Disseminated tuberculosis complicating anti‐TNF‐α treatment
Summary An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for rheumatoid arthritis or Crohn's disease. We describe a patient with rheumatoid arthritis who was treated with infliximab and became...
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Published in | International journal of clinical practice (Esher) Vol. 58; no. 11; pp. 1052 - 1055 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK; Malden, USA
Blackwell Science Ltd
01.11.2004
Blackwell Hindawi Limited |
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Abstract | Summary
An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for rheumatoid arthritis or Crohn's disease. We describe a patient with rheumatoid arthritis who was treated with infliximab and became systemically ill with Mycobacterium tuberculosis‐disseminated infection. Patients who are candidates for treatment with tumour necrosis factor‐alfa inhibitors should be evaluated for the presence of latent or active M. tuberculosis infection. |
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AbstractList | An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for rheumatoid arthritis or Crohn's disease. We describe a patient with rheumatoid arthritis who was treated with infliximab and became systemically ill with Mycobacterium tuberculosis-disseminated infection. Patients who are candidates for treatment with tumour necrosis factor-alfa inhibitors should be evaluated for the presence of latent or active Summary An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for rheumatoid arthritis or Crohn's disease. We describe a patient with rheumatoid arthritis who was treated with infliximab and became systemically ill with Mycobacterium tuberculosis‐disseminated infection. Patients who are candidates for treatment with tumour necrosis factor‐alfa inhibitors should be evaluated for the presence of latent or active M. tuberculosis infection. An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for rheumatoid arthritis or Crohn's disease. We describe a patient with rheumatoid arthritis who was treated with infliximab and became systemically ill with Mycobacterium tuberculosis-disseminated infection. Patients who are candidates for treatment with tumour necrosis factor-alfa inhibitors should be evaluated for the presence of latent or active M. tuberculosis infection.[PUBLICATION ABSTRACT] |
Author | Latsi, P. Dimakou, K. Papaioannides, D. Katsimboula, S. Orphanidou, D. Korantzopoulos, P. |
Author_xml | – sequence: 1 givenname: K. surname: Dimakou fullname: Dimakou, K. – sequence: 2 givenname: D. surname: Papaioannides fullname: Papaioannides, D. – sequence: 3 givenname: P. surname: Latsi fullname: Latsi, P. – sequence: 4 givenname: S. surname: Katsimboula fullname: Katsimboula, S. – sequence: 5 givenname: P. surname: Korantzopoulos fullname: Korantzopoulos, P. – sequence: 6 givenname: D. surname: Orphanidou fullname: Orphanidou, D. |
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Keywords | Infection Medicine Treatment Tuberculosis Bacteriosis Complication Mycobacterial infection Disseminated Tumor necrosis factor α |
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An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy... An unusually large number of cases of tuberculosis, often of miliary or disseminated form, have been reported in patients receiving infliximab therapy for... |
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SubjectTerms | Antibodies, Monoclonal Antirheumatic Agents anti‐TNF‐α treatment Arthritis, Rheumatoid - drug therapy Bacterial diseases Biological and medical sciences Case studies Contraindications Drug therapy Female General aspects Human bacterial diseases Humans Infectious diseases Infliximab Medical sciences Medical treatment Middle Aged Miliary tuberculosis Opportunistic Infections - complications Opportunistic Infections - diagnostic imaging Rheumatoid arthritis Tomography, X-Ray Computed Tuberculosis Tuberculosis and atypical mycobacterial infections Tuberculosis, Miliary - complications Tuberculosis, Miliary - diagnostic imaging Tuberculosis, Pulmonary - complications Tuberculosis, Pulmonary - diagnostic imaging Tumor Necrosis Factor-alpha - antagonists & inhibitors |
Title | Disseminated tuberculosis complicating anti‐TNF‐α treatment |
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