Skeletal muscle response to short endurance training in heart transplant recipients

• Published in: Journal of the American College of Cardiology Vol. 32; no. 2; pp. 420 - 426
• Main Authors: Lampert, Eliane, Mettauer, Bertrand, Hoppeler, Hans, Charloux, Anne, Charpentier, Arnaud, Lonsdorfer, Jean
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.08.1998; Elsevier Science
• Subjects: Adult; Anaerobic Threshold - physiology; Anatomy, Cross-Sectional; Biological and medical sciences; Biopsy; Capillaries - ultrastructure; Case-Control Studies; Exercise Test; Exercise Therapy; Exercise Tolerance; Female; Heart Transplantation - physiology; Heart Transplantation - rehabilitation; Humans; Immunosuppressive Agents - therapeutic use; Male; Medical sciences; Middle Aged; Mitochondria, Muscle - ultrastructure; Muscle Fibers, Skeletal - ultrastructure; Muscle, Skeletal - anatomy & histology; Muscle, Skeletal - diagnostic imaging; Muscle, Skeletal - physiology; Muscle, Skeletal - ultrastructure; Oxygen Consumption - physiology; Physical Endurance - physiology; Respiration - physiology; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Tomography, X-Ray Computed; Work Capacity Evaluation; CT; TGF-β; C; VEGF; V̇O2; HTRs; Heart; Human; Physical training; Cardiovascular disease; Exploration; Transplantation; Electron microscopy; Homotransplantation; Striated muscle; Coronary heart disease; Treatment; Biopsy; Ultrastructure; Surgery; Endurance; Rehabilitation; Morphometry

Objectives. We sought to examine the effects of endurance training on the ultrastructural characteristics of skeletal muscle in heart transplant recipients (HTRs) and age-matched control subjects (C). Background. Deconditioning is one of the factors involved in the peripheral limitation of exercise...