BRCA1 and BRCA2 germline mutations in Korean ovarian cancer patients
Purpose To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Methods and patients Pedigree analysis and genetic counseling were performed on 337 ovarian cancer patients in the National Cancer Center Korea between January 2...
Saved in:
Published in | Journal of cancer research and clinical oncology Vol. 135; no. 11; pp. 1593 - 1599 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Berlin/Heidelberg
Berlin/Heidelberg : Springer-Verlag
01.11.2009
Springer-Verlag Springer Springer Nature B.V |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Purpose To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Methods and patients Pedigree analysis and genetic counseling were performed on 337 ovarian cancer patients in the National Cancer Center Korea between January 2005 and June 2008. Patients with a strong family history were defined as (1) patients with double primary ovarian and breast cancer and (2) ovarian cancer patients with one or more first-degree relatives with breast or ovarian cancer. Lymphocyte specimens from peripheral blood were processed for BRCA1 and BRCA2 by direct sequencing. Results Sixteen percent (54/337) of patients had a strong family history. Of the 54 patients with a strong family history, 40 patients (74%) accepted the genetic test. Thirteen deleterious mutations (11 in BRCA1 and 2 in BRCA2) were identified (33%). Twenty-three of 283 patients (8%) without a strong family history underwent genetic testing and two deleterious mutations in BRCA1 were identified (9%). Eight of 15 mutations (53%) were novel, and c.1041delAGCinsT and c.2081insC in the BRCA1 gene were recurrent in two patients. Conclusions The proportion of Korean ovarian cancer patients with a strong family history was significant, and the prevalence of BRCA1 and BRCA2 mutations in such patients was high. |
---|---|
AbstractList | PURPOSETo evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. METHODS AND PATIENTSPedigree analysis and genetic counseling were performed on 337 ovarian cancer patients in the National Cancer Center Korea between January 2005 and June 2008. Patients with a strong family history were defined as (1) patients with double primary ovarian and breast cancer and (2) ovarian cancer patients with one or more first-degree relatives with breast or ovarian cancer. Lymphocyte specimens from peripheral blood were processed for BRCA1 and BRCA2 by direct sequencing. RESULTSSixteen percent (54/337) of patients had a strong family history. Of the 54 patients with a strong family history, 40 patients (74%) accepted the genetic test. Thirteen deleterious mutations (11 in BRCA1 and 2 in BRCA2) were identified (33%). Twenty-three of 283 patients (8%) without a strong family history underwent genetic testing and two deleterious mutations in BRCA1 were identified (9%). Eight of 15 mutations (53%) were novel, and c.1041delAGCinsT and c.2081insC in the BRCA1 gene were recurrent in two patients. CONCLUSIONSThe proportion of Korean ovarian cancer patients with a strong family history was significant, and the prevalence of BRCA1 and BRCA2 mutations in such patients was high. To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Pedigree analysis and genetic counseling were performed on 337 ovarian cancer patients in the National Cancer Center Korea between January 2005 and June 2008. Patients with a strong family history were defined as (1) patients with double primary ovarian and breast cancer and (2) ovarian cancer patients with one or more first-degree relatives with breast or ovarian cancer. Lymphocyte specimens from peripheral blood were processed for BRCA1 and BRCA2 by direct sequencing. Sixteen percent (54/337) of patients had a strong family history. Of the 54 patients with a strong family history, 40 patients (74%) accepted the genetic test. Thirteen deleterious mutations (11 in BRCA1 and 2 in BRCA2) were identified (33%). Twenty-three of 283 patients (8%) without a strong family history underwent genetic testing and two deleterious mutations in BRCA1 were identified (9%). Eight of 15 mutations (53%) were novel, and c.1041delAGCinsT and c.2081insC in the BRCA1 gene were recurrent in two patients. The proportion of Korean ovarian cancer patients with a strong family history was significant, and the prevalence of BRCA1 and BRCA2 mutations in such patients was high. [PUBLICATION ABSTRACT] Purpose To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Methods and patients Pedigree analysis and genetic counseling were performed on 337 ovarian cancer patients in the National Cancer Center Korea between January 2005 and June 2008. Patients with a strong family history were defined as (1) patients with double primary ovarian and breast cancer and (2) ovarian cancer patients with one or more first-degree relatives with breast or ovarian cancer. Lymphocyte specimens from peripheral blood were processed for BRCA1 and BRCA2 by direct sequencing. Results Sixteen percent (54/337) of patients had a strong family history. Of the 54 patients with a strong family history, 40 patients (74%) accepted the genetic test. Thirteen deleterious mutations (11 in BRCA1 and 2 in BRCA2 ) were identified (33%). Twenty-three of 283 patients (8%) without a strong family history underwent genetic testing and two deleterious mutations in BRCA1 were identified (9%). Eight of 15 mutations (53%) were novel, and c.1041delAGCinsT and c.2081insC in the BRCA1 gene