Post‐prandial reflux suppression by a raft‐forming alginate (Gaviscon Advance) compared to a simple antacid documented by magnetic resonance imaging and pH‐impedance monitoring: mechanistic assessment in healthy volunteers and randomised, controlled, double‐blind study in reflux patients - Sweis, R.; Kaufman, E.; Anggiansah, A.; Wong, T.; Dettmar, P.; Fried, M.; Schwizer, W.; Avvari, R. K.; Pal, A.; Fox, M. (Alimentary pharmacology & therapeutics, 2013)
Keywords: Adult; Aged; Alginates - therapeutic use; Aluminum Hydroxide - therapeutic use; Antacids - therapeutic use; Biological and medical sciences; Cross-Over Studies; Digestive system; Double-Blind Method; Drug Combinations; Electric Impedance; Esophageal pH Monitoring; Female; Gastroenterology. Liver. Pancreas. Abdomen; Gastroesophageal Reflux - diagnosis; Gastroesophageal Reflux - drug therapy; Humans; Hydrogen-Ion Concentration; Magnesium Oxide - therapeutic use; Magnetic Resonance Imaging; Male; Manometry; Medical sciences; Middle Aged; Pharmacology. Drug treatments; Postprandial Period; Silicic Acid - therapeutic use; Sodium Bicarbonate - therapeutic use; Treatment Outcome; Human; Evaluation; Healthy subject; Alginates; Document; Nuclear magnetic resonance imaging; Randomization; Surveillance; Double blind study; pH; Medical imagery; Impedance; Antiacid; Comparative study