Visual Detection of Ascorbic Acid via Smartphone with Portable Probe Based on Assembled FePO4@GO Peroxidase-like Nanozyme

Ascorbic acid (AA) plays an important role in many physiological and biochemical processes. Adequate quantification of AA is required for controlling the intake of AA for health management. In this study, a portable probe was fabricated based on the assembled FePO4@GO nanozyme by homogeneous precipi...

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Published inMolecules (Basel, Switzerland) Vol. 29; no. 21; p. 5097
Main Authors Zhang, Zifang, Bai, Junhua, Gong, Yan, Zhang, Lifang
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 29.10.2024
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Abstract Ascorbic acid (AA) plays an important role in many physiological and biochemical processes. Adequate quantification of AA is required for controlling the intake of AA for health management. In this study, a portable probe was fabricated based on the assembled FePO4@GO nanozyme by homogeneous precipitation. FePO4@GO exhibits excellent peroxidase (POD) activity. As an efficient free radical scavenger, ascorbic acid scavenges 1O2 free radicals produced by hydrogen peroxide catalyzed by peroxidase enzymes and then inhibits the color reaction of 3,3′,5,5′-tetramethylbenzidine (TMB). A good linear relationship between the color of the reaction system and the concentration of AA in the range of 2.5–75 μM was presented, and the detection limit is 1.25 μM. Furthermore, a visual colorimetric detection platform was constructed using a smartphone. The AA content is accurately reflected by intelligent recognition of color changes in the reaction system. It provides an alternative approach for portable and visual rapid detection of Vitamin C (VC) in medicine. Meanwhile, it also provides a reference for the assembly of an intelligent detection platform based on nanozymes.
AbstractList Ascorbic acid (AA) plays an important role in many physiological and biochemical processes. Adequate quantification of AA is required for controlling the intake of AA for health management. In this study, a portable probe was fabricated based on the assembled FePO4@GO nanozyme by homogeneous precipitation. FePO4@GO exhibits excellent peroxidase (POD) activity. As an efficient free radical scavenger, ascorbic acid scavenges 1O2 free radicals produced by hydrogen peroxide catalyzed by peroxidase enzymes and then inhibits the color reaction of 3,3′,5,5′-tetramethylbenzidine (TMB). A good linear relationship between the color of the reaction system and the concentration of AA in the range of 2.5–75 μM was presented, and the detection limit is 1.25 μM. Furthermore, a visual colorimetric detection platform was constructed using a smartphone. The AA content is accurately reflected by intelligent recognition of color changes in the reaction system. It provides an alternative approach for portable and visual rapid detection of Vitamin C (VC) in medicine. Meanwhile, it also provides a reference for the assembly of an intelligent detection platform based on nanozymes.
Ascorbic acid (AA) plays an important role in many physiological and biochemical processes. Adequate quantification of AA is required for controlling the intake of AA for health management. In this study, a portable probe was fabricated based on the assembled FePO4@GO nanozyme by homogeneous precipitation. FePO4@GO exhibits excellent peroxidase (POD) activity. As an efficient free radical scavenger, ascorbic acid scavenges 1O2 free radicals produced by hydrogen peroxide catalyzed by peroxidase enzymes and then inhibits the color reaction of 3,3',5,5'-tetramethylbenzidine (TMB). A good linear relationship between the color of the reaction system and the concentration of AA in the range of 2.5-75 μM was presented, and the detection limit is 1.25 μM. Furthermore, a visual colorimetric detection platform was constructed using a smartphone. The AA content is accurately reflected by intelligent recognition of color changes in the reaction system. It provides an alternative approach for portable and visual rapid detection of Vitamin C (VC) in medicine. Meanwhile, it also provides a reference for the assembly of an intelligent detection platform based on nanozymes.Ascorbic acid (AA) plays an important role in many physiological and biochemical processes. Adequate quantification of AA is required for controlling the intake of AA for health management. In this study, a portable probe was fabricated based on the assembled FePO4@GO nanozyme by homogeneous precipitation. FePO4@GO exhibits excellent peroxidase (POD) activity. As an efficient free radical scavenger, ascorbic acid scavenges 1O2 free radicals produced by hydrogen peroxide catalyzed by peroxidase enzymes and then inhibits the color reaction of 3,3',5,5'-tetramethylbenzidine (TMB). A good linear relationship between the color of the reaction system and the concentration of AA in the range of 2.5-75 μM was presented, and the detection limit is 1.25 μM. Furthermore, a visual colorimetric detection platform was constructed using a smartphone. The AA content is accurately reflected by intelligent recognition of color changes in the reaction system. It provides an alternative approach for portable and visual rapid detection of Vitamin C (VC) in medicine. Meanwhile, it also provides a reference for the assembly of an intelligent detection platform based on nanozymes.