were recurrent in two patients. Conclusions The proportion of Korean ovarian cancer patients with a strong family history was significant, and the prevalence of BRCA1 and BRCA2 mutations in such patients was high. To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Pedigree analysis and genetic counseling were performed on 337 ovarian cancer patients in the National Cancer Center Korea between January 2005 and June 2008. Patients with a strong family history were defined as (1) patients with double primary ovarian and breast cancer and (2) ovarian cancer patients with one or more first-degree relatives with breast or ovarian cancer. Lymphocyte specimens from peripheral blood were processed for BRCA1 and BRCA2 by direct sequencing. Sixteen percent (54/337) of patients had a strong family history. Of the 54 patients with a strong family history, 40 patients (74%) accepted the genetic test. Thirteen deleterious mutations (11 in BRCA1 and 2 in BRCA2) were identified (33%). Twenty-three of 283 patients (8%) without a strong family history underwent genetic testing and two deleterious mutations in BRCA1 were identified (9%). Eight of 15 mutations (53%) were novel, and c.1041delAGCinsT and c.2081insC in the BRCA1 gene were recurrent in two patients. The proportion of Korean ovarian cancer patients with a strong family history was significant, and the prevalence of BRCA1 and BRCA2 mutations in such patients was high. Purpose To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Methods and patients Pedigree analysis and genetic counseling were performed on 337 ovarian cancer patients in the National Cancer Center Korea between January 2005 and June 2008. Patients with a strong family history were defined as (1) patients with double primary ovarian and breast cancer and (2) ovarian cancer patients with one or more first-degree relatives with breast or ovarian cancer. Lymphocyte specimens from peripheral blood were processed for BRCA1 and BRCA2 by direct sequencing. Results Sixteen percent (54/337) of patients had a strong family history. Of the 54 patients with a strong family history, 40 patients (74%) accepted the genetic test. Thirteen deleterious mutations (11 in BRCA1 and 2 in BRCA2) were identified (33%). Twenty-three of 283 patients (8%) without a strong family history underwent genetic testing and two deleterious mutations in BRCA1 were identified (9%). Eight of 15 mutations (53%) were novel, and c.1041delAGCinsT and c.2081insC in the BRCA1 gene were recurrent in two patients. Conclusions The proportion of Korean ovarian cancer patients with a strong family history was significant, and the prevalence of BRCA1 and BRCA2 mutations in such patients was high. |
Author | Kang, Sokbom Seo, Sang-Soo Lee, Bo-Yon Lee, Seon-Kyung Lim, Myong Cheol Kong, Sun-Young Park, Sang-Yoon |
Author_xml | – sequence: 1 fullname: Lim, Myong Cheol – sequence: 2 fullname: Kang, Sokbom – sequence: 3 fullname: Seo, Sang-Soo – sequence: 4 fullname: Kong, Sun-Young – sequence: 5 fullname: Lee, Bo-Yon – sequence: 6 fullname: Lee, Seon-Kyung – sequence: 7 fullname: Park, Sang-Yoon |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21959470$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/19499246$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kE1v1DAQhi1URLeFH8AFIiS4BWbs2F4fy_IpKiEBPVt2MqlSJfZiJ0j8exxlRSUOnMYfz7wzei7YWYiBGHuK8BoB9JsM0AheA5gaFOhaPGA7XF9QCHnGdoAaa8lRnbOLnO-g3KXmj9g5msYY3qgde_f22-EKKxe6aj3x6pbSNA6BqmmZ3TzEkKshVF9iIheq-MulodTWhZZSdSwAhTk_Zg97N2Z6cqqX7ObD-x-HT_X114-fD1fXddtwMdckBDrvvds3yjtSqvOmRew7aHvdydY3Hgm0E0Z0pPdeG-QkyTdSezBKiUv2ass9pvhzoTzbacgtjaMLFJdslVZyr6Us4It_wLu4pFB2s5yDBGPEmoYb1KaYc6LeHtMwufTbItjVr9382uLXrn6tKD3PTsGLn6i77zgJLcDLE-By68Y-FVND_stxNNI0GgrHNy6Xr1Ck32_4v-nPt6beRetuUwm--c4BBaDaIzdK_AGgPJtm |
CODEN | JCROD7 |
CitedBy_id | crossref_primary_10_1155_2014_787143 crossref_primary_10_1186_s12885_018_5235_3 crossref_primary_10_4143_crt_2016_135 crossref_primary_10_3802_jgo_2017_28_e51 crossref_primary_10_1111_jog_13287 crossref_primary_10_1016_j_annpat_2020_02_015 crossref_primary_10_3390_ijms24087262 crossref_primary_10_1093_jjco_hyy111 crossref_primary_10_1016_j_ajhg_2020_08_001 crossref_primary_10_1016_j_tranon_2020_100863 crossref_primary_10_1007_s13369_016_2139_x crossref_primary_10_1097_IGC_0000000000001161 crossref_primary_10_1186_s12885_018_4700_3 crossref_primary_10_3802_jgo_2017_28_e39 crossref_primary_10_1097_IGC_0000000000001065 crossref_primary_10_3389_fonc_2021_674965 crossref_primary_10_1016_j_tjog_2014_11_003 crossref_primary_10_1007_s00432_015_2051_x crossref_primary_10_1007_s10549_012_2159_5 crossref_primary_10_18632_oncotarget_20428 crossref_primary_10_3802_jgo_2018_29_e43 crossref_primary_10_3802_jgo_2012_23_1_72 crossref_primary_10_4143_crt_2018_312 crossref_primary_10_1186_s13048_019_0560_y crossref_primary_10_3802_jgo_2016_27_e36 crossref_primary_10_3802_jgo_2019_30_e80 crossref_primary_10_1016_j_ejso_2019_09_002 crossref_primary_10_1097_IGC_0000000000000964 crossref_primary_10_1097_IGC_0b013e31823b3650 crossref_primary_10_3802_jgo_2017_28_e61 crossref_primary_10_3802_jgo_2013_24_4_298 crossref_primary_10_5734_JGM_2013_10_2_124 crossref_primary_10_5468_ogs_2015_58_2_175 crossref_primary_10_1016_j_gore_2019_07_007 crossref_primary_10_3802_jgo_2019_30_e38 crossref_primary_10_4143_crt_2020_364 crossref_primary_10_5306_wjco_v10_i11_358 crossref_primary_10_5468_ogs_2019_62_6_411 crossref_primary_10_1111_cas_15166 crossref_primary_10_3802_jgo_2017_28_e3 crossref_primary_10_3802_jgo_2020_31_e83 crossref_primary_10_1093_jjco_hyq144 crossref_primary_10_3802_jgo_2014_25_4_342 crossref_primary_10_1097_IGC_0b013e3182332cd1 crossref_primary_10_1097_IGC_0000000000000529 crossref_primary_10_1038_npjgenmed_2015_3 |
