Importance of plasma fibronectin in determining PFP and PRP clot mechanical properties

• Published in: Thrombosis research Vol. 29; no. 2; pp. 243 - 248
• Main Authors: Chow, Thomas W., McIntire, Larry V., Peterson, Dolores M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.01.1983
• Subjects: Biophysical Phenomena; Biophysics; Blood Coagulation; fibrinogen; Fibrinogen - analysis; fibronectin; Fibronectins - blood; Fibronectins - physiology; Humans; Plasma - analysis; Plasma - physiology; Plasma clot structure; Platelet Count; Plasma clot structure; fibronectin; fibrinogen

Plasma fibronectin has been shown to be incorporated into fibrin clots. The serum concentration of fibronectin is 20-50% lower than the plasma concentration (1). Grinnell and Feld, using an indirect immunofluorescence analysis on blood clots prepared on plastic strata, demonstrated that the fibrin-p...