2018 Alzheimer's disease facts and figures
This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on caregivers and society. The Special Report examines the benefits of diagnosing Alzheimer's earlier in the disea...
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Published in | Alzheimer's & dementia Vol. 14; no. 3; pp. 367 - 429 |
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Format | Journal Article |
Language | English |
Published |
Elsevier Inc
01.03.2018
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Subjects | |
Online Access | Get full text |
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Abstract | This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on caregivers and society. The Special Report examines the benefits of diagnosing Alzheimer's earlier in the disease process, in the stage of mild cognitive impairment due to Alzheimer's disease. An estimated 5.7 million Americans have Alzheimer's dementia. By mid-century, the number of people living with Alzheimer's dementia in the United States is projected to grow to 13.8 million, fueled in large part by the aging baby boom generation. In 2015, official death certificates recorded 110,561 deaths from AD, making AD the sixth leading cause of death in the United States and the fifth leading cause of death in Americans age ≥65 years. Between 2000 and 2015, deaths resulting from stroke, heart disease, and prostate cancer decreased, whereas deaths from AD increased 123%. In 2017, more than 16 million family members and other unpaid caregivers provided an estimated 18.4 billion hours of care to people with Alzheimer's or other dementias. This care is valued at more than $232 billion, but its costs extend to family caregivers' increased risk for emotional distress and negative mental and physical health outcomes. Average per-person Medicare payments for services to beneficiaries age ≥65 years with Alzheimer's or other dementias are more than three times as great as payments for beneficiaries without these conditions, and Medicaid payments are more than 23 times as great. Total payments in 2018 for health care, long-term care and hospice services for people age ≥65 years with dementia are estimated to be $277 billion. With the identification of AD biomarkers in recent years, our understanding of the disease has moved from one based on symptoms to one based on brain changes. Because these changes begin well before clinical symptoms arise, Alzheimer's has the potential to be diagnosed before the dementia stage. Early diagnosis of AD could have important personal and financial benefits. A mathematical model estimates that early and accurate diagnosis could save up to $7.9 trillion in medical and care costs. |
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AbstractList | This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on caregivers and society. The Special Report examines the benefits of diagnosing Alzheimer's earlier in the disease process, in the stage of mild cognitive impairment due to Alzheimer's disease. An estimated 5.7 million Americans have Alzheimer's dementia. By mid-century, the number of people living with Alzheimer's dementia in the United States is projected to grow to 13.8 million, fueled in large part by the aging baby boom generation. In 2015, official death certificates recorded 110,561 deaths from AD, making AD the sixth leading cause of death in the United States and the fifth leading cause of death in Americans age ≥65 years. Between 2000 and 2015, deaths resulting from stroke, heart disease, and prostate cancer decreased, whereas deaths from AD increased 123%. In 2017, more than 16 million family members and other unpaid caregivers provided an estimated 18.4 billion hours of care to people with Alzheimer's or other dementias. This care is valued at more than $232 billion, but its costs extend to family caregivers' increased risk for emotional distress and negative mental and physical health outcomes. Average per-person Medicare payments for services to beneficiaries age ≥65 years with Alzheimer's or other dementias are more than three times as great as payments for beneficiaries without these conditions, and Medicaid payments are more than 23 times as great. Total payments in 2018 for health care, long-term care and hospice services for people age ≥65 years with dementia are estimated to be $277 billion. With the identification of AD biomarkers in recent years, our understanding of the disease has moved from one based on symptoms to one based on brain changes. Because these changes begin well before clinical symptoms arise, Alzheimer's has the potential to be diagnosed before the dementia stage. Early diagnosis of AD could have important personal and financial benefits. A mathematical model estimates that early and accurate diagnosis could save up to $7.9 trillion in medical and care costs. |
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Keywords | Caregivers Health care professional Health care costs Medicaid spending Biomarker Early diagnosis Prevalence Family caregiver Mild cognitive impairment Mortality Preventable hospitalizations Long-term care insurance Risk factors Morbidity Early detection Incidence Health care expenditures Long-term care costs Spouse caregiver Diagnostic criteria Medicare spending Alzheimer's dementia Alzheimer's disease Dementia |
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72 e_1_2_10_194_2 e_1_2_10_514_2 e_1_2_10_513_2 e_1_2_10_8_2 e_1_2_10_329_2 e_1_2_10_537_2 Murray ME (e_1_2_10_495_2) 2015; 138 e_1_2_10_306_2 Primetica B (e_1_2_10_357_2) 2015; 34 e_1_2_10_119_2 e_1_2_10_205_2 e_1_2_10_281_2 e_1_2_10_404_2 e_1_2_10_427_2 e_1_2_10_370_2 e_1_2_10_61_2 e_1_2_10_160_2 e_1_2_10_84_2 e_1_2_10_183_2 e_1_2_10_525_2 Mausbach BT (e_1_2_10_314_2) 2014; 29 e_1_2_10_524_2 McKhann GM (e_1_2_10_143_2) 2012 e_1_2_10_317_2 Epperly T (e_1_2_10_521_2) 2017; 95 e_1_2_10_270_2 e_1_2_10_403_2 e_1_2_10_415_2 e_1_2_10_438_2 e_1_2_10_206_2 e_1_2_10_229_2 e_1_2_10_73_2 e_1_2_10_96_2 e_1_2_10_172_2 e_1_2_10_195_2 e_1_2_10_535_2 e_1_2_10_9_2 Institute of Medicine (e_1_2_10_48_2) 2015 e_1_2_10_536_2 e_1_2_10_512_2 e_1_2_10_305_2 e_1_2_10_328_2 e_1_2_10_50_2 Petersen RC (e_1_2_10_159_2) 2018; 90 e_1_2_10_490_2 Murphy SL (e_1_2_10_233_2) 2017; 66 e_1_2_10_282_2 e_1_2_10_414_2 e_1_2_10_426_2 Harris‐Kojetin L (e_1_2_10_451_2) 2016; 38 e_1_2_10_392_2 e_1_2_10_449_2 e_1_2_10_218_2 e_1_2_10_85_2 e_1_2_10_161_2 e_1_2_10_184_2 |
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SubjectTerms | Alzheimer's dementia Alzheimer's disease Biomarker Caregivers Dementia Diagnostic criteria Early detection Early diagnosis Family caregiver Health care costs Health care expenditures Health care professional Incidence Long-term care costs Long-term care insurance Medicaid spending Medicare spending Mild cognitive impairment Morbidity Mortality Prevalence Preventable hospitalizations Risk factors Spouse caregiver |
Title | 2018 Alzheimer's disease facts and figures |
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