Cites_doi | 10.1002/humu.9059 10.1001/jama.283.17.2260 10.1111/j.1525-1438.2007.00824.x 10.1158/1055-9965.EPI-05-0687 10.1002/humu.20169 10.1002/ijc.1626 10.1002/ijc.11338 10.1086/318787 10.1002/humu.9275 10.1016/j.ygyno.2005.06.058 10.1086/302853 10.1093/jnci/djj465 10.1002/1098-1004(200007)16:1<88::AID-HUMU16>3.0.CO;2-G 10.1016/j.critrevonc.2008.06.003 10.1200/JCO.2004.04.179 10.1002/ijc.22269 10.1034/j.1399-0004.1999.550504.x 10.1002/ijc.1627 10.1002/humu.10154 10.1038/sj.ejhg.5200652 10.1086/342506 10.1086/521032 10.1002/(SICI)1097-0215(20000601)86:5<737::AID-IJC21>3.0.CO;2-1 10.1006/gyno.2000.5848 10.1002/cncr.21536 10.1007/s100380050035 10.1016/j.canlet.2005.12.031 10.1056/NEJM200107263450401 10.3346/jkms.2004.19.2.269 10.4143/crt.2003.35.1.3 10.1200/JCO.2001.19.8.2247 10.1038/bjc.1989.320 |
ContentType | Journal Article |
Copyright | Springer-Verlag 2009 2009 INIST-CNRS |
Copyright_xml | – notice: Springer-Verlag 2009 – notice: 2009 INIST-CNRS |
DBID | FBQ IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 3V. 7TO 7X7 7XB 88E 8AO 8C1 8FI 8FJ 8FK 8G5 ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH GNUQQ GUQSH H94 K9. M0S M1P M2O MBDVC PQEST PQQKQ PQUKI PRINS Q9U 7X8 |
DOI | 10.1007/s00432-009-0607-3 |
DatabaseName | AGRIS Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef ProQuest Central (Corporate) Oncogenes and Growth Factors Abstracts ProQuest Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection ProQuest Public Health Database Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni Edition) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student Research Library Prep AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) ProQuest Research Library Research Library (Corporate) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Research Library Prep ProQuest Central Student Oncogenes and Growth Factors Abstracts ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College Research Library (Alumni Edition) ProQuest Pharma Collection ProQuest Central China ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea AIDS and Cancer Research Abstracts ProQuest Research Library ProQuest Medical Library (Alumni) ProQuest Public Health ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest Central (Alumni) MEDLINE - Academic |
DatabaseTitleList | MEDLINE - Academic Research Library Prep MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database – sequence: 4 dbid: FBQ name: AGRIS url: http://www.fao.org/agris/Centre.asp?Menu_1ID=DB&Menu_2ID=DB1&Language=EN&Content=http://www.fao.org/agris/search?Language=EN sourceTypes: Publisher |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1432-1335 |
EndPage | 1599 |
ExternalDocumentID | 1865613771 10_1007_s00432_009_0607_3 19499246 21959470 US201301681296 |
Genre | Journal Article |
GeographicLocations | Asia Korea |
GroupedDBID | --- -53 -5E -5G -BR -EM -Y2 -~C -~X .55 .86 .GJ .VR 06C 06D 0R~ 0VY 199 1N0 1SB 2.D 203 28- 29K 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 36B 3O- 3V. 4.4 406 408 409 40D 40E 53G 5QI 5RE 5VS 67Z 6NX 78A 7X7 88E 8AO 8C1 8FI 8FJ 8G5 8UJ 95- 95. 95~ 96X AAAVM AABHQ AABYN AAFGU AAHNG AAIAL AAJKR AAKSU AANXM AANZL AARHV AARTL AATNV AATVU AAUYE AAWCG AAYFA AAYIU AAYOK AAYQN AAYTO ABBBX ABBXA ABDZT ABECU ABFGW ABFTV ABHLI ABHQN ABIPD ABJNI ABJOX ABKAS ABKCH ABKTR ABLJU ABMNI ABMQK ABNWP ABPLI ABPTK ABSXP ABTEG ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACBMV ACBRV ACBXY ACBYP ACGFS ACHSB ACHVE ACHXU ACIGE ACIPQ ACKNC ACMDZ ACMLO ACOKC ACOMO ACPRK ACTTH ACUDM ACVWB ACWMK ADBBV ADHHG ADHIR ADINQ ADKNI ADKPE ADMDM ADOXG ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEEQQ AEFIE AEFTE AEGAL AEGNC AEJHL AEJRE AEKMD AENEX AEOHA AEPYU AEQTP AESKC AESTI AETLH AEVLU AEVTX AEXYK AFAFS AFEXP AFFNX AFKRA AFLOW AFNRJ AFQWF AFWTZ AFZKB AGAYW AGDGC AGGBP AGGDS AGJBK AGKHE AGMZJ AGQMX AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHKAY AHMBA AHSBF AHYZX AIAKS AIIXL AILAN AIMYW AITGF AJBLW AJDOV AJRNO AJZVZ AKMHD AKQUC ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARMRJ ASPBG AVWKF AXYYD AZFZN AZQEC B-. BA0 BBWZM BDATZ BENPR BGNMA BPHCQ BVXVI CAG CCPQU COF CS3 CSCUP D-I DDRTE DL5 DNIVK DPUIP DU5 DWQXO EBD EBLON EBS EIOEI EJD EMB EMOBN EN4 ESBYG F5P FBQ FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNUQQ GNWQR GQ6 GQ7 GQ8 GRRUI GUQSH GXS HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 IHE IJ- IKXTQ IMOTQ ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KOW KPH LAS LLZTM M1P M2O M4Y MA- N2Q N9A NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM OVD P19 P2P P9S PF0 PQQKQ PROAC PSQYO PT4 PT5 Q2X QOK QOR QOS R89 R9I RHV RIG RNI ROL RPX RRX RSV RZK S16 S1Z S26 S27 S28 S37 S3B SAP SCLPG SDE SDH SDM SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZ9 SZN T13 T16 TEORI TSG TSK TSV TT1 TUC U2A U9L UG4 UKHRP UNUBA UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WJK WK8 X7M YLTOR Z45 Z7U Z7W Z7X Z82 Z83 Z87 Z8O Z8Q Z8V Z8W Z91 ZGI ZMTXR ZOVNA ZXP ~EX ~KM AAUGY H13 IQODW AAEOY AAKKN AAYZH ABAKF ABEEZ ACACY ACULB ACZOJ AEFQL AFBBN AFGXO AGQEE AGRTI AJOOF ALIPV C24 C6C CGR CUY CVF ECM EIF NPM AAYXX CITATION 7TO 7XB 8FK H94 K9. MBDVC PQEST PQUKI PRINS Q9U 7X8 |
ID | FETCH-LOGICAL-c423t-e331abbba846bae66db9c11fd0cf7d5cb4b1e07a393de78b7912e5eb457b09663 |
