Neonatal hypoxic ischemic encephalopathy-related biomarkers in serum and cerebrospinal fluid

• Published in: Clinica chimica acta Vol. 450; pp. 282 - 297
• Main Authors: Lv, Hongyan, Wang, Qiuli, Wu, Sujing, Yang, Lihong, Ren, Pengshun, Yang, Yihui, Gao, Jinsheng, Li, Lianxiang
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 23.10.2015
• Subjects: Animals; Biomarker; Biomarkers - blood; Biomarkers - cerebrospinal fluid; Cerebrospinal fluid; Humans; Hypoxia-Ischemia, Brain - blood; Hypoxia-Ischemia, Brain - cerebrospinal fluid; Hypoxic ischemic encephalopathy; Infant, Newborn; Newborn; Serum; Biomarker; UCH-L1; ICAM-1; MDA; Cerebrospinal fluid; sLCAM-1; LDH; CSF; CK-BB; miRNA; Hs-CRP; Serum; MBP; NSE; IL; HIE; BDNF; VEGF; SOD; Hypoxic ischemic encephalopathy; Newborn; FAP; TNF-α; MIR; ATP; MMP-9

Neonatal hypoxic ischemic encephalopathy (HIE) is a common disease caused by perinatal asphyxia, a major cause of neonatal death, neurological behavior, and long-term disability. Currently, the diagnosis and prognosis of neonatal HIE are based on nervous system clinical manifestations, imaging and e...