Origin of the dopaminergic innervation of adult neurogenic areas

• Published in: Journal of comparative neurology (1911) Vol. 522; no. 10; pp. 2336 - 2348
• Main Authors: Höglinger, Günter U., Arias-Carrión, Oscar, Ipach, Bastian, Oertel, Wolfgang H.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.07.2014; Wiley Subscription Services, Inc
• Subjects: adult neurogenesis; Animals; Bromodeoxyuridine; Dopaminergic Neurons - cytology; Fluorescent Antibody Technique; Green Fluorescent Proteins - genetics; Hippocampus - anatomy & histology; Lateral Ventricles - anatomy & histology; Male; Mice, Transgenic; Neural Pathways - anatomy & histology; Neural Stem Cells - cytology; Neuroanatomical Tract-Tracing Techniques; Neurogenesis; Pars Compacta - anatomy & histology; Primates; Rats, Wistar; retrorubral field; subgranular zone; substantia nigra; subventricular zone; Ventral Tegmental Area - anatomy & histology; ventrotegmental area; adult neurogenesis; subventricular zone; subgranular zone; substantia nigra; retrorubral field; ventrotegmental area

ABSTRACT Adult neurogenesis, a specific form of brain plasticity in mammals occurring in the subventricular zone (SVZ) and the subgranular zone (SGZ), is subject to complex regulations. Dopamine has been identified as a regulatory factor in rodents, nonhuman primates, and humans. We therefore studie...