IEDL.DBID | AGYKE |
ISSN | 0171-5216 |
IngestDate | Fri Aug 16 22:25:15 EDT 2024 Thu Oct 10 17:26:56 EDT 2024 Thu Sep 12 17:14:26 EDT 2024 Tue Oct 15 23:34:28 EDT 2024 Sun Oct 22 16:04:48 EDT 2023 Sat Dec 16 12:01:10 EST 2023 Wed Dec 27 19:12:46 EST 2023 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 11 |
Keywords | Germline mutation Genetics Ovarian cancer Human Ovary cancer Patient Malignant tumor BRCA1 BRCA2 Female genital diseases Genetic disease Ovarian diseases BRCA2 gene BRCA1 gene Cancer Tumor suppressor gene |
Language | English |
License | CC BY 4.0 |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c423t-e331abbba846bae66db9c11fd0cf7d5cb4b1e07a393de78b7912e5eb457b09663 |
Notes | http://dx.doi.org/10.1007/s00432-009-0607-3 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 19499246 |
PQID | 220509936 |
PQPubID | 47182 |
PageCount | 7 |
ParticipantIDs | proquest_miscellaneous_67658755 proquest_journals_220509936 crossref_primary_10_1007_s00432_009_0607_3 pubmed_primary_19499246 pascalfrancis_primary_21959470 springer_journals_10_1007_s00432_009_0607_3 fao_agris_US201301681296 |
PublicationCentury | 2000 |
PublicationDate | 2009-11-01 |
PublicationDateYYYYMMDD | 2009-11-01 |
PublicationDate_xml | – month: 11 year: 2009 text: 2009-11-01 day: 01 |
PublicationDecade | 2000 |
PublicationPlace | Berlin/Heidelberg |
PublicationPlace_xml | – name: Berlin/Heidelberg – name: Heidelberg – name: Germany |
PublicationTitle | Journal of cancer research and clinical oncology |
PublicationTitleAbbrev | J Cancer Res Clin Oncol |
PublicationTitleAlternate | J Cancer Res Clin Oncol |
PublicationYear | 2009 |
Publisher | Berlin/Heidelberg : Springer-Verlag Springer-Verlag Springer Springer Nature B.V |
Publisher_xml | – name: Berlin/Heidelberg : Springer-Verlag – name: Springer-Verlag – name: Springer – name: Springer Nature B.V |
References | Kang, Kim, Park, Kwon, Won, Heo, Lee, Kim, Shin, Noh, Yang, Choe, Lee, King, Park (CR11) 2002; 20 Menkiszak, Gronwald, Gorski, Jakubowska, Huzarski, Byrski, Foszczynska-Kloda, Haus, Janiszewska, Perkowska, Brozek, Grzybowska, Zientek, Gozdz, Kozak-Klonowska, Urbanski, Miturski, Kowalczyk, Pluzanska, Niepsuj, Koc, Szwiec, Drosik, Mackiewicz, Lamperska, Strozyk, Godlewski, Stawicka, Wasko, Bebenek, Rozmiarek, Rzepka-Gorska, Narod, Lubinski (CR21) 2003; 106 Modan, Hartge, Hirsh-Yechezkel, Chetrit, Lubin, Beller, Ben-Baruch, Fishman, Menczer, Ebbers, Tucker, Wacholder, Struewing, Friedman, Piura (CR22) 2001; 345 Khoo, Ngan, Cheung, Chan, Lu, Chan, Lau, Andrulis, Ozcelik (CR13) 2000; 16 Pal, Permuth-Wey, Betts, Krischer, Fiorica, Arango, LaPolla, Hoffman, Martino, Wakeley, Wilbanks, Nicosia, Cantor, Sutphen (CR25) 2005; 104 Van Der Looij, Szabo, Besznyak, Liszka, Csokay, Pulay, Toth, Devilee, King, Olah (CR36) 2000; 86 Choi, Lee, Bail, Carter, Haffy (CR6) 2003; 35 Boyd, Sonoda, Federici, Bogomolniy, Rhei, Maresco, Saigo, Almadrones, Barakat, Brown, Chi, Curtin, Poynor, Hoskins (CR5) 2000; 283 Chung, Hwang, Jung, Won, Shin, Kim, Lee (CR8) 2007; 17 Rashid, Zaidi, Torres, Sultan, Benner, Naqvi, Shakoori, Seidel-Renkert, Farooq, Narod, Amin, Hamann (CR26) 2006; 119 Tobias, Eng, McCurdy, Kalir, Mandelli, Dottino, Cohen (CR34) 2000; 78 Kim, Nam, Yoon, Kim, Kim, Kim, Kim, Koo, Kim (CR14) 2005; 99 Sarantaus, Vahteristo, Bloom, Tamminen, Unkila-Kallio, Butzow, Nevanlinna (CR30) 2001; 9 Szabo, King (CR33) 1997; 60 de la Hoya, Osorio, Godino, Sulleiro, Tosar, Perez-Segura, Fernandez, Rodriguez, Diaz-Rubio, Benitez, Devilee, Caldes (CR9) 2002; 97 Narod (CR24) 2005 Seo, Cho, Ahn, Yoon, Kang, Cho, Lee, Choe, Choi, Kim, Shin, Kim, Kim, Son, Lee, Koo (CR32) 2004; 24 Liede, Narod (CR16) 2002; 20 Mazoyer (CR19) 2005; 25 Moslehi, Chu, Karlan, Fishman, Risch, Fields, Smotkin, Ben-David, Rosenblatt, Russo, Schwartz, Tung, Warner, Rosen, Friedman, Brunet, Narod (CR23) 2000; 66 Liede, Malik, Aziz, Rios Pd Pde, Kwan, Narod (CR17) 2002; 71 Berek, Natarajan (CR3) 2007 Sekine, Nagata, Tsuji, Hirai, Fujimoto, Hatae, Kobayashi, Fujii, Nagata, Ushijima, Obata, Suzuki, Yoshinaga, Umesaki, Satoh, Enomoto, Motoyama, Tanaka (CR31) 2001; 7 Martin, Blackwood, Antin-Ozerkis, Shih, Calzone, Colligon, Seal, Collins, Stratton, Weber, Nathanson (CR18) 2001; 19 Russo, Calo, Bruno, Rizzo, Bazan, Di Fede (CR29) 2009; 69 Booth, Beral, Smith (CR4) 1989; 60 Ahn, Son, Yoon, Noh, Han, Kim, Lee, Park, Hong, Choi, Moon, Kim, Kim, Kwak, Cho (CR2) 2007; 245 Meindl (CR20) 2002; 97 Ahn, Hwang, Kwak, Yoon, Ku, Kang, Kim, Ko, Ko, Yoon, Cho, Kim, Son (CR1) 2004; 19 Katagiri, Kasumi, Yoshimoto, Nomizu, Asaishi, Abe, Tsuchiya, Sugano, Takai, Yoneda, Fukutomi, Nanba, Makita, Okazaki, Hirata, Okazaki, Furutsuma, Morishita, Iino, Karino, Ayabe, Hara, Kajiwara, Houga, Miki (CR12) 1998; 43 Easton, Deffenbaugh, Pruss, Frye, Wenstrup, Allen-Brady, Tavtigian, Monteiro, Iversen, Couch, Goldgar (CR10) 2007; 81 Lee, John, McGuire, Felberg, Ostrow, DiCioccio, Li, Miron, West, Whittemore (CR15) 2006; 15 Risch, McLaughlin, Cole, Rosen, Bradley, Kwan, Jack, Vesprini, Kuperstein, Abrahamson, Fan, Wong, Narod (CR27) 2001; 68 Tonin, Mes-Masson, Narod, Ghadirian, Provencher (CR35) 1999; 55 Risch, McLaughlin, Cole, Rosen, Bradley, Fan, Tang, Li, Zhang, Shaw, Narod (CR28) 2006; 98 Choi, Lee, Bale, Carter, Haffty (CR7) 2004; 22 17148771 - J Natl Cancer Inst. 2006 Dec 6;98(23):1694-706 17300678 - Int J Gynecol Cancer. 2007 May-Jun;17(3):595-600 15832305 - Hum Mutat. 2005 May;25(5):415-22 12181777 - Am J Hum Genet. 