Cooling of cilia allows functional analysis of the beat pattern for diagnostic testing

• Published in: Chest Vol. 140; no. 1; p. 186
• Main Authors: Smith, Claire M, Hirst, Robert A, Bankart, Michael J, Jones, David W, Easton, Andrew J, Andrew, Peter W, O'Callaghan, Christopher
• Format: Journal Article
• Language: English
• Published: United States 01.07.2011
• Subjects: Adolescent; Adult; Biopsy; Child; Child, Preschool; Cilia - physiology; Cilia - ultrastructure; Cold Temperature; Female; Follow-Up Studies; Humans; Infant; Male; Microscopy, Video; Mucociliary Clearance - physiology; Nasal Mucosa - cytology; Nasal Mucosa - metabolism; Reproducibility of Results; Respiratory Tract Diseases - diagnosis; Young Adult

Reports of the effect of low temperatures on ciliary beat frequency (CBF) are conflicting, and the effect on ciliary beat pattern has not been reported. We aimed to clarify this association and determine whether cooling of cilia may allow ciliary function to be assessed without the need of expensive...