Ascorbic acid (AA) plays an important role in many physiological and biochemical processes. Adequate quantification of AA is required for controlling the intake of AA for health management. In this study, a portable probe was fabricated based on the assembled FePO 4 @GO nanozyme by homogeneous precipitation. FePO 4 @GO exhibits excellent peroxidase (POD) activity. As an efficient free radical scavenger, ascorbic acid scavenges 1 O 2 free radicals produced by hydrogen peroxide catalyzed by peroxidase enzymes and then inhibits the color reaction of 3,3′,5,5′-tetramethylbenzidine (TMB). A good linear relationship between the color of the reaction system and the concentration of AA in the range of 2.5–75 μM was presented, and the detection limit is 1.25 μM. Furthermore, a visual colorimetric detection platform was constructed using a smartphone. The AA content is accurately reflected by intelligent recognition of color changes in the reaction system. It provides an alternative approach for portable and visual rapid detection of Vitamin C (VC) in medicine. Meanwhile, it also provides a reference for the assembly of an intelligent detection platform based on nanozymes.
Author Gong, Yan
Zhang, Zifang
Zhang, Lifang
Bai, Junhua
AuthorAffiliation 1 School of Chemistry and Materials Science, Shanxi Normal University, Taiyuan 030031, China
3 Collaborative Innovation Center for Shanxi Advanced Permanent Magnetic Materials and Technology, Taiyuan 030031, China
2 School of Life Science, Shanxi Normal University, Taiyuan 030031, China
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Cites_doi 10.1002/chem.201303051
10.1038/s41596-018-0001-1
10.1016/j.jwpe.2021.102265
10.1002/adfm.202110432
10.1016/j.bios.2017.01.061
10.1021/ar020152u
10.1016/j.snb.2019.127106
10.1016/j.carbon.2013.04.058
10.1016/j.jallcom.2019.04.268
10.1016/j.cej.2023.143615
10.1016/j.bios.2021.113686
10.1016/j.cej.2020.125574
10.1016/j.ceramint.2018.01.176
10.1016/j.cej.2019.03.243
10.1016/j.bios.2020.112342
10.1021/ac900136z
10.1021/ja01539a017
10.1002/chem.201705980
10.1016/j.electacta.2011.08.084
10.1016/j.cej.2022.137855
10.1007/s00604-018-2691-z
10.1038/nnano.2007.260
10.1002/adfm.201001391
10.1016/j.bios.2011.03.013
10.1016/j.cej.2021.134414
10.1002/chem.201404960
10.1021/nn901221k
10.1016/j.jcis.2015.02.005
10.1021/acs.chemrev.8b00672
10.1016/j.foodchem.2022.135017
10.1039/C9RA03850G
10.1021/cr020443g
10.1016/j.foodchem.2023.137750
10.1021/acs.analchem.3c01005
10.1021/jacs.0c12605
10.1021/nn901311t
10.1002/adma.200903783
10.1016/j.foodchem.2018.03.032
10.1016/j.ceramint.2016.04.017
10.1016/j.jpcs.2023.111243
10.1016/j.bios.2016.05.087
10.1039/c2nr12109c
10.1016/j.matchemphys.2022.126561
10.1016/j.snb.2021.131131
10.1016/j.electacta.2019.135135
10.1016/j.synthmet.2019.116105
10.1016/j.ccr.2021.214170
10.1016/j.jece.2019.102990
10.1016/j.snb.2023.133422
10.1039/C6TB00422A
10.1002/adfm.201603716
10.1021/nn102767d
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References ref_14
ref_13
Zhou (ref_18) 2009; 81
ref_10
Cao (ref_28) 2024; 436
Lu (ref_34) 2016; 42
Fong (ref_52) 2016; 85
Du (ref_24) 2011; 5
Luo (ref_30) 2018; 258
ref_15
Dong (ref_22) 2012; 4
Jampaiah (ref_49) 2016; 4
Gao (ref_6) 2007; 2
Genet (ref_4) 2003; 36
Xi (ref_47) 2021; 143
ref_20
Tan (ref_50) 2014; 20
