Gene Filtering in the Analysis of Illumina Microarray Experiments

• Published in: Statistical applications in genetics and molecular biology Vol. 11; no. 2
• Main Authors: Forcheh, Anyiawung Chiara, Verbeke, Geert, Kasim, Adetayo, Lin, Dan, Shkedy, Ziv, Talloen, Willem, Göhlmann, Hinrich WH, Clement, Lieven
• Format: Journal Article
• Language: English
• Published: Germany De Gruyter 06.01.2012
• Subjects: Computational Biology - methods; Gene Expression Profiling - methods; gene filtering; High-Throughput Nucleotide Sequencing; illumina bead arrays; linear mixed model; Models, Statistical; Oligonucleotide Array Sequence Analysis

Illumina bead arrays are microarrays that contain a random number of technical replicates (beads) for every probe (bead type) within the same array. Typically around 30 beads are placed at random positions on the array surface, which opens unique opportunities for quality control. Most preprocessing...