Detection of human bocavirus in nasopharyngeal aspirates versus in broncho-alveolar lavage fluids in children with lower respiratory tract infections

• Published in: Journal of medical virology Vol. 88; no. 2; pp. 211 - 215
• Main Authors: Li, Ling, Zhu, Tian, Chen, Zheng-Rong, Yan, Yong-Dong, He, Li-Ping, Xu, Hong-Mei, Shao, Xue-Jun, Yin, Fang, Ji, Wei
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.02.2016; Wiley Subscription Services, Inc
• Subjects: Adolescent; Bodily Secretions - virology; broncho-alveolar lavage fluids; Bronchoalveolar Lavage Fluid - virology; Child; Child, Preschool; children; Children & youth; Female; human bocavirus; Human bocavirus - isolation & purification; Humans; Infant; Infant, Newborn; Male; Medical diagnosis; nasopharyngeal aspirates; Nasopharynx - virology; Parvoviridae Infections - diagnosis; Parvoviridae Infections - virology; Real-Time Polymerase Chain Reaction - methods; Respiratory Tract Infections - diagnosis; Respiratory Tract Infections - virology; Retrospective Studies; Specimen Handling - methods; Virology; nasopharyngeal aspirates; broncho-alveolar lavage fluids; children; human bocavirus

To compare the presence of human bocavirus (HBoV) in nasopharyngeal aspirates (NPA) versus broncho‐alveolar lavage fluids (BAL) in children with lower respiratory tract infections (LRTIs), as revealed by real‐time PCR, in order to confirm the diagnostic validity of NPA samples. A retrospective 5‐yea...