Accurate characterization of dynamic microbial gene expression and growth rate profiles

• Published in: Synthetic biology (Oxford University Press) Vol. 7; no. 1; p. ysac020
• Main Authors: Vidal, Gonzalo, Vidal-Céspedes, Carlos, Muñoz Silva, Macarena, Castillo-Passi, Carlos, Yáñez Feliú, Guillermo, Federici, Fernán, Rudge, Timothy J
• Format: Journal Article
• Language: English
• Published: UK Oxford University Press 2022
• Subjects: dynamical systems; web application; characterization; gene expression; Inverse problem

Abstract Genetic circuits are subject to variability due to cellular and compositional contexts. Cells face changing internal states and environments, the cellular context, to which they sense and respond by changing their gene expression and growth rates. Furthermore, each gene in a genetic circuit...