Small‐molecule nanoprodrug with high drug loading and EGFR, PI3K/AKT dual‐inhibiting properties for bladder cancer treatment - Li, Guoyin; Song, Zewen; Ru, Yi; Zhang, Jing; Luo, Lianxiang; Yang, Wei; Wu, Hao; Jin, Haibao; Bao, Xuanwen; Wei, Di; Yan, Zhao; Qu, Haijing; et al. (Exploration (Beijing, China), 2023)
Keywords: 1-Phosphatidylinositol 3-kinase; AKT protein; Apoptosis; Biocompatibility; Bladder; Bladder cancer; Cancer; Cancer therapies; Cell cycle; Chemotherapy; Epidermal growth factor; epidermal growth factor receptor (EGFR); Epidermal growth factor receptors; Genes; Growth factors; Hesperidin; high drug loading; In vivo methods and tests; Kinases; Malignancy; Nanoparticles; Natural products; NMR; Nuclear magnetic resonance; Proteins; Receptors; Self-assembly; Software; Solvents; Succinic acid; Survival; Toxicity; Triptolide; Tyrosine; triptolide; epidermal growth factor receptor (EGFR); bladder cancer; high drug loading; hesperidin