ref_29
Meunier (ref_5) 2004; 104
Qu (ref_17) 2011; 26
Chen (ref_31) 2017; 91
Zhang (ref_38) 2016; 26
ref_36
ref_35
ref_32
Weng (ref_51) 2011; 56
Wang (ref_16) 2018; 185
Guo (ref_33) 2013; 60
ref_39
Fu (ref_2) 2023; 95
Zhang (ref_25) 2010; 4
Liu (ref_21) 2010; 20
Chen (ref_19) 2010; 4
Zhou (ref_23) 2018; 44
ref_45
Zhang (ref_37) 2019; 795
ref_43
ref_42
Guo (ref_12) 2015; 448
ref_41
ref_40
Huang (ref_1) 2019; 119
Song (ref_26) 2010; 22
Jia (ref_27) 2019; 9
Jiang (ref_3) 2018; 13
Ma (ref_11) 2019; 370
ref_9
ref_8
Ai (ref_48) 2013; 19
Liu (ref_46) 2018; 24
ref_7
Hummers (ref_44) 1958; 80
References_xml – volume: 19
  start-page: 15105
  year: 2013
  ident: ref_48
  article-title: MIL-53(Fe): A Metal–Organic Framework with Intrinsic Peroxidase-Like Catalytic Activity for Colorimetric Biosensing
  publication-title: Chem.–A Eur. J.
  doi: 10.1002/chem.201303051
– volume: 13
  start-page: 1506
  year: 2018
  ident: ref_3
  article-title: Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes
  publication-title: Nat. Protoc.
  doi: 10.1038/s41596-018-0001-1
– ident: ref_15
  doi: 10.1016/j.jwpe.2021.102265
– ident: ref_7
  doi: 10.1002/adfm.202110432
– volume: 91
  start-page: 878
  year: 2017
  ident: ref_31
  article-title: Nitrogen doped graphene quantum dots based long-persistent chemiluminescence system for ascorbic acid imaging
  publication-title: Biosens. Bioelectron.
  doi: 10.1016/j.bios.2017.01.061
– volume: 36
  start-page: 908
  year: 2003
  ident: ref_4
  article-title: Asymmetric Catalytic Hydrogenation. Design of New Ru Catalysts and Chiral Ligands:  From Laboratory to Industrial Applications
  publication-title: Acc. Chem. Res.
  doi: 10.1021/ar020152u
– ident: ref_41
  doi: 10.1016/j.snb.2019.127106
– volume: 60
  start-page: 437
  year: 2013
  ident: ref_33
  article-title: Graphene oxide–Fe2O3 hybrid material as highly efficient heterogeneous catalyst for degradation of organic contaminants
  publication-title: Carbon
  doi: 10.1016/j.carbon.2013.04.058
– volume: 795
  start-page: 34
  year: 2019
  ident: ref_37
  article-title: Bowl-like double carbon layer architecture of hollow carbon@FePO4@reduced graphene oxide composite as high-performance cathodes for sodium and lithium ion batteries
  publication-title: J. Alloys Compd.
  doi: 10.1016/j.jallcom.2019.04.268
– ident: ref_40
  doi: 10.1016/j.cej.2023.143615
– ident: ref_9
  doi: 10.1016/j.bios.2021.113686
– ident: ref_14
  doi: 10.1016/j.cej.2020.125574
– volume: 44
  start-page: 7240
  year: 2018
  ident: ref_23
  article-title: Graphene oxide-FePO4 nanocomposite: Synthesis, characterization and photocatalytic properties as a Fenton-like catalyst
  publication-title: Ceram. Int.
  doi: 10.1016/j.ceramint.2018.01.176
– volume: 370
  start-page: 938
  year: 2019
  ident: ref_11
  article-title: Mesoporous amorphous FePO4 nanosphere@Graphene as a faradic electrode in capacitive deionization for high-capacity and fast removal of NaCl from water
  publication-title: Chem. Eng. J.
  doi: 10.1016/j.cej.2019.03.243
– ident: ref_45
  doi: 10.1016/j.bios.2020.112342
– volume: 81
  start-page: 5603
  year: 2009
  ident: ref_18
  article-title: Electrochemical Sensing and Biosensing Platform Based on Chemically Reduced Graphene Oxide
  publication-title: Anal. Chem.
