Impact of age and gender on the pharmacokinetics of gemtuzumab ozogamicin

• Published in: Pharmacotherapy Vol. 21; no. 10; p. 1175
• Main Authors: Korth-Bradley, J M, Dowell, J A, King, S P, Liu, H, Berger, M S
• Format: Journal Article
• Language: English
• Published: United States 01.10.2001
• Subjects: Adult; Aged; Aged, 80 and over; Aging - physiology; Aminoglycosides; Anti-Bacterial Agents - pharmacokinetics; Antibodies, Monoclonal - pharmacokinetics; Antibodies, Monoclonal, Humanized; Area Under Curve; Female; Half-Life; Humans; Male; Middle Aged; Sex Characteristics

To determine the pharmacokinetic parameters of the components of gemtuzumab ozogamicin and to assess the possible influence of age and gender on the values. Phase II, multicenter, open-label, nonrandomized, parallel study Hospitals and outpatient oncology clinics. Fifty-eight patients with acute mye...