2002 Sep;71(3):595-606 12918074 - Int J Cancer. 2003 Oct 10;106(6):942-5 11802208 - Int J Cancer. 2002 Feb 1;97(4):466-71 10926794 - Gynecol Oncol. 2000 Aug;78(2):148-51 10797299 - Int J Cancer. 2000 Jun 1;86(5):737-40 11474660 - N Engl J Med. 2001 Jul 26;345(4):235-40 11595708 - Clin Cancer Res. 2001 Oct;7(10):3144-50 10739756 - Am J Hum Genet. 2000 Apr;66(4):1259-72 9609997 - J Hum Genet. 1998;43(1):42-8 11802209 - Int J Cancer. 2002 Feb 1;97(4):472-80 16284991 - Cancer. 2005 Dec 15;104(12):2807-16 15117986 - J Clin Oncol. 2004 May 1;22(9):1638-45 16455195 - Cancer Lett. 2007 Jan 8;245(1-2):90-5 9150148 - Am J Hum Genet. 1997 May;60(5):1013-20 16998791 - Int J Cancer. 2006 Dec 15;119(12):2832-9 17924331 - Am J Hum Genet. 2007 Nov;81(5):873-83 11436123 - Eur J Hum Genet. 2001 Jun;9(6):424-30 16084575 - Gynecol Oncol. 2005 Dec;99(3):585-90 2679848 - Br J Cancer. 1989 Oct;60(4):592-8 15082902 - J Korean Med Sci. 2004 Apr;19(2):269-74 16492929 - Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):359-63 10807385 - JAMA. 2000 May 3;283(17):2260-5 18656380 - Crit Rev Oncol Hematol. 2009 Jan;69(1):28-44 11304778 - J Clin Oncol. 2001 Apr 15;19(8):2247-53 11179017 - Am J Hum Genet. 2001 Mar;68(3):700-10 15365993 - Hum Mutat. 2004 Oct;24(4):350 10874312 - Hum Mutat. 2000 Jul;16(1):88-9 12442265 - Hum Mutat. 2002 Dec;20(6):413-24 12204006 - Hum Mutat. 2002 Sep;20(3):235 10422801 - Clin Genet. 1999 May;55(5):318-24 J Boyd (607_CR5) 2000; 283 R Moslehi (607_CR23) 2000; 66 M Booth (607_CR4) 1989; 60 SA Narod (607_CR24) 2005 DH Choi (607_CR7) 2004; 22 S Mazoyer (607_CR19) 2005; 25 A Russo (607_CR29) 2009; 69 B Modan (607_CR22) 2001; 345 HA Risch (607_CR28) 2006; 98 M Looij Van Der (607_CR36) 2000; 86 M Hoya de la (607_CR9) 2002; 97 PN Tonin (607_CR35) 1999; 55 SH Ahn (607_CR1) 2004; 19 A Liede (607_CR16) 2002; 20 AM Martin (607_CR18) 2001; 19 HC Kang (607_CR11) 2002; 20 HA Risch (607_CR27) 2001; 68 A Liede (607_CR17) 2002; 71 JS Berek (607_CR3) 2007 DF Easton (607_CR10) 2007; 81 MU Rashid (607_CR26) 2006; 119 DH Tobias (607_CR34) 2000; 78 J Menkiszak (607_CR21) 2003; 106 T Pal (607_CR25) 2005; 104 YT Kim (607_CR14) 2005; 99 L Sarantaus (607_CR30) 2001; 9 M Sekine (607_CR31) 2001; 7 T Katagiri (607_CR12) 1998; 43 DH Choi (607_CR6) 2003; 35 HH Chung (607_CR8) 2007; 17 JS Lee (607_CR15) 2006; 15 JH Seo (607_CR32) 2004; 24 CI Szabo (607_CR33) 1997; 60 US Khoo (607_CR13) 2000; 16 SH Ahn (607_CR2) 2007; 245 A Meindl (607_CR20) 2002; 97 |
References_xml | – volume: 20 start-page: 235 year: 2002 ident: CR11 article-title: Germline mutations of BRCA1 and BRCA2 in Korean breast and/or ovarian cancer families publication-title: Hum Mutat doi: 10.1002/humu.9059 contributor: fullname: Park – volume: 283 start-page: 2260 year: 2000 end-page: 2265 ident: CR5 article-title: Clinicopathologic features of BRCA-linked and sporadic ovarian cancer publication-title: JAMA doi: 10.1001/jama.283.17.2260 contributor: fullname: Hoskins – volume: 17 start-page: 595 year: 2007 end-page: 600 ident: CR8 article-title: Ovarian cancer incidence and survival in Korea: 1993–2002 publication-title: Int J Gynecol Cancer doi: 10.1111/j.1525-1438.2007.00824.x contributor: fullname: Lee – volume: 19 start-page: 269 year: 2004 end-page: 274 ident: CR1 article-title: Prevalence of BRCA1 and BRCA2 mutations in Korean breast cancer patients publication-title: J Korean Med Sci contributor: fullname: Son – volume: 15 start-page: 359 year: 2006 end-page: 363 ident: CR15 article-title: Breast and ovarian cancer in relatives of cancer patients, with and without BRCA mutations publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-05-0687 contributor: fullname: Whittemore – volume: 25 start-page: 415 year: 2005 end-page: 422 ident: CR19 article-title: Genomic rearrangements in the BRCA1 and BRCA2 genes publication-title: Hum Mutat doi: 10.1002/humu.20169 contributor: fullname: Mazoyer – volume: 97 start-page: 472 year: 2002 end-page: 480 ident: CR20 article-title: Comprehensive analysis of 989 patients with breast or ovarian cancer provides BRCA1 and BRCA2 mutation profiles and frequencies for the German population publication-title: Int J Cancer doi: 10.1002/ijc.1626 contributor: fullname: Meindl – volume: 106 start-page: 942 year: 2003 end-page: 945 ident: CR21 article-title: Hereditary ovarian cancer in Poland publication-title: Int J Cancer doi: 10.1002/ijc.11338 contributor: fullname: Lubinski – volume: 68 start-page: 700 year: 2001 end-page: 710 ident: CR27 article-title: Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer publication-title: Am J Hum Genet doi: 10.1086/318787 contributor: fullname: Narod – volume: 24 start-page: 350 year: 2004 ident: CR32 article-title: BRCA1 and BRCA2 germline mutations in Korean patients with sporadic breast cancer publication-title: Hum Mutat doi: 10.1002/humu.9275 contributor: fullname: Koo – volume: 99 start-page: 585 year: 2005 end-page: 590 ident: CR14 article-title: Germline mutations of BRCA1 and BRCA2 in Korean sporadic ovarian carcinoma publication-title: Gynecol Oncol doi: 10.1016/j.ygyno.2005.06.058 contributor: fullname: Kim – volume: 19 start-page: 2247 year: 2001 end-page: 2253 ident: CR18 article-title: Germline mutations in BRCA1 and BRCA2 in breast-ovarian families from a breast cancer risk evaluation clinic publication-title: J Clin Oncol contributor: fullname: Nathanson – volume: 66 start-page: 1259 year: 2000 end-page: 1272 ident: CR23 article-title: BRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer publication-title: Am J Hum Genet doi: 10.1086/302853 contributor: fullname: Narod – start-page: 1457 year: 2007 end-page: 1547 ident: CR3 publication-title: Ch 35. Ovarian and Fallopian Tube Cancer contributor: fullname: Natarajan – volume: 98 start-page: 1694 year: 2006 end-page: 1706 ident: CR28 article-title: Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada publication-title: J Natl Cancer Inst doi: 10.1093/jnci/djj465 contributor: fullname: Narod – volume: 16 start-page: 88 year: 2000 end-page: 89 ident: CR13 article-title: Mutational analysis of BRCA1 and BRCA2 genes in Chinese ovarian cancer identifies 6 novel germline mutations publication-title: Hum Mutat doi: 10.1002/1098-1004(200007)16:1<88::AID-HUMU16>3.0.CO;2-G contributor: fullname: Ozcelik – volume: 69 start-page: 28 year: 2009 end-page: 44 ident: CR29 article-title: Hereditary ovarian cancer publication-title: Crit Rev Oncol Hematol doi: 10.1016/j.critrevonc.2008.06.003 contributor: fullname: Di Fede – volume: 22 start-page: 1638 year: 2004 end-page: 1645 ident: CR7 article-title: Incidence of BRCA1 and BRCA2 mutations in young Korean breast cancer patients publication-title: J Clin Oncol doi: 10.1200/JCO.2004.04.179 contributor: fullname: Haffty – volume: 119 start-page: 2832 year: 2006 end-page: 2839 ident: CR26 article-title: Prevalence of BRCA1 and BRCA2 mutations in Pakistani breast and ovarian cancer patients publication-title: Int J Cancer doi: 10.1002/ijc.22269 contributor: fullname: Hamann – volume: 55 start-page: 318 year: 1999 end-page: 324 ident: CR35 article-title: Founder BRCA1 and BRCA2 mutations in French Canadian ovarian cancer cases unselected for family history publication-title: Clin Genet doi: 10.1034/j.1399-0004.1999.550504.x contributor: fullname: Provencher – volume: 97 start-page: 466 year: 2002 end-page: 471 ident: CR9 article-title: Association between BRCA1 and BRCA2 mutations and cancer phenotype in Spanish breast/ovarian cancer families: implications for genetic testing publication-title: Int J Cancer doi: 10.1002/ijc.1627 contributor: fullname: Caldes – volume: 20 start-page: 413 year: 2002 end-page: 424 ident: CR16 article-title: Hereditary breast and ovarian cancer in Asia: genetic epidemiology of BRCA1 and BRCA2 publication-title: Hum Mutat doi: 10.1002/humu.10154 contributor: fullname: Narod – volume: 9 start-page: 424 year: 2001 end-page: 430 ident: CR30 article-title: BRCA1 and BRCA2 mutations among 233 unselected Finnish ovarian carcinoma patients publication-title: Eur J Hum Genet doi: 10.1038/sj.ejhg.5200652 contributor: fullname: Nevanlinna – volume: 71 start-page: 595 year: 2002 end-page: 606 ident: CR17 article-title: Contribution of BRCA1 and BRCA2 mutations to breast and ovarian cancer in Pakistan publication-title: Am J Hum Genet doi: 10.1086/342506 contributor: fullname: Narod – volume: 81 start-page: 873 year: 2007 end-page: 883 ident: CR10 article-title: A systematic genetic assessment of 1, 433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes publication-title: Am J Hum Genet doi: 10.1086/521032 contributor: fullname: Goldgar – volume: 86 start-page: 737 year: 2000 end-page: 740 ident: CR36 article-title: Prevalence of founder BRCA1 and BRCA2 mutations among breast and ovarian cancer patients in Hungary publication-title: Int J Cancer doi: 10.1002/(SICI)1097-0215(20000601)86:5<737::AID-IJC21>3.0.CO;2-1 contributor: fullname: Olah – volume: 78 start-page: 148 year: 2000 end-page: 151 ident: CR34 article-title: Founder BRCA 1 and 2 mutations among a consecutive series of Ashkenazi Jewish ovarian cancer patients publication-title: Gynecol Oncol doi: 10.1006/gyno.2000.5848 contributor: fullname: Cohen – year: 2005 ident: CR24 publication-title: Clinical genetics of gynecologic cancer contributor: fullname: Narod – volume: 7 start-page: 3144 year: 2001 end-page: 3150 ident: CR31 article-title: Mutational analysis of BRCA1 and BRCA2 and clinicopathologic analysis of ovarian cancer in 82 ovarian cancer families: two common founder mutations of BRCA1 in Japanese population publication-title: Clin Cancer Res contributor: fullname: Tanaka – volume: 60 start-page: 1013 year: 1997 end-page: 1020 ident: CR33 article-title: Population genetics of BRCA1 and BRCA2 publication-title: Am J Hum Genet contributor: fullname: King – volume: 35 start-page: 3s year: 2003 ident: CR6 article-title: Distint patterns of BRCA1 and BRCA2 mutations in Korean women with early-onset breast cancer publication-title: Cancer Res Treat contributor: fullname: Haffy – volume: 104 start-page: 2807 year: 2005 end-page: 2816 ident: CR25 article-title: BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases publication-title: Cancer doi: 10.1002/cncr.21536 contributor: fullname: Sutphen – volume: 43 start-page: 42 year: 1998 end-page: 48 ident: CR12 article-title: High proportion of missense mutations of the BRCA1 and BRCA2 genes in Japanese breast cancer families publication-title: J Hum Genet doi: 10.1007/s100380050035 contributor: fullname: Miki – volume: 245 start-page: 90 year: 2007 end-page: 95 ident: CR2 article-title: BRCA1 and BRCA2 germline mutations in Korean breast cancer patients at high risk of carrying mutations publication-title: Cancer Lett doi: 10.1016/j.canlet.2005.12.031 contributor: fullname: Cho – volume: 60 start-page: 592 year: 1989 end-page: 598 ident: CR4 article-title: Risk factors for ovarian cancer: a case-control study