Thromboelastography characterized CD36 null subjects as slow clot formation and indicative of hypocoagulability

• Published in: Thrombosis research Vol. 178; pp. 79 - 84
• Main Authors: Lee, Bai-Chin, Lin, Kuan-Hsiao, Hu, Chung-Yi, Lo, Shyh-Chyi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.06.2019
• Subjects: Adult; Blood Coagulation - genetics; CD36; CD36 Antigens - metabolism; Female; Humans; Male; Middle Aged; Platelet Aggregation - genetics; Platelet–monocyte aggregate (PMA); Thrombelastography - methods; Thromboelastography (TEG); MA; Thromboelastography (TEG); PMA; LDL; CI; TEG; TMA; Platelet–monocyte aggregate (PMA); CD36; R time; PRP

Platelet CD36 is the receptor for oxidized low-density lipoprotein and collagen. The conventional platelet test cannot distinguish CD36-null subjects from normal expression subjects. Thromboelastography (TEG) testing can analyze global hemostasis. TEG testing data on CD36-null subjects are not avail...