Biochemical investigation and gene expression analysis of the immunostimulatory functions of an edible Salacia extract in rat small intestine

• Published in: BioFactors (Oxford) Vol. 37; no. 1; pp. 31 - 39
• Main Authors: Oda, Yuriko, Ueda, Fumitaka, Kamei, Asuka, Kakinuma, Chihaya, Abe, Keiko
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.01.2011
• Subjects: Adjuvants, Immunologic - pharmacology; Animals; Bacteria - isolation & purification; Cluster Analysis; DNA microarray; Down-Regulation; Feces - microbiology; Gene Expression Profiling; Ileum - drug effects; Ileum - immunology; Ileum - microbiology; intestinal bacterial flora; intestinal immunity; Intestinal Mucosa - drug effects; Intestinal Mucosa - immunology; Intestinal Mucosa - microbiology; Male; Organ Size - drug effects; Plant Bark - chemistry; Plant Extracts - pharmacology; Plant Roots - chemistry; Rats; Rats, Sprague-Dawley; Salacia; Salacia - chemistry; Up-Regulation

Roots and bark from plants belonging to genus Salacia of the family Hippocrateaceae (Salacia reticulata, Salacia oblonga, etc.) have been used for traditional Ayurvedic medicine, particularly for the treatment of diabetes. In our study, we evaluated the gene expression profiles in the small intestin...