Efficacy of intensive orbitofrontal continuous Theta Burst Stimulation (iOFcTBS) in Obsessive Compulsive Disorder: A Randomized Placebo Controlled Study

• Published in: Psychiatry research Vol. 298; p. 113784
• Main Authors: Dutta, Parth, Dhyani, Mohan, Garg, Shobit, Tikka, Sai Krishna, Khattri, Sumit, Mehta, Sumit, Mishra, Jyoti
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.04.2021
• Subjects: Anxiety; Depression; Magnetic Stimulation; OCD; Orbito-frontal cortex; Randomization; Orbito-frontal cortex; Magnetic Stimulation; OCD; Depression; Randomization; Anxiety

•Hyper-connectivity of Orbitofrontalcortex (OFC) with striatum is common in OCD.•Theta burst stimulation (TBS) is a stronger and quicker treatment option.•Inhibitory cTBS can be given as an ‘Intensive protocol’ in OCD.•cTBS targeted over OFC is safe, well tolerated, and results in global improvement...