Dual-channel nanoelectrochemical sensor for monitoring intracellular ROS and NADH kinetic variations of their concentrations

• Published in: Biosensors & bioelectronics Vol. 222; no. 22; p. 114928
• Main Authors: Jiao, Yu-Ting, Jiang, Hong, Wu, Wen-Tao, Qi, Yu-Ting, Wen, Ming-Yong, Yang, Xiao-Ke, Kang, Yi-Ran, Zhang, Xin-Wei, Amatore, Christian, Huang, Wei-Hua
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.02.2023; Elsevier
• Subjects: Analytical chemistry; Biosensing Techniques; biosensors; Chemical Sciences; Dual-channel nanowire electrode; electrodes; inflammation; Intracellular analysis; Kinetics; mechanism of action; Metal Nanoparticles; mitochondria; NAD (coenzyme); NAD - chemistry; NADH; nanoparticles; nanowires; Oxidation-Reduction; Platinum; polymers; Reactive Oxygen Species; Resveratrol; ROS; Simultaneous detection; species; Intracellular analysis; NADH; Simultaneous detection; Dual-channel nanowire electrode; ROS

Reactive oxygen species (ROS) and nicotinamide adenine dinucleotide (NADH) are important intracellular redox-active molecules involved in various pathological processes including inflammation, neurodegenerative diseases, and cancer. However, the fast dynamic changes and mutual regulatory kinetic rel...