Screening of Lactobacillus plantarum subsp. plantarum with Potential Probiotic Activities for Inhibiting ETEC K88 in Weaned Piglets

• Published in: Molecules (Basel, Switzerland) Vol. 25; no. 19; p. 4481
• Main Authors: Wang, Weiwei, Ma, Hao, Yu, Haojie, Qin, Guangyong, Tan, Zhongfang, Wang, Yanping, Pang, Huili
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 29.09.2020; MDPI
• Subjects: Acids - metabolism; Animals; Antibiotics; antimicrobial; Antimicrobial agents; Bacteria; Bile Acids and Salts - metabolism; Biomass; Carbohydrates - chemistry; Cell Line; Cell Membrane - drug effects; Cell Membrane - metabolism; Cell Survival - drug effects; Diarrhea; Drug resistance; E coli; Enterotoxigenic Escherichia coli - drug effects; ETEC K88; Fermentation - drug effects; Gastrointestinal Tract - microbiology; Hemolysis - drug effects; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; L. plantarum subsp. plantarum; Lactobacillus - chemistry; Lactobacillus - genetics; Lactobacillus - growth & development; Lactobacillus - isolation & purification; Microbial Sensitivity Tests; Microbial Viability - drug effects; Mortality; Penicillin; Phylogenetics; Phylogeny; Physiology; Probiotics; Probiotics - pharmacology; Production capacity; RNA, Ribosomal, 16S - genetics; Swine; Toxicity Tests; Virulence Factors - genetics; Weaning; Zinc oxides; United States > US; China; antimicrobial; ETEC K88; L. plantarum subsp. plantarum; probiotics

For screening excellent lactic acid bacteria (LAB) strains to inhibit enterotoxigenic Escherichia coli (ETEC) K88, inhibitory activities of more than 1100 LAB strains isolated from different materials, and kept in the lab, were evaluated in this study. Nine strains with inhibition zones, at least 22...