  doi: 10.1021/ac900136z
– volume: 80
  start-page: 1339
  year: 1958
  ident: ref_44
  article-title: Preparation of Graphitic Oxide
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja01539a017
– volume: 24
  start-page: 6148
  year: 2018
  ident: ref_46
  article-title: Fluorescein as a Visible-Light-Induced Oxidase Mimic for Signal-Amplified Colorimetric Assay of Carboxylesterase by an Enzymatic Cascade Reaction
  publication-title: Chem.—A Eur. J.
  doi: 10.1002/chem.201705980
– volume: 56
  start-page: 9937
  year: 2011
  ident: ref_51
  article-title: A highly sensitive ascorbic acid sensor using a Ni–Pt electrode
  publication-title: Electrochim. Acta
  doi: 10.1016/j.electacta.2011.08.084
– ident: ref_43
  doi: 10.1016/j.cej.2022.137855
– volume: 185
  start-page: 140
  year: 2018
  ident: ref_16
  article-title: FePO4 embedded in nanofibers consisting of amorphous carbon and reduced graphene oxide as an enzyme mimetic for monitoring superoxide anions released by living cells
  publication-title: Microchim. Acta
  doi: 10.1007/s00604-018-2691-z
– volume: 2
  start-page: 577
  year: 2007
  ident: ref_6
  article-title: Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
  publication-title: Nat. Nanotechnol.
  doi: 10.1038/nnano.2007.260
– volume: 20
  start-page: 4175
  year: 2010
  ident: ref_21
  article-title: Self-Assembling TiO2 Nanorods on Large Graphene Oxide Sheets at a Two-Phase Interface and Their Anti-Recombination in Photocatalytic Applications
  publication-title: Adv. Funct. Mater.
  doi: 10.1002/adfm.201001391
– volume: 26
  start-page: 3927
  year: 2011
  ident: ref_17
  article-title: Colorimetric platform for visual detection of cancer biomarker based on intrinsic peroxidase activity of graphene oxide
  publication-title: Biosens. Bioelectron.
  doi: 10.1016/j.bios.2011.03.013
– ident: ref_42
  doi: 10.1016/j.cej.2021.134414
– volume: 20
  start-page: 16377
  year: 2014
  ident: ref_50
  article-title: Metal–Organic Framework-Derived Copper Nanoparticle@Carbon Nanocomposites as Peroxidase Mimics for Colorimetric Sensing of Ascorbic Acid
  publication-title: Chem.–A Eur. J.
  doi: 10.1002/chem.201404960
– volume: 4
  start-page: 380
  year: 2010
  ident: ref_25
  article-title: P25-Graphene Composite as a High Performance Photocatalyst
  publication-title: ACS Nano
  doi: 10.1021/nn901221k
– volume: 448
  start-page: 460
  year: 2015
  ident: ref_12
  article-title: Enhanced photo-Fenton degradation of rhodamine B using graphene oxide–amorphous FePO4 as effective and stable heterogeneous catalyst
  publication-title: J. Colloid Interface Sci.
  doi: 10.1016/j.jcis.2015.02.005
– volume: 119
  start-page: 4357
  year: 2019
  ident: ref_1
  article-title: Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
  publication-title: Chem. Rev.
  doi: 10.1021/acs.chemrev.8b00672
– ident: ref_29
  doi: 10.1016/j.foodchem.2022.135017
– volume: 9
  start-page: 26843
  year: 2019
  ident: ref_27
  article-title: The fabrication of an Ni6MnO8 nanoflake-modified acupuncture needle electrode for highly sensitive ascorbic acid detection
  publication-title: RSC Adv.
  doi: 10.1039/C9RA03850G
– volume: 104
  start-page: 3947
  year: 2004
  ident: ref_5
  article-title: Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
  publication-title: Chem. Rev.
  doi: 10.1021/cr020443g
– volume: 436
  start-page: 137750
  year: 2024
  ident: ref_28
  article-title: Hierarchical N-doped porous carbon scaffold Cu/Co-oxide with enhanced electrochemical sensing properties for the detection of glucose in beverages and ascorbic acid in vitamin C tablets
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2023.137750
– volume: 95
  start-page: 10844
  year: 2023
  ident: ref_2
  article-title: Research Progress in Iron-Based Nanozymes: Catalytic Mechanisms, Classification, and Biomedical Applications
  publication-title: Anal. Chem.
