fragments (tRFs): their biogenesis, function and implication in human diseases publication-title: Genomics Inform doi: 10.5808/GI.2015.13.4.94 contributor: fullname: Fu – volume: 11 start-page: e0162622 year: 2016 ident: 10.1016/j.fertnstert.2018.01.034_bib37 article-title: Profiling of small nucleolar RNAs by next generation sequencing: potential new players for breast cancer prognosis publication-title: PLoS One doi: 10.1371/journal.pone.0162622 contributor: fullname: Krishnan – volume: 14 start-page: 319 year: 2002 ident: 10.1016/j.fertnstert.2018.01.034_bib49 article-title: Biogenesis of small nucleolar ribonucleoproteins publication-title: Curr Opin Cell Biol doi: 10.1016/S0955-0674(02)00334-4 contributor: fullname: Filipowicz – volume: 31 start-page: 785 year: 2008 ident: 10.1016/j.fertnstert.2018.01.034_bib56 article-title: A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice publication-title: Mol Cell doi: 10.1016/j.molcel.2008.09.003 contributor: fullname: Aravin – volume: 15 start-page: 7553 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib60 article-title: Overexpression of hiwi promotes growth of human breast cancer cells publication-title: Asian Pac J Cancer Prev doi: 10.7314/APJCP.2014.15.18.7553 contributor: fullname: Wang – volume: 309 start-page: C117 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib29 article-title: miR-29c induction contributes to downregulation of vascular extracellular matrix proteins by glucocorticoids publication-title: Am J Physiol Cell Physiol doi: 10.1152/ajpcell.00254.2014 contributor: fullname: Chuang – start-page: 132928 year: 2017 ident: 10.1016/j.fertnstert.2018.01.034_bib25 article-title: AASRA: An Anchor Alignment-Based Small RNA Annotation Pipeline publication-title: bioRxiv contributor: fullname: Tang – volume: 43 start-page: 553 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib36 article-title: The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21 publication-title: Nucleic Acids Res doi: 10.1093/nar/gku1291 contributor: fullname: Sloan – volume: 9 start-page: 426 year: 2009 ident: 10.1016/j.fertnstert.2018.01.034_bib62 article-title: Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis publication-title: BMC Cancer doi: 10.1186/1471-2407-9-426 contributor: fullname: He – volume: 27 start-page: 5959 year: 2008 ident: 10.1016/j.fertnstert.2018.01.034_bib9 article-title: MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death publication-title: Oncogene doi: 10.1038/onc.2008.274 contributor: fullname: Schickel – volume: 15 start-page: 5 year: 2016 ident: 10.1016/j.fertnstert.2018.01.034_bib17 article-title: Piwi-interacting RNAs in cancer: emerging functions and clinical utility publication-title: Mol Cancer doi: 10.1186/s12943-016-0491-9 contributor: fullname: Ng – volume: 97 start-page: 1439 year: 2012 ident: 10.1016/j.fertnstert.2018.01.034_bib34 article-title: Genomic analysis of high-risk smoldering multiple myeloma publication-title: Haematologica doi: 10.3324/haematol.2011.060780 contributor: fullname: Lopez-Corral – volume: 19 start-page: 541 year: 2012 ident: 10.1016/j.fertnstert.2018.01.034_bib15 article-title: miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5 publication-title: Endocr Relat Cancer doi: 10.1530/ERC-12-0007 contributor: fullname: Chuang – volume: 2015 start-page: 383056 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib67 article-title: Hiwi promotes the proliferation of colorectal cancer cells via upregulating global DNA methylation publication-title: Dis Markers doi: 10.1155/2015/383056 contributor: fullname: Yang – volume: 36 start-page: D173 year: 2008 ident: 10.1016/j.fertnstert.2018.01.034_bib30 article-title: piRNABank: a web resource on classified and clustered Piwi-interacting RNAs publication-title: Nucleic Acids Res doi: 10.1093/nar/gkm696 contributor: fullname: Sai Lakshmi – volume: 114 start-page: 8071 year: 2017 ident: 10.1016/j.fertnstert.2018.01.034_bib68 article-title: tsRNA signatures in cancer publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1706908114 contributor: fullname: Balatti – volume: 15 start-page: 29 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib31 article-title: A tool for design of primers for microRNA-specific quantitative RT-qPCR publication-title: BMC Bioinformatics doi: 10.1186/1471-2105-15-29 contributor: fullname: Busk – volume: 135 start-page: 3 year: 2008 ident: 10.1016/j.fertnstert.2018.01.034_bib57 article-title: Biogenesis and germline functions of piRNAs publication-title: Development (Cambridge, England) doi: 10.1242/dev.006486 contributor: fullname: Klattenhoff – volume: 277 start-page: 2015 year: 