Analysis of the treg cell population in the peripheral blood of ovarian cancer patients in relation to the long-term outcomes

• Published in: Ginekologia polska Vol. 90; no. 4; pp. 179 - 184
• Main Authors: Dutsch-Wicherek, Magdalena Maria, Szubert, Sebastian, Dziobek, Konrad, Wisniewski, Michal, Lukaszewska, Ewelina, Wicherek, Lukasz, Jozwicki, Wojciech, Rokita, Wojciech, Koper, Krzysztof
• Format: Journal Article
• Language: English
• Published: Poland Wydawnictwo Via Medica 01.01.2019
• Subjects: Adult; Aged; Aged, 80 and over; Cancer therapies; Chemotherapy; Female; Flow Cytometry; Follow-Up Studies; Humans; Medical prognosis; Middle Aged; Ovarian cancer; Ovarian Neoplasms - blood; Ovarian Neoplasms - immunology; Ovarian Neoplasms - mortality; Ovarian Neoplasms - therapy; Poland; Population; Survival Analysis; T-Lymphocytes, Regulatory - cytology; T-Lymphocytes, Regulatory - immunology; Treatment Outcome; Poland; tumor immunology; regulatory T-cells; ovarian cancer; Tregs

There is growing evidence that Treg cell infiltration into the cancer nest is associated with poor prognosis. How- ever, the Treg cell population in the peripheral blood may change when a different type of anticancer therapy is applied. Since Treg cells may support tumor growth by enhancing the supp...