Abstract This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on caregivers and society. The Special Report examines the benefits of diagnosing Alzheimer's earlier in the disease process, in the stage of mild cognitive impairment due to Alzheimer's disease. An estimated 5.7 million Americans have Alzheimer's dementia. By mid-century, the number of people living with Alzheimer's dementia in the United States is projected to grow to 13.8 million, fueled in large part by the aging baby boom generation. In 2015, official death certificates recorded 110,561 deaths from AD, making AD the sixth leading cause of death in the United States and the fifth leading cause of death in Americans age ≥65 years. Between 2000 and 2015, deaths resulting from stroke, heart disease, and prostate cancer decreased, whereas deaths from AD increased 123%. In 2017, more than 16 million family members and other unpaid caregivers provided an estimated 18.4 billion hours of care to people with Alzheimer's or other dementias. This care is valued at more than $232 billion, but its costs extend to family caregivers' increased risk for emotional distress and negative mental and physical health outcomes. Average per-person Medicare payments for services to beneficiaries age ≥65 years with Alzheimer's or other dementias are more than three times as great as payments for beneficiaries without these conditions, and Medicaid payments are more than 23 times as great. Total payments in 2018 for health care, long-term care and hospice services for people age ≥65 years with dementia are estimated to be $277 billion. With the identification of AD biomarkers in recent years, our understanding of the disease has moved from one based on symptoms to one based on brain changes. Because these changes begin well before clinical symptoms arise, Alzheimer's has the potential to be diagnosed before the dementia stage. Early diagnosis of AD could have important personal and financial benefits. A mathematical model estimates that early and accurate diagnosis could save up to $7.9 trillion in medical and care costs.
AbstractList This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on caregivers and society. The Special Report examines the benefits of diagnosing Alzheimer's earlier in the disease process, in the stage of mild cognitive impairment due to Alzheimer's disease. An estimated 5.7 million Americans have Alzheimer's dementia. By mid-century, the number of people living with Alzheimer's dementia in the United States is projected to grow to 13.8 million, fueled in large part by the aging baby boom generation. In 2015, official death certificates recorded 110,561 deaths from AD, making AD the sixth leading cause of death in the United States and the fifth leading cause of death in Americans age ≥65 years. Between 2000 and 2015, deaths resulting from stroke, heart disease, and prostate cancer decreased, whereas deaths from AD increased 123%. In 2017, more than 16 million family members and other unpaid caregivers provided an estimated 18.4 billion hours of care to people with Alzheimer's or other dementias. This care is valued at more than $232 billion, but its costs extend to family caregivers' increased risk for emotional distress and negative mental and physical health outcomes. Average per-person Medicare payments for services to beneficiaries age ≥65 years with Alzheimer's or other dementias are more than three times as great as payments for beneficiaries without these conditions, and Medicaid payments are more than 23 times as great. Total payments in 2018 for health care, long-term care and hospice services for people age ≥65 years with dementia are estimated to be $277 billion. With the identification of AD biomarkers in recent years, our understanding of the disease has moved from one based on symptoms to one based on brain changes. Because these changes begin well before clinical symptoms arise, Alzheimer's has the potential to be diagnosed before the dementia stage. Early diagnosis of AD could have important personal and financial benefits. A mathematical model estimates that early and accurate diagnosis could save up to $7.9 trillion in medical and care costs.
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2018 The Alzheimer's Association
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Issue 3
Keywords Caregivers
Health care professional
Health care costs
Medicaid spending
Biomarker
Early diagnosis
Prevalence
Family caregiver
Mild cognitive impairment
Mortality
Preventable hospitalizations
Long-term care insurance
Risk factors
Morbidity
Early detection
Incidence
Health care expenditures
Long-term care costs
Spouse caregiver
Diagnostic criteria
Medicare spending
Alzheimer's dementia
Alzheimer's disease
Dementia
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2002; 155
2014; 26
2003; 58
1997; 49
2011; 59
2014; 29
2011; 58
2012; 367
2009; 119
2013; 5
2003; 51
2014; 23
1998; 88
2013; 9
2010; 23
2009; 12
2006; 20
2010; 25
2010; 24
2015; 84
1993; 33
2015; 85
2018; 178
2011; 73
2004; 292
2006; 163
2014; 14
2011; 68
2014; 19
2014; 18
2007; 3
2007; 64
2007; 68
2009; 16
2014; 12
2007; 69
2014; 11
2014; 10
2009; 17
2018; 29
2006; 54
2015; 50
1993; 43
2004; 140
2015; 55
2002; 8
2011; 77
2014; 41
2014; 45
2014; 42
2018; 17
2005; 19
2003; 349
2011; 305
2006; 43
2015; 63
2016; 176
2014; 39
2014; 30
2014; 383
2014; 33
2018; 14
2010; 50
2017; 5
2015; 35
2015; 34
2012; 60
2017; 7
2017; 8
2015; 105
2015; 30
2003; 13
2005; 21
2011; 13
2000; 2
2000; 1
2011; 12
2012; 58
2009; 49
2012; 52
2005; 25
2012; 172
2015; 48
2009; 57
2003; 129
2006; 61
1976; 33
2000; 54
2000; 55
2016; 87
2016; 86
2011; 21
2016; 512
2011; 26
2011; 25
2012; 69
2009; 23
2015; 14
2004; 226
2015; 17
2015; 16
2003; 138
2000; 21
2008; 18
2012; 1822
2015; 11
2015; 10
2009; 132
2011; 31
2016; 54
1998; 338
2016; 53
2016; 52
2006; 5
2016; 50
2013; 382
2017; 177
2012; 79
2012; 78
2011; 171
2016; 58
2009; 26
2016; 57
2005; 45
2016; 56
2012; 74
2009; 28
2017; 95
2015; 26
2009; 35
2015; 25
2012; 2
2015; 27
2015; 29
2015; 314
2002; 287
2002; 288
2016; 64
2013; 136
2005; 53
2016; 68
2005; 57
2012; 8
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e_1_2_10_342_2
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Petersen RC (e_1_2_10_159_2) 2018; 90
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Murphy SL (e_1_2_10_233_2) 2017; 66
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Harris‐Kojetin L (e_1_2_10_451_2) 2016; 38
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Snippet This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, costs of care, and...
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wiley
elsevier
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Publisher
StartPage 367
SubjectTerms Alzheimer's dementia
Alzheimer's disease
Biomarker
Caregivers
Dementia
Diagnostic criteria
Early detection
Early diagnosis
Family caregiver
Health care costs
Health care expenditures
Health care professional
Incidence
Long-term care costs
Long-term care insurance
Medicaid spending
Medicare spending
Mild cognitive impairment
Morbidity
Mortality
Prevalence
Preventable hospitalizations
Risk factors
Spouse caregiver
Title 2018 Alzheimer's disease facts and figures
URI https://dx.doi.org/10.1016/j.jalz.2018.02.001
https://onlinelibrary.wiley.com/doi/abs/10.1016%2Fj.jalz.2018.02.001
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