  doi: 10.1021/acs.analchem.3c01005
– volume: 143
  start-page: 2660
  year: 2021
  ident: ref_47
  article-title: Nickel–Platinum Nanoparticles as Peroxidase Mimics with a Record High Catalytic Efficiency
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/jacs.0c12605
– volume: 4
  start-page: 2822
  year: 2010
  ident: ref_19
  article-title: Graphene Oxide−MnO2 Nanocomposites for Supercapacitors
  publication-title: ACS Nano
  doi: 10.1021/nn901311t
– volume: 22
  start-page: 2206
  year: 2010
  ident: ref_26
  article-title: Graphene Oxide: Intrinsic Peroxidase Catalytic Activity and Its Application to Glucose Detection
  publication-title: Adv. Mater.
  doi: 10.1002/adma.200903783
– volume: 258
  start-page: 214
  year: 2018
  ident: ref_30
  article-title: N,S co-doped carbon dots based fluorescent “on-off-on” sensor for determination of ascorbic acid in common fruits
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2018.03.032
– volume: 42
  start-page: 11482
  year: 2016
  ident: ref_34
  article-title: Synthesis of sulfur/FePO4/graphene oxide nanocomposites for lithium–sulfur batteries
  publication-title: Ceram. Int.
  doi: 10.1016/j.ceramint.2016.04.017
– ident: ref_39
  doi: 10.1016/j.jpcs.2023.111243
– volume: 85
  start-page: 844
  year: 2016
  ident: ref_52
  article-title: A unique “turn-on” fluorescence signalling strategy for highly specific detection of ascorbic acid using carbon dots as sensing probe
  publication-title: Biosens. Bioelectron.
  doi: 10.1016/j.bios.2016.05.087
– volume: 4
  start-page: 3969
  year: 2012
  ident: ref_22
  article-title: Graphene oxide–Fe3O4 magnetic nanocomposites with peroxidase-like activity for colorimetric detection of glucose
  publication-title: Nanoscale
  doi: 10.1039/c2nr12109c
– ident: ref_13
  doi: 10.1016/j.matchemphys.2022.126561
– ident: ref_10
  doi: 10.1016/j.snb.2021.131131
– ident: ref_35
  doi: 10.1016/j.electacta.2019.135135
– ident: ref_36
  doi: 10.1016/j.synthmet.2019.116105
– ident: ref_8
  doi: 10.1016/j.ccr.2021.214170
– ident: ref_20
  doi: 10.1016/j.jece.2019.102990
– ident: ref_32
  doi: 10.1016/j.snb.2023.133422
– volume: 4
  start-page: 3874
  year: 2016
  ident: ref_49
  article-title: Fe-doped CeO2 nanorods for enhanced peroxidase-like activity and their application towards glucose detection
  publication-title: J. Mater. Chem. B
  doi: 10.1039/C6TB00422A
– volume: 26
  start-page: 7754
  year: 2016
  ident: ref_38
  article-title: Nitrogen-Doped Graphene Ribbon Assembled Core–Sheath MnO@Graphene Scrolls as Hierarchically Ordered 3D Porous Electrodes for Fast and Durable Lithium Storage
  publication-title: Adv. Funct. Mater.
  doi: 10.1002/adfm.201603716
– volume: 5
  start-page: 590
  year: 2011
  ident: ref_24
  article-title: Hierarchically Ordered Macro−Mesoporous TiO2−Graphene Composite Films: Improved Mass Transfer, Reduced Charge Recombination, and Their Enhanced Photocatalytic Activities
  publication-title: ACS Nano
  doi: 10.1021/nn102767d
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Snippet Ascorbic acid (AA) plays an important role in many physiological and biochemical processes. Adequate quantification of AA is required for controlling the...
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SubjectTerms ascorbic acid
Biocompatibility
Composite materials
Environmental protection
Enzyme kinetics
FePO4@GO nanozymes
Nanomaterials
Nanoparticles
Oxidation
peroxidase-like nanozymes
Smartphones
Spectrum analysis
visual detection
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Title Visual Detection of Ascorbic Acid via Smartphone with Portable Probe Based on Assembled FePO4@GO Peroxidase-like Nanozyme
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https://pubmed.ncbi.nlm.nih.gov/PMC11547973
https://doaj.org/article/a49704323cbd40609fe38eb721745abe
Volume 29
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