2010 ident: 10.1016/j.fertnstert.2018.01.034_bib10 article-title: MicroRNAs and the regulation of fibrosis publication-title: FEBS J doi: 10.1111/j.1742-4658.2010.07632.x contributor: fullname: Jiang – volume: 186 start-page: 87 year: 2017 ident: 10.1016/j.fertnstert.2018.01.034_bib33 article-title: Glucocorticoids regulate MiR-29c levels in vascular smooth muscle cells through transcriptional and epigenetic mechanisms publication-title: Life Sci doi: 10.1016/j.lfs.2017.08.007 contributor: fullname: Chuang – volume: 15 start-page: 1233 year: 2009 ident: 10.1016/j.fertnstert.2018.01.034_bib51 article-title: Small RNAs derived from snoRNAs publication-title: RNA doi: 10.1261/rna.1528909 contributor: fullname: Taft – volume: 6 start-page: 1 year: 2015 ident: 10.1016/j.fertnstert.2018.01.034_bib32 article-title: Long-term effects of maternal undernutrition on offspring carotid artery remodeling: role of miR-29c publication-title: J Dev Orig Health Dis doi: 10.1017/S2040174415001208 contributor: fullname: Khorram – volume: 15 start-page: 204 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib58 article-title: To be or not to be a piRNA: genomic origin and processing of piRNAs publication-title: Genome Biol doi: 10.1186/gb4154 contributor: fullname: Le Thomas – volume: 287 start-page: 3462 year: 2012 ident: 10.1016/j.fertnstert.2018.01.034_bib23 article-title: The p65 subunit of NF-kappaB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3) publication-title: J Biol Chem doi: 10.1074/jbc.M111.286443 contributor: fullname: Beauchef – volume: 9 start-page: 22 year: 2008 ident: 10.1016/j.fertnstert.2018.01.034_bib20 article-title: Argonaute proteins: key players in RNA silencing publication-title: Nat Rev Mol Cell Biol doi: 10.1038/nrm2321 contributor: fullname: Hutvagner – volume: 105 start-page: 236 year: 2016 ident: 10.1016/j.fertnstert.2018.01.034_bib13 article-title: Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma publication-title: Fertil Steril doi: 10.1016/j.fertnstert.2015.09.020 contributor: fullname: Chuang – volume: 13 start-page: 216 year: 2014 ident: 10.1016/j.fertnstert.2018.01.034_bib44 article-title: Small nucleolar RNA 113-1 suppresses tumorigenesis in hepatocellular carcinoma publication-title: Mol Cancer doi: 10.1186/1476-4598-13-216 contributor: fullname: Xu – volume: 35 start-page: 46 year: 2013 ident: 10.1016/j.fertnstert.2018.01.034_bib16 article-title: Processing of snoRNAs as a new source of regulatory noncoding RNAs: snoRNA fragments form a new class of functional RNAs publication-title: Bioessays doi: 10.1002/bies.201200117 contributor: fullname: Falaleeva – volume: 26 start-page: 611 year: 2007 ident: 10.1016/j.fertnstert.2018.01.034_bib41 article-title: Argonaute proteins: mediators of RNA silencing publication-title: Mol Cell doi: 10.1016/j.molcel.2007.05.001 contributor: fullname: Peters – volume: 13 start-page: 2829 year: 2016 ident: 10.1016/j.fertnstert.2018.01.034_bib61 article-title: High expression of Piwi-like RNA-mediated gene silencing 1 is associated with poor prognosis via regulating transforming growth factor-beta receptors and cyclin-dependent kinases in breast cancer publication-title: Mol Med Rep doi: 10.3892/mmr.2016.4842 contributor: fullname: Cao – volume: 24 start-page: 1253 year: 2017 ident: 10.1016/j.fertnstert.2018.01.034_bib27 article-title: Tranilast inhibits genes functionally involved in cell proliferation, fibrosis, and epigenetic regulation and epigenetically induces miR-29c expression in leiomyoma cells publication-title: Reprod Sci doi: 10.1177/1933719116682878 contributor: fullname: Chuang |
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Snippet | To determine the expression profile of small noncoding RNAs (sncRNAs) in leiomyoma, which has not been investigated to date.
Laboratory-based investigation.... OBJECTIVETo determine the expression profile of small noncoding RNAs (sncRNAs) in leiomyoma, which has not been investigated to date. DESIGNLaboratory-based... |
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SubjectTerms | Adult AGO2 Female Gene Expression High-Throughput Nucleotide Sequencing - methods High-Throughput Nucleotide Sequencing - trends Humans Hysterectomy - trends leiomyoma Leiomyoma - genetics Leiomyoma - metabolism Leiomyoma - surgery Middle Aged piRNA RNA, Small Untranslated - biosynthesis RNA, Small Untranslated - genetics sncRNA snoRNA Uterine Neoplasms - genetics Uterine Neoplasms - metabolism Uterine Neoplasms - surgery |
Title | Next-generation sequencing reveals differentially expressed small noncoding RNAs in uterine leiomyoma |
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