publication-title: Br J Cancer contributor: fullname: Smith – volume: 345 start-page: 235 year: 2001 end-page: 240 ident: CR22 article-title: Parity, oral contraceptives, and the risk of ovarian cancer among carriers and noncarriers of a BRCA1 or BRCA2 mutation publication-title: N Engl J Med doi: 10.1056/NEJM200107263450401 contributor: fullname: Piura – volume: 99 start-page: 585 year: 2005 ident: 607_CR14 publication-title: Gynecol Oncol doi: 10.1016/j.ygyno.2005.06.058 contributor: fullname: YT Kim – volume: 68 start-page: 700 year: 2001 ident: 607_CR27 publication-title: Am J Hum Genet doi: 10.1086/318787 contributor: fullname: HA Risch – volume: 19 start-page: 269 year: 2004 ident: 607_CR1 publication-title: J Korean Med Sci doi: 10.3346/jkms.2004.19.2.269 contributor: fullname: SH Ahn – volume: 35 start-page: 3s year: 2003 ident: 607_CR6 publication-title: Cancer Res Treat doi: 10.4143/crt.2003.35.1.3 contributor: fullname: DH Choi – volume: 106 start-page: 942 year: 2003 ident: 607_CR21 publication-title: Int J Cancer doi: 10.1002/ijc.11338 contributor: fullname: J Menkiszak – volume: 17 start-page: 595 year: 2007 ident: 607_CR8 publication-title: Int J Gynecol Cancer doi: 10.1111/j.1525-1438.2007.00824.x contributor: fullname: HH Chung – volume: 69 start-page: 28 year: 2009 ident: 607_CR29 publication-title: Crit Rev Oncol Hematol doi: 10.1016/j.critrevonc.2008.06.003 contributor: fullname: A Russo – volume: 119 start-page: 2832 year: 2006 ident: 607_CR26 publication-title: Int J Cancer doi: 10.1002/ijc.22269 contributor: fullname: MU Rashid – volume: 9 start-page: 424 year: 2001 ident: 607_CR30 publication-title: Eur J Hum Genet doi: 10.1038/sj.ejhg.5200652 contributor: fullname: L Sarantaus – volume: 55 start-page: 318 year: 1999 ident: 607_CR35 publication-title: Clin Genet doi: 10.1034/j.1399-0004.1999.550504.x contributor: fullname: PN Tonin – volume: 16 start-page: 88 year: 2000 ident: 607_CR13 publication-title: Hum Mutat doi: 10.1002/1098-1004(200007)16:1<88::AID-HUMU16>3.0.CO;2-G contributor: fullname: US Khoo – volume: 20 start-page: 413 year: 2002 ident: 607_CR16 publication-title: Hum Mutat doi: 10.1002/humu.10154 contributor: fullname: A Liede – volume: 78 start-page: 148 year: 2000 ident: 607_CR34 publication-title: Gynecol Oncol doi: 10.1006/gyno.2000.5848 contributor: fullname: DH Tobias – volume: 245 start-page: 90 year: 2007 ident: 607_CR2 publication-title: Cancer Lett doi: 10.1016/j.canlet.2005.12.031 contributor: fullname: SH Ahn – volume: 97 start-page: 466 year: 2002 ident: 607_CR9 publication-title: Int J Cancer doi: 10.1002/ijc.1627 contributor: fullname: M Hoya de la – volume: 43 start-page: 42 year: 1998 ident: 607_CR12 publication-title: J Hum Genet doi: 10.1007/s100380050035 contributor: fullname: T Katagiri – volume: 7 start-page: 3144 year: 2001 ident: 607_CR31 publication-title: Clin Cancer Res contributor: fullname: M Sekine – volume: 60 start-page: 1013 year: 1997 ident: 607_CR33 publication-title: Am J Hum Genet contributor: fullname: CI Szabo – volume-title: Clinical genetics of gynecologic cancer year: 2005 ident: 607_CR24 contributor: fullname: SA Narod – volume: 71 start-page: 595 year: 2002 ident: 607_CR17 publication-title: Am J Hum Genet doi: 10.1086/342506 contributor: fullname: A Liede – volume: 19 start-page: 2247 year: 2001 ident: 607_CR18 publication-title: J Clin Oncol doi: 10.1200/JCO.2001.19.8.2247 contributor: fullname: AM Martin – volume: 97 start-page: 472 year: 2002 ident: 607_CR20 publication-title: Int J Cancer doi: 10.1002/ijc.1626 contributor: fullname: A Meindl – volume: 104 start-page: 2807 year: 2005 ident: 607_CR25 publication-title: Cancer doi: 10.1002/cncr.21536 contributor: fullname: T Pal – volume: 60 start-page: 592 year: 1989 ident: 607_CR4 publication-title: Br J Cancer doi: 10.1038/bjc.1989.320 contributor: fullname: M Booth – volume: 25 start-page: 415 year: 2005 ident: 607_CR19 publication-title: Hum Mutat doi: 10.1002/humu.20169 contributor: fullname: S Mazoyer – volume: 345 start-page: 235 year: 2001 ident: 607_CR22 publication-title: N Engl J Med doi: 10.1056/NEJM200107263450401 contributor: fullname: B Modan – volume: 81 start-page: 873 year: 2007 ident: 607_CR10 publication-title: Am J Hum Genet doi: 10.1086/521032 contributor: fullname: DF Easton – volume: 24 start-page: 350 year: 2004 ident: 607_CR32 publication-title: Hum Mutat contributor: fullname: JH Seo – volume: 86 start-page: 737 year: 2000 ident: 607_CR36 publication-title: Int J Cancer doi: 10.1002/(SICI)1097-0215(20000601)86:5<737::AID-IJC21>3.0.CO;2-1 contributor: fullname: M Looij Van Der – volume: 283 start-page: 2260 year: 2000 ident: 607_CR5 publication-title: JAMA doi: 10.1001/jama.283.17.2260 contributor: fullname: J Boyd – volume: 20 start-page: 235 year: 2002 ident: 607_CR11 publication-title: Hum Mutat doi: 10.1002/humu.9059 contributor: fullname: HC Kang – start-page: 1457 volume-title: Ch 35. Ovarian and Fallopian Tube Cancer year: 2007 ident: 607_CR3 contributor: fullname: JS Berek – volume: 22 start-page: 1638 year: 2004 ident: 607_CR7 publication-title: J Clin Oncol doi: 10.1200/JCO.2004.04.179 contributor: fullname: DH Choi – volume: 98 start-page: 1694 year: 2006 ident: 607_CR28 publication-title: J Natl Cancer Inst doi: 10.1093/jnci/djj465 contributor: fullname: HA Risch – volume: 15 start-page: 359 year: 2006 ident: 607_CR15 publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-05-0687 contributor: fullname: JS Lee – volume: 66 start-page: 1259 year: 2000 ident: 607_CR23 publication-title: Am J Hum Genet doi: 10.1086/302853 contributor: fullname: R Moslehi |
