Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein

• Published in: Experimental gerontology Vol. 41; no. 2; pp. 215 - 219
• Main Authors: Paddon-Jones, Douglas, Sheffield-Moore, Melinda, Katsanos, Christos S., Zhang, Xiao-Jun, Wolfe, Robert R.
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.02.2006
• Subjects: Administration, Oral; Aged; Aging; Aging - physiology; Amino Acids - administration & dosage; Amino Acids - analysis; Amino Acids - metabolism; Analysis of Variance; Female; Humans; Leg - blood supply; Male; Metabolism; Milk Proteins - administration & dosage; Milk Proteins - chemistry; Milk Proteins - metabolism; Muscle Proteins - biosynthesis; Nutrition; Phenylalanine - analysis; Phenylalanine - blood; Regional Blood Flow; Sarcopenia; Supplements; Whey Proteins; Aging; Sarcopenia; Nutrition; Metabolism; Supplements

To counteract the debilitating progression of sarcopenia, a protein supplement should provide an energetically efficient anabolic stimulus. We quantified net muscle protein synthesis in healthy elderly individuals (65–79 yrs) following ingestion of an isocaloric intact whey protein supplement (WY; n...