Neutrophil Chemotaxis on Silicone and Polyurethane Surfaces

• Published in: The Journal of infectious diseases Vol. 180; no. 5; pp. 1603 - 1607
• Main Authors: Indorf, Amy S., Poate, Tim, Sherertz, Robert J.
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 01.11.1999; University of Chicago Press; Oxford University Press
• Subjects: Biological and medical sciences; Blood; Catheterization - instrumentation; Catheters; Chemotaxis; Chemotaxis, Leukocyte; Complement activation; Glass; Humans; Infections; Leukocytes; Major Articles; Medical sciences; N-Formylmethionine Leucyl-Phenylalanine - pharmacology; Neutrophils; Neutrophils - physiology; Phagocytosis; Polymers; Polyurethanes; Silicones; Surface Properties; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Technology. Biomaterials. Equipments; Zymosan - pharmacology; Infection; Sample preparation; Risk factor; Catheter; Biocompatibility; Neutrophil; Chemotaxis; In vitro; Silicone elastomer; Polyurethane elastomer

Silicone vascular catheters have a greater risk of infection and produce greater inflammation in vivo and greater complement activation in vitro than other vascular catheter polymer materials. This study investigated whether polymorphonuclear leukocyte (PMNL) chemotaxis under agarose on silicone sur...