SSID | ssj0017572 |
Score | 2.1598115 |
Snippet | Purpose To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Methods and patients... Purpose To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Methods and patients... To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Pedigree analysis and... To evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. Pedigree analysis and... PURPOSETo evaluate the proportion of Korean ovarian cancer patients with a strong family history and the genetic status in such patients. METHODS AND... |
SourceID | proquest crossref pubmed pascalfrancis springer fao |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 1593 |
SubjectTerms | Adult Aged Antineoplastic agents Asian Continental Ancestry Group - genetics Asian people Biological and medical sciences Cancer Research Female Female genital diseases Genes, BRCA1 Genes, BRCA2 Genetic testing Germ-Line Mutation Gynecology. Andrology. Obstetrics Hematology Humans Internal Medicine Medical sciences Medicine Medicine & Public Health Middle Aged Mutation Oncology Original Paper Ovarian cancer Ovarian Neoplasms - genetics Pharmacology. Drug treatments Tumors |
SummonAdditionalLinks | – databaseName: ProQuest Public Health Database dbid: 8C1 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3LbtUwEB3RIiE2iHfTQvGCFcgificrVC5UFagsgCt1Z9mOU7FoUpp7-f6OnUdV8VglUhQrGY89xz7jMwCvMUJwJaSmVeMjlbVj1HMvaBUqrSstg8nnK06_6pO1_HymzqbcnGFKq5znxDxRN31Ie-Tv0oFQRDNCv7_8RVPRqESuThU0duAuQ79MlRuq1ZLhgYEx125KijC43mJ6JjXLUUNUcJqZAZ126m6FpZ3W9SlJ0g1op3YscPE3BPoHe5qD0vFDeDChSXI0dv8juBO7x3DvdOLLn8DHD99WR4y4riHpjhNs4yIBS3KxHTn4gfzsyJceoWNH-t-4cMZrSJ5wRSbJ1eEprI8__Vid0KluAg0IjjY0CsGc994htvAuat34OjDWNmVoTaOCl57F0jhRiyaaypua8aiil8p4XNFo8Qx2u76Le0CUaOtQK14GhHbeq7rxlTKsrVqtpVJtAW9ms9nLUR7DLkLI2cYWbWyTja0oYA8Na905Tl92_Z0n0pQl_bNaF3B4y9pLYzyJ30hTFnAwm99Oo2ywi08U8Gp5isMjcR6ui_12sNogxDJKFfB87LObz0yyPFziu2_nTrxp-Z__sP_f7ziA-5ltymcVX8Du5mobXyJo2fjD7JrX9F3iVg priority: 102 providerName: ProQuest |
Title | BRCA1 and BRCA2 germline mutations in Korean ovarian cancer patients |
URI | https://link.springer.com/article/10.1007/s00432-009-0607-3 https://www.ncbi.nlm.nih.gov/pubmed/19499246 https://www.proquest.com/docview/220509936 https://search.proquest.com/docview/67658755 |
Volume | 135 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Nb9MwGH61dhLiwjcsDIoPnECp6ji2k2NXOiamTWhQqZws23EQmpZMS7sDv57Xzsc0bRx2iaMktmK__njsx-9jgI84QiScpSLOCuPiNNc0NolhcWYzITKRWhn8K05OxdEq_bbm6x1IhqWL6nzaM5Khox583YJ4XBzW8oVfWxvBLvd6X2PYnX_9dbwcuAPJw5FNXggGp1lU9FzmfYncGo1Gpa793kjdYPGU7bkW9wHPO6RpGIsOn7b-gU2QMPRbUM6n242Z2r93BR4fkM1n8KSDpmTe1qXnsOOqF_DopCPfX8KXg7PFnBJdFcTfJQRTvfAolVxsW0K_IX8qclwjDq1IfY2zcAytr1ZXpNNvbV7B6nD5c3EUd4cwxBaR1iZ2jFFtjNEIVIx2QhQmt5SWxcyWsuDWpIa6mdQsZ4WTmZE5TRx3JuXS4PRIsNcwrurK7QHhrMxtzpOZRZxoDM8Lk3FJy6wUIuW8jOBTbwx12WptqEFVOZSLwnJRvlwUi2APzaX0b-wL1epH4hlY6sXUchHB5JYNh8QSr6STylkE-71RVddkG-U9jhEuM4z-YXiLbc0TKLpy9bZRQiJek5xH8KatCTe_6TV-khTjfu7NepPyf_Pw9kFf78PjQGUFR8h3MN5cbd17REQbM4GRXEu8Zgs66ZoDhgfL0-9n-HSVzP8B7Ov_fg |
link.rule.ids | 315,786,790,12083,12250,21416,27955,27956,31752,31753,33299,33300,33777,33778,41114,41556,42183,42625,43343,43612,43838,52144,52267,74100,74369,74657 |
linkProvider | Springer Nature |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT9wwEB4VKrW9oL4JtOBDT62ixvErOVUUiraF5dCy0t4s23FQDySU7PL7GTsPhGh7SqQoVjIee77xZ38D8AEjRC4Yl2lRWZ_y0tDU5palhSukLCR3Kp6vmJ_J2YL_WIrlsDenG7ZVjnNinKir1oU18s_hQCiiGSa_XP1JQ9GoQK4OFTQ24DFnjAc3V8sp38LAGGs3BUUYzLeoHEnNrNcQZXkamQEZVuruhaWN2rRhk6Tp0E51X-Dibwj0AXsag9Lxc9ga0CQ56Lv_BTzyzUt4Mh_48ldw9PXn4QElpqlIuMsJtnEZgCW5XPccfEd-N-SkRejYkPYGE2e8uuAJ12SQXO1ew-L42_nhLB3qJqQOwdEq9YxRY601iC2s8VJWtnSU1lXmalUJZ7mlPlOGlazyqrCqpLkX3nKhLGY0kr2BzaZt_DYQwerSlSLPHEI7a0VZ2UIoWhe1lFyIOoGPo9n0VS-PoSch5GhjjTbWwcaaJbCNhtXmAqcvvfiVB9KUBv2zUiawd8_aU2N5EL_hKktgdzS_HkZZpyefSGB_eorDI3AepvHtutNSIcRSQiTwtu-zu88Msjw5x3c_jZ141_I__2Hnv9-xD09n5_NTffr97GQXnkXmKZ5bfAebq-u1f48AZmX3opveAgxl5Xs |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3LTtwwFL0qIKFuqr5JacGLrlpFxPErWVW8RrSUEaIdiZ1lOw7qgoSSGb6f68QJQn2sEimKlRxf28c-9rkAH3GEyAXjMi0q61NeGpra3LK0cIWUheRO9ecrzubyZMG_XYrLaCnUxW2VY5_Yd9RV68Ia-V44EIpshsm9Ou6KOD-afbn5nYYEUkFojdk01mBDcSlwHrZxcDw_v5gkBSX6TE7BHwZnX1SOEmc2OIqyPO11AhnW7R4NUmu1acOWSdMhavWQ7uJvfPQPLbUfombP4VnklmR_CIYX8MQ3L2HzLKrnr-Do4OJwnxLTVCTc5QTLuA40k1yvBkW-I78actoikWxIe4fTaLy6EBe3JBqwdq9hMTv-eXiSxiwKqUOqtEw9Y9RYaw0yDWu8lJUtHaV1lblaVcJZbqnPlGElq7wqrCpp7oW3XCiL8xvJ3sB60zZ-C4hgdelKkWcOiZ61oqxsIRSti1pKLkSdwKcRNn0zmGXoyRa5x1gjxjpgrFkCWwisNlfYmenFjzxIqDS4oZUygZ1HaE-F5cEKh6ssge0Rfh3bXKenCElgd3qKjSUoIKbx7arTUiHhUkIk8Haos4fPDCY9Ocd3P4-V-FDyP__h3X-_Yxc2MUb196_z02142stQ_SHG97C-vF35D8hmlnYnxuk9RbHrHg |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=BRCA1+and+BRCA2+germline+mutations+in+Korean+ovarian+cancer+patients&rft.jtitle=Journal+of+cancer+research+and+clinical+oncology&rft.au=Lim%2C+Myong+Cheol&rft.au=Kang%2C+Sokbom&rft.au=Seo%2C+Sang-Soo&rft.au=Kong%2C+Sun-Young&rft.date=2009-11-01&rft.issn=0171-5216&rft.eissn=1432-1335&rft.volume=135&rft.issue=11&rft.spage=1593&rft.epage=1599&rft_id=info:doi/10.1007%2Fs00432-009-0607-3&rft.externalDBID=n%2Fa&rft.externalDocID=10_1007_s00432_009_0607_3 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0171-5216&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0171-5216&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0